Anaplastic Oligoastrocytoma

Common Name(s)

Anaplastic Oligoastrocytoma

Anaplastic oligoastrocytoma is a brain tumor that forms when two types of cells in the brain, called oligodendrocytes and astrocytes, rapidly increase in number to form a mass.  These brain cells are known as glial cells, which normally protect and support nerve cells in the brain.  Because an oligoastrocytoma is made up of a combination of two cell types, it is known as a mixed glioma.   An oligoastrocytoma is described as anaplastic when the tumor grows quickly and the cancer cells within the tumor have the potential to spread into surrounding brain tissue or to more distant parts of the body.  Oligoastrocytomas usually occur in a part of the brain called the cerebrum and are diagnosed in adults between the ages of 30 and 50.   The exact cause of this condition is unknown.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anaplastic Oligoastrocytoma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anaplastic Oligoastrocytoma" returned 3 free, full-text research articles on human participants. First 3 results:

Isolation and characterization of stem cell-like precursor cells from primary human anaplastic oligoastrocytoma.
 

Author(s): Liang Yi, Zhi-hua Zhou, Yi-fang Ping, Jian-hong Chen, Xiao-hong Yao, Hua Feng, Jia-you Lu, Ji Ming Wang, Xiu-wu Bian

Journal: Mod. Pathol.. 2007 Oct;20(10):1061-8.

 

A small population of stem cell-like precursors in solid tumors are linked to histological composition, progression, angiogenesis, metastasis, recurrence and drug resistance of a variety of malignant tumors. Oligoastrocytoma is the most common brain mixed glioma composed of mixed ...

Last Updated: 31 Dec 1969

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Neoadjuvant temozolomide followed by complete resection of a 1p- and 19q-deleted anaplastic oligoastrocytoma: case study.
 

Author(s): Alfredo D Voloschin, David N Louis, Garth R Cosgrove, Tracy T Batchelor

Journal: Neuro-oncology. 2005 Jan;7(1):97-100.

 

A 38-year-old woman presented with an infiltrative tumor of the right frontal lobe and genu of the corpus callosum that was deemed only partially resectable. A stereotactic biopsy was performed, which revealed a right frontal oligoastrocytoma that had some anaplastic features as well ...

Last Updated: 31 Dec 1969

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Efficacy and feasibility of standard procarbazine, lomustine, and vincristine chemotherapy in anaplastic oligodendroglioma and oligoastrocytoma recurrent after radiotherapy. A Phase II study.
 

Author(s): Alba Ariela Brandes, Alicia Tosoni, Francesca Vastola, Lara Maria Pasetto, Bartolomea Coria, Daniela Danieli, Paolo Iuzzolino, Marina Gardiman, Andrea Talacchi, Mario Ermani

Journal: Cancer. 2004 Nov;101(9):2079-85.

 

To the authors' knowledge, there is a scarcity of accurate data regarding the feasibility of standard chemotherapy with procarbazine, lomustine, and vincristine (PCV) in a homogeneous series of patients with primary anaplastic oligodendroglioma (AO) and oligoastrocytoma (AOA) that ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anaplastic Oligoastrocytoma" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma
 

Status: Recruiting

Condition Summary: Glioblastoma Multiforme; Anaplastic Oligoastrocytoma

 

Last Updated: 14 Mar 2018

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A Study on β-elemene as Maintain Treatment for Newly Diagnosed Malignant Gliomas
 

Status: Recruiting

Condition Summary: Anaplastic Oligoastrocytoma; Anaplastic Astrocytoma; Glioblastoma

 

Last Updated: 21 Feb 2018

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Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA
 

Status: Recruiting

Condition Summary: Glioblastoma; Anaplastic Astrocytoma; Anaplastic Oligoastrocytoma; Glioma; Brain Neoplasm; Brain Cancer; Brain Tumor; Brain Tumor, Recurrent; Brain Neoplasm, Malignant

 

Last Updated: 28 Feb 2018

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