Anthrax

Common Name(s)

Anthrax

Anthrax is a sickness caused by the bacterium Bacillus anthracis. Although anthrax is mostly seen in livestock and wild game, humans can be affected too through contact with sick animals. Anthrax can be passed through open skin wounds, consuming the bacteria, or inhaling it. Symptoms vary from skin sores and nausea to shock. Anthrax can be treated with antibiotics, however inhalation of the bacteria is more serious and sometimes fatal. If you or a family member has been diagnosed with anthrax, talk with your doctor about the most current treatment options available.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anthrax" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anthrax" returned 603 free, full-text research articles on human participants. First 3 results:

Anthrax protective antigen is a calcium-dependent serine protease.
 

Author(s): Lisanne Storm, Floris J Bikker, Kamran Nazmi, Albert G Hulst, Debora V der Riet-Van Oeveren, Enno C I Veerman, John P Hays, Wendy E Kaman

Journal: Virulence. 2018 ;9(1):1085-1091.

 

Bacillus anthracis secretes a three component exotoxin-complex, which contributes to anthrax pathogenesis. Formation of this complex starts with the binding of protective antigen (PA) to its cellular receptor. In this study, we report that PA is a calcium-dependent serine protease ...

Last Updated: 31 Dec 1969

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[Cutaneous anthrax, the last outbreak diagnosed in Chile].
 

Author(s): Sebastián Arellano, Daniela Soto, Ma Beatriz Reeves, Francisco Chávez, Rodrigo Loubies, Andrés Ojeda

Journal: Rev Chilena Infectol. 2018 04;35(2):195-197.

 

Anthrax is a zoonosis caused by a spore-forming bacterium, called Bacillus anthracis. Naturally it is of global distribution, with a predilection in agricultural zones with few norms of public veterinary health. Human contagion occurs through the consumption of diseased animal's meat ...

Last Updated: 31 Dec 1969

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A modified anthrax toxin-based enzyme-linked immunospot assay reveals robust T cell responses in symptomatic and asymptomatic Ebola virus exposed individuals.
 

Author(s): Bobby Brooke Herrera, Donald J Hamel, Philip Oshun, Rolake Akinsola, Alani S Akanmu, Charlotte A Chang, Philomena Eromon, Onikepe Folarin, Kayode T Adeyemi, Christian T Happi, Yichen Lu, Folasade Ogunsola, Phyllis J Kanki

Journal:

 

Ebola virus (EBOV) caused more than 11,000 deaths during the 2013-2016 epidemic in West Africa without approved vaccines or immunotherapeutics. Despite its high lethality in some individuals, EBOV infection can produce little to no symptoms in others. A better understanding of the ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anthrax" returned 71 free, full-text review articles on human participants. First 3 results:

Anthrax outbreaks in the humans - livestock and wildlife interface areas of Northern Tanzania: a retrospective record review 2006-2016.
 

Author(s): Elibariki Reuben Mwakapeje, Sol Høgset, Robert Fyumagwa, Hezron Emmanuel Nonga, Robinson Hammerthon Mdegela, Eystein Skjerve

Journal:

 

Anthrax outbreaks in Tanzania have been reported from the human, livestock and wildlife sectors over several years, and is among the notifiable diseases. Despite frequent anthrax outbreaks, there is no comprehensive dataset indicating the magnitude and distribution of the disease ...

Last Updated: 31 Dec 1969

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Alternative pre-approved and novel therapies for the treatment of anthrax.
 

Author(s): Breanne M Head, Ethan Rubinstein, Adrienne F A Meyers

Journal:

 

Bacillus anthracis, the causative agent of anthrax, is a spore forming and toxin producing rod-shaped bacterium that is classified as a category A bioterror agent. This pathogenic microbe can be transmitted to both animals and humans. Clinical presentation depends on the route of ...

Last Updated: 31 Dec 1969

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Tumor Targeting and Drug Delivery by Anthrax Toxin.
 

Author(s): Christopher Bachran, Stephen H Leppla

Journal:

 

Anthrax toxin is a potent tripartite protein toxin from Bacillus anthracis. It is one of the two virulence factors and causes the disease anthrax. The receptor-binding component of the toxin, protective antigen, needs to be cleaved by furin-like proteases to be activated and to deliver ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 2 Aug 2018

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BARDA Securing Anthrax Immunity For the Elderly
 

Status: Recruiting

Condition Summary: Anthrax

 

Last Updated: 7 Sep 2018

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A Field Study Evaluating Clinical Benefit and Safety of AIGIV (ANTHRASIL®) in Inhalational Anthrax Patients
 

Status: Not yet recruiting

Condition Summary: Inhalational Anthrax

 

Last Updated: 2 Aug 2018

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