Anal cancer

Common Name(s)

Anal cancer

Anal Cancer is a type of cancer that affects the anal canal. Cancer is uncontrolled cell growth due to genetic changes. Cancer cells can invade surrounding tissues. The anus is a passage that connects the rectum, the end of the large intestines, to the outside part of the body. Symptoms include anal/rectal bleeding, lumps around the anal opening, recurring anal pain, anal itching, change in bowel habits, narrowing of the stools, anal discharge, and swollen lymph nodes (glands) in the anal or groin areas. Twenty percent (20%) of anal cancer cases show no symptoms. Although anal cancer most commonly affects individuals over the age 55, it is possible for anal cancer to occur at younger ages. People who are diagnosed with HPV (see also human papilloma virus) have an increased risk of developing this cancer. Other risk factors include unprotected sex, anal sex, smoking, weakened immune systems, open anal wounds, and pelvic radiation. Treatment of anal cancers includes surgery, radiation therapy, and chemotherapy, all which are very effective in curing the cancer. Diagnosis is usually done through an anal canal examination, stool tests, or colonoscopies, and can usually be found during a yearly physical check-up. If you or a family member has been diagnosed with anal cancer, talk with your doctor to learn about the most up to date treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anal cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

View Details
Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

View Details
Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

Last Updated: 6 Nov 2012

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anal cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

View Details
Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

View Details
Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

http://stupidcancer.org

Last Updated: 6 Nov 2012

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anal cancer" returned 176 free, full-text research articles on human participants. First 3 results:

Treatment outcomes and HPV characteristics for an institutional cohort of patients with anal cancer receiving concurrent chemotherapy and intensity-modulated radiation therapy.
 

Author(s): Corey C Foster, Andrew Y Lee, Larissa V Furtado, John Hart, Lindsay Alpert, Shu-Yuan Xiao, Neil H Hyman, Manish R Sharma, Stanley Liauw

Journal:

 

Intensity-modulated radiation therapy (IMRT) has been used to limit treatment-related toxicity for patients with anal squamous cell carcinoma (SCC). The treatment outcomes and HPV characteristics for a cohort of patients receiving definitive concurrent chemotherapy and IMRT are reported.

Last Updated: 31 Dec 1969

Go To URL
Incorporating FDG-PET-defined pelvic active bone marrow in the automatic treatment planning process of anal cancer patients undergoing chemo-radiation.
 

Author(s): Pierfrancesco Franco, Christian Fiandra, Francesca Arcadipane, Elisabetta Trino, Francesca Romana Giglioli, Riccardo Ragona, Umberto Ricardi

Journal:

 

To investigate whether the incorporation of FDG-PET into the automatic treatment planning process may be able to decrease the dose to active bone marrow (BM) for locally advanced anal cancer patients undergoing concurrent chemo-radiation (CHT-RT).

Last Updated: 31 Dec 1969

Go To URL
Social determinants of stage IV anal cancer and the impact of pelvic radiotherapy in the metastatic setting.
 

Author(s): Michael C Repka, Nima Aghdam, Andrew W Karlin, Keith R Unger

Journal: Cancer Med. 2017 Nov;6(11):2497-2506.

 

Anal cancer is a relatively rare malignancy, and a minority of patients present with metastatic disease in the United States. The National Cancer Database (NCDB) was used to identify factors associated with metastatic disease at presentation and evaluate the role of pelvic radiotherapy ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anal cancer" returned 43 free, full-text review articles on human participants. First 3 results:

Core outcome research measures in anal cancer (CORMAC): protocol for systematic review, qualitative interviews and Delphi survey to develop a core outcome set in anal cancer.
 

Author(s): Rebecca Fish, Caroline Sanders, Paula R Williamson, Andrew G Renehan

Journal:

 

The incidence of anal squamous cell carcinoma (ASCC) has increased threefold in the last 30 years. Initial treatment is chemoradiotherapy, associated with short-term and long-term side effects. Future therapy innovations aim to reduce morbidity in treatment of early tumours while ...

Last Updated: 31 Dec 1969

Go To URL
Cancer of the Anal Canal: Diagnosis, Staging and Follow-Up with MRI.
 

Author(s): Carole Durot, Anthony Dohan, Mourad Boudiaf, Vincent Servois, Philippe Soyer, Christine Hoeffel

Journal: Korean J Radiol. ;18(6):946-956.

 

Although a rare disease, anal cancer is increasingly being diagnosed in patients with risk factors, mainly anal infection with the human papilloma virus. Magnetic resonance imaging (MRI) with external phased-array coils is recommended as the imaging modality of choice to grade anal ...

Last Updated: 31 Dec 1969

Go To URL
Pelvic insufficiency fracture (PIF) incidence in patients treated with intensity-modulated radiation therapy (IMRT) for gynaecological or anal cancer: single-institution experience and review of the literature.
 

Author(s): Louis Bazire, Haoping Xu, Jean-Philippe Foy, Malika Amessis, Caroline Malhaire, Kim Cao, Anne De La Rochefordiere, Youlia M Kirova

Journal: Br J Radiol. 2017 May;90(1073):20160885.

 

To summarize the results of pelvic insufficiency fracture (PIF) incidence in patients with anal or gynaecological cancer treated by pelvic intensity-modulated radiation therapy (IMRT).

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Pembrolizumab in Refractory Metastatic Anal Cancer
 

Status: Recruiting

Condition Summary: Anal Cancer

 

Last Updated: 21 Jun 2018

Go to URL

Last Updated: 29 Mar 2018

Go to URL
Shared Decision Making With Anal Cancer Patients on Radiation Dose
 

Status: Recruiting

Condition Summary: Anal Cancer

 

Last Updated: 15 Nov 2017

Go to URL