Acute monoblastic leukemia is also known as acute monocytic leukemia. It is a type of cancer affecting the blood. Although the precise cause of this disorder is not fully understood, exposure to radiation and certain medications are considered risk factors for this condition. In addition, this condition has also been shown to be associated with exposure to marijuana and parental exposure to certain pesticides and cleaning agents. Acute monoblastic leukemia may cause various symptoms such as fatigue, breathing problems and fever. A physician can often diagnose this condition with a physical exam and blood tests, although certain imaging studies such as an x-ray or CT scan might be necessary. Treatment for cancers of the blood, including acute monoblastic leukemia, is rapidly progressing with advances in medical research. Currently, treatment will often involve intensive chemotherapy and bone marrow transplant.