Amyoplasia

Common Name(s)

Amyoplasia

Amyoplasia is a condition characterized by a generalized lack of newborn muscular development and growth. It is the most common form of arthrogryposis, a condition that results in stiff joints and the fixed flexion (bent position) of the joints due to abnormal muscle development or shortened muscles. In amyoplasia, the normal skeletal muscle is replaced by dense fibrous tissue and fat. Individuals with amyoplasia typically have involvement of the major joints including, elbows, knees, shoulder, hips, wrists and feet. There is no one single factor or specific genetic factora that causes amyoplasia, but the condition is thought to occur when there is a lack of movement of the baby in the mother’s womb. Mothers of affected children may report that their baby was unusually still during pregnancy. This may be due to the mother having a small womb or having a lack of fluids inside the womb for the baby to move freely. Because amyoplasia is considered a sporadic (happens by chance) condition, there is a very low recurrence risk for siblings of an affected child. Corrective surgery may be performed early, at around one year of age, to fix this condition. People with amyoplasia have a good long-term outlook as their difficulties can be overcome through physical therapy, occupational therapy, or surgery. Some may continue to need special braces or support to walk. If your child has been diagnoses with amyoplasia, talk with you pediatrician about the most current treatment options. Support groups are also a good source of information and can help you connect with other families dealing with amyoplasia.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Amyoplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Amyoplasia" returned 3 free, full-text research articles on human participants. First 3 results:

[Amyoplasia congenita].
 

Author(s): L Borja Andueza, M A Apilanez Urquiola, M A Cortajarena Altuna, I Martí Carrera

Journal: An Pediatr (Barc). 2014 Jul;81(1):63-5.

 

Last Updated: 31 Dec 1969

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Amyoplasia congenita of the lower extremity: report in a premature baby.
 

Author(s): Hyeon Soo Lee

Journal: Yonsei Med. J.. 2005 Aug;46(4):567-70.

 

Amyoplasia congenita is a diagnostic subgroup of children with arthrogryposis multiplex congenita (AMC). AMC is a relatively rare syndrome characterized by multiple joint contractures at birth. Amyoplasia congenita is the most common type of this syndrome with an occurrence rate of ...

Last Updated: 31 Dec 1969

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Amyoplasia congenita associated with hyperostosis frontalis interna.
 

Author(s): R N HERSON

Journal: Br Med J. 1947 Sep;2(4525):491.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Amyoplasia" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.