Alcohol dependence

Common Name(s)

Alcohol dependence, Alcoholism, Alcohol addiction

Alcoholism means a person is physically or mentally dependent on alcohol. It is a serious medical condition. People with alcoholism often struggle to live normal lives. They may try to hide their problem. Yet drinking too much alcohol can lead to poor life choices such as drinking and driving. Alcohol can cause serious health consequences. Symptoms of alcoholism may include not being able to stop drinking or having a hard time controlling how much you drink, needing more alcohol to feel good, spending a lot of time drinking and recovering from drinking, giving up other activities so you can drink, and withdrawal symptoms if you stop drinking or wait too long between drinks. Withdrawal symptoms may include feeling sick to your stomach, sweating, shakiness and anxiety. Alcoholism may interfere with your relationships and your ability to perform your job.

Alcoholism may be caused by a variety of factors. Genetic, psychological, social and environmental factors may all be part of the cause. Risk factors include steady drinking over time or binge drinking on a regular basis, starting to drink alcohol at a young age, a family history of alcoholism, and suffering from depression, bipolar disorder or anxiety. Alcoholism increases your risk for developing liver damage (cirrhosis), digestive problems, heart problems, sexual dysfunction, birth defects, bone loss, neurological complications and complications with diabetes. Alcoholism can weaken your immune system and increase your risk of certain cancers. Talk to your doctor if you or a family member may have an alcohol addiction. They may ask you a series of questions to determine if you are addicted to alcohol and to rule out other conditions. There are a variety of treatments to help you stop drinking including both inpatient and outpatient programs and private and group counseling. Your doctor can help you decide the best treatment plan for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alcohol dependence" for support, advocacy or research.

Logo
National Council on Alcoholism and Drug Dependence, Inc. (NCADD)

The National Council on Alcoholism and Drug Dependence, Inc. (NCADD) and its Affiliate Network is a voluntary health organization dedicated to fighting the Nation's #1 health problem -- alcoholism, drug addiction and the devastating consequences of alcohol and other drugs on individuals, families and communities.

Last Updated: 8 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alcohol dependence" for support, advocacy or research.

Logo
National Council on Alcoholism and Drug Dependence, Inc. (NCADD)

The National Council on Alcoholism and Drug Dependence, Inc. (NCADD) and its Affiliate Network is a voluntary health organization dedicated to fighting the Nation's #1 health problem -- alcoholism, drug addiction and the devastating consequences of alcohol and other drugs on individuals, families and communities.

https://ncadd.org/

Last Updated: 8 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Alcohol dependence" returned 824 free, full-text research articles on human participants. First 3 results:

Alcohol use, abuse and dependence in an older European population: Results from the MentDis_ICF65+ study.
 

Author(s): Manuel Muñoz, Berta Ausín, Ana B Santos-Olmo, Martin Härter, Jana Volkert, Holger Schulz, Susanne Sehner, Maria Christina Dehoust, Anna Suling, Karl Wegscheider, Alessandra Canuto, Mike J Crawford, Luigi Grassi, Chiara Da Ronch, Yael Hershkovitz, Alan Quirk, Ora Rotenstein, Arieh Y Shalev, Jens Strehle, Kerstin Weber, Hans-Ulrich Wittchen, Sylke Andreas

Journal:

 

Alcohol use disorders (AUD) in older people have been the subject of increasing interest in Europe and worldwide. However, thus far, no reliable data exist regarding the prevalence of AUD in people over the age of 65 years in Europe.

Last Updated: 31 Dec 1969

Go To URL
No association of CYP2E1 genetic polymorphisms with alcohol dependence in Han Taiwanese population.
 

Author(s): Cho-Yin Huang, Chung-Feng Kao, Chiao-Chicy Chen, Po-Hsiu Kuo, Ming-Chyi Huang

Journal: J. Formos. Med. Assoc.. 2018 Jul;117(7):646-649.

 

Cytochrome P450 2E1 (CYP2E1) gene is one of the candidate genes for alcohol dependence (AD). Four single nucleotide polymorphisms (SNPs) of CYP2E1 gene (CYP2E1*1D, *5B, *6 and *1B) have been associated with AD previously in other ethnic populations. To date, only CYP2E1*5B and *6 ...

Last Updated: 31 Dec 1969

Go To URL
The prevalence of alcohol dependence and its association with hypertension: a population-based cross-sectional study4 in Xuzhou city, China.
 

Author(s): Ailing Ji, Peian Lou, Zongmei Dong, Chunrong Xu, Pan Zhang, Guiqiu Chang, Ting Li

Journal:

 

To describe the prevalence of alcohol dependence and to explore the relationship between alcohol dependence and newly detected hypertension in China.

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Alcohol dependence" returned 105 free, full-text review articles on human participants. First 3 results:

Neurobiological Effects of Binge Drinking Help in Its Detection and Differential Diagnosis from Alcohol Dependence.
 

Author(s): Napoleon Waszkiewicz, Beata Galińska-Skok, Anastasiya Nestsiarovich, Agnieszka Kułak-Bejda, Karolina Wilczyńska, Katarzyna Simonienko, Mikołaj Kwiatkowski, Beata Konarzewska

Journal:

 

The prevalence of binge drinking in the general population is 3-4 times higher than that of alcohol dependence. Neuroimaging studies show that binge drinking in adolescence impairs brain development and white matter integrity. Regions with reduced functional activity include the limbic ...

Last Updated: 31 Dec 1969

Go To URL
Lack of associations of the opioid receptor mu 1 (OPRM1) A118G polymorphism (rs1799971) with alcohol dependence: review and meta-analysis of retrospective controlled studies.
 

Author(s): Xiangyi Kong, Hao Deng, Shun Gong, Theodore Alston, Yanguo Kong, Jingping Wang

Journal:

 

Studies have sought associations of the opioid receptor mu 1 (OPRM1) A118G polymorphism (rs1799971) with alcohol-dependence, but findings are inconsistent. We summarize the information as to associations of rs1799971 (A > G) and the alcohol-dependence.

Last Updated: 31 Dec 1969

Go To URL
Therapeutic interventions for alcohol dependence in non-inpatient settings: a systematic review and network meta-analysis (protocol).
 

Author(s): Hung-Yuan Cheng, Roy G Elbers, Julian P T Higgins, Abigail Taylor, Georgina J MacArthur, Luke McGuinness, Sarah Dawson, José A López-López, Sean Cowlishaw, Matthew Hickman, David Kessler

Journal:

 

Alcohol dependence is common and serious cause of social and physical harm. However, the optimal management of those with moderate and severe alcohol dependence in primary and community care after detoxification remains unclear. The aim of this review is to evaluate the effectiveness ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Defining the Clinical Role of Topiramate in the Treatment of Alcohol Dependence in Australia
 

Status: Recruiting

Condition Summary: Alcohol Dependence

 

Last Updated: 4 May 2018

Go to URL
A Tailored Physical Activity Smartphone App for Patients With Alcohol Dependence
 

Status: Recruiting

Condition Summary: Alcohol Dependence

 

Last Updated: 22 Jan 2018

Go to URL
Biomarkers to Measure Treatment Response for Alcohol Dependence
 

Status: Recruiting

Condition Summary: Alcohol Dependence

 

Last Updated: 15 Aug 2017

Go to URL