Aniridia - Mental Retardation Syndrome refers to a form of intellectual disability that is characterized mainly by absent irises in the eyes, and below-average mental ability. Hence, individuals with this form of intellectual disability have severe vision problems. Loss of irises can cause other eye problems, including clouding of the lens (cataracts), involuntary eye movement (nystagmus), decreased vision in eyes that appear normal (lazy eye), and enlargement of the eyeball (buphthalmos). Like other individuals with intellectual disability, an individual with this condition often has problems with reasoning and solving problems, as well as performing day-to-day tasks. The condition is often diagnosed during childhood. Doctors diagnose this form of intellectual disability if loss of irises is observed. Signs like walking and talking late, slow mastering of basic tasks, and having difficulty remembering things may also suggest this condition in children. Treatment is developed on a case-by-case basis and depends on the specific needs of the patient. Eye specialists may suggest individuals undergo surgery to fix iris problems. Doctors seek help from various therapists and community services to provide support and care for families affected by intellectual disability.