Acroosteolysis Dominant Type, also known as AOD, is a rare genetic condition. This condition results from a mutation or error in a person’s DNA or genes. This can cause birth defects such as skull deformities, cleft lip, low set ears, bushy eyebrows, and down slanted eyes. Acroosteolysis dominant type is usually diagnosed late in childhood when the fingertips and toes appear to absorb back into the hand or foot. Osteoporosis of the bones is also a common symptom that occurs near the end of childhood. This means the bones become more fragile and are more easily breakable than normal. Osteoporosis can be diagnosed using a test called a bone density X-ray, which uses x-rays to look at the bone strength. In addition, patients with acroosteolysis dominant type might also experience hearing loss, an abnormally deep voice, teeth loss, and infections in the nose, throat, or lungs that reoccurs often. Although there is currently no cure for acroosteolysis dominant type, patients have a normal life expectancy, and there are a few options for osteoporosis treatment. These treatments include drugs that act to strengthen the bones and prevent the loss of bone mass.