Alopecia Immunodeficiency

Common Name(s)

Alopecia Immunodeficiency

Alopecia Immunodeficiency refers to a disorder of the immune system that is characterized by a complete lack of hair at birth in addition to decreased hair growth throughout one's lifetime, and problems with the body's natural defense mechanisms (immune system). Hence, individuals with this disorder may be more susceptible to infection and disease. The condition is often diagnosed during childhood. Doctors diagnose this form of immune system disorder if a complete lack of hair at birth is observed. In addition, abnormalities in the full blood count (which looks at different types of blood cells) and antibody count (which helps quantify the power of the immune system) can help doctors diagnose this disorder. Treatment is developed on a case-by-case basis and depends on the nature of the immune system abnormality. Doctors may suggest injecting antibodies, which help fight infections, and other immune system components into the individual's body to strengthen the individual's immune system. They may also consider injecting bone marrow stem cells, which can later develop into immune system components. Doctors seek help from various therapists and community services to provide support and care for families affected by these disorders.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alopecia Immunodeficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alopecia Immunodeficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Alopecia Immunodeficiency" returned 2 free, full-text research articles on human participants. First 3 results:

Ancestral founder mutation of the nude (FOXN1) gene in congenital severe combined immunodeficiency associated with alopecia in southern Italy population.
 

Author(s): M Adriani, A Martinez-Mir, F Fusco, R Busiello, J Frank, S Telese, E Matrecano, M V Ursini, A M Christiano, C Pignata

Journal: Ann. Hum. Genet.. 2004 May;68(Pt 3):265-8.

 

Genetic alterations of the FOXN1 transcription factor, selectively expressed in thymic epithelia and skin, are responsible in both mice and humans for the Nude/SCID phenotype. The first described human FOXN1 mutation was a C792T transition in exon 5 resulting in the nonsense mutation ...

Last Updated: 31 Dec 1969

Go To URL
Alopecia totalis and vitiligo in common variable immunodeficiency.
 

Author(s): G Spickett, A G Prentice, T Wallington, A D Webster, H Chapel

Journal: Postgrad Med J. 1991 Mar;67(785):291-4.

 

Three cases of severe and irreversible alopecia occurring in patients with common variable immunodeficiency are described. In all three cases, hair loss developed after the diagnosis of immune deficiency; one of the patients also had extensive vitiligo. A fourth patient had vitiligo ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Alopecia Immunodeficiency" returned 0 free, full-text review articles on human participants.

 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.