Churg-Strauss Syndrome

Common Name(s)

Churg-Strauss Syndrome, Allergic granulomatosis

Churg Strauss syndrome is a rare autoimmune condition characterized by asthma, high levels of eosinophils (a type of white blood cell that helps fight infection) in the blood and tissues, and inflammation of small to medium sized blood vessels (vasculitis). The inflamed vessels can affect various organ systems including the lungs, gastrointestinal tract, skin, heart and nervous system. The cause of Churg Strauss syndrome is unknown. While there is no cure, the condition can be successfully managed with early diagnosis and treatment.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Churg-Strauss Syndrome" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Churg-Strauss Syndrome" returned 229 free, full-text research articles on human participants. First 3 results:

Cutaneous manifestations of Churg-Strauss syndrome: key to diagnosis.
 

Author(s): Camila Carneiro Marques, Elizabeth Leocadia Fernandes, Gabriela Momente Miquelin, Mariana Morais Tavares Colferai

Journal: An Bras Dermatol. 2017 ;92(5 Suppl 1):56-58.

 

Churg-Strauss syndrome is a rare systemic vasculitis characterized by asthma and other allergy symptoms as well as eosinophilia and necrotizing vasculitis involving small and medium-sized vessels. Its prevalence in the general population ranges from 1-3 cases per million a year, varying ...

Last Updated: 31 Dec 1969

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Eosinophilic myocarditis as a first presentation of eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome).
 

Author(s): Ronan Bluett, David McDonnell, Claire O'Dowling, Carl Vaughan

Journal:

 

We present the case of a 28-year-old man who presented with chest pain and elevated cardiac biomarkers, with no evidence of acute ischaemia. He had a pronounced eosinophilia, abnormal echocardiographic, cardiac MRI and CT findings. He underwent transbronchial biopsy of carinal lymph ...

Last Updated: 31 Dec 1969

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Heart involvement in Churg-Strauss syndrome.
 

Author(s): Sigita Glaveckaite, Nomeda Valeviciene, Darius Palionis, Egle Kontrimaviciute, Eugenijus Lesinskas

Journal: Kardiol Pol. 2017 ;75(2):184.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Churg-Strauss Syndrome" returned 17 free, full-text review articles on human participants. First 3 results:

A case report and literature review of Churg-Strauss syndrome presenting with myocarditis.
 

Author(s): Lu Qiao, Dengfeng Gao

Journal: Medicine (Baltimore). 2016 Dec;95(51):e5080.

 

Churg-Strauss syndrome (CSS) is a multisystem disorder characterized by asthma, prominent peripheral blood eosinophilia, and vasculitis signs.

Last Updated: 31 Dec 1969

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Severe congestive heart failure as the main symptom of eosinophilic granulomatosis and polyangiitis (Churg-Strauss syndrome).
 

Author(s): Jolanta Załęska, Elżbieta Wiatr, Jacek Zych, Janusz Szopiński, Karina Oniszh, Jarosław Kober, Dorota Piotrowska-Kownacka, Kazimierz Roszkowski-Śliż

Journal: Pneumonol Alergol Pol. 2014 ;82(6):582-9.

 

Patients with cardiovascular symptoms are mainly diagnosed in cardiological wards. However, sometimes the other reasons for acute coronary syndrome and heart failure are found. One of such reasons is hypereosinophilia which can be recognized if number of blood eosinophils exceeds ...

Last Updated: 31 Dec 1969

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Multiple cerebral and cerebellar infarcts as the first clinical manifestation in a patient with Churg-Strauss syndrome: case report and literature review.
 

Author(s): Meng-Ju Cheng, Pai-Hao Huang, Pin-Wen Liao, Jen-Tse Chen, Tsuey-Ru Chiang

Journal: Acta Neurol Taiwan. 2012 Dec;21(4):169-75.

 

Churg-Strauss syndrome (CSS) is a rare autoimmune disease with small-vessel vasculitis. Neurological manifestation of CSS is common. Central nervous system is less frequently involved than that of peripheral nervous system.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Eosinophilic Granulomatosis With Polyangiitis Cohort
 

Status: Recruiting

Condition Summary: Churg-Strauss Syndrome

 

Last Updated: 19 Sep 2017

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Determining Disease Activity Biomarkers in Individuals With Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss)
 

Status: Recruiting

Condition Summary: Eosinophilic Granulomatosis With Polyangiitis; Churg-Strauss Syndrome

 

Last Updated: 23 Apr 2018

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NUCALA® Special Drug Use Investigation (EGPA, Long-term)
 

Status: Not yet recruiting

Condition Summary: Churg-Strauss Syndrome

 

Last Updated: 2 Jul 2018

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