Aortic aneurysm

Common Name(s)

Aortic aneurysm

An aortic aneurysm is a weakening and swelling in the wall of the aorta, the body's largest artery. If not treated, the aneurysm can burst and cause potentially lethal internal bleeding. The aorta is a highly elastic blood vessel, expanding and contracting based on blood flow needs. But if a portion of the aorta losses elasticity, an aneurysm can form, causing the weakened portion of the vessel to balloon outwards. People with conditions that put extra and prolonged stress on artery walls, such as those with high blood pressure or atherosclerosis (hardening of the artery walls), are at risk for an aortic aneurysm. Individuals who smoke, or who have family members who have had an aortic aneurysm, also have a heightened risk. Most aortic aneurysms do not have any symptoms, so physicians will usually conduct investigative screens for those at risk for the condition via ultrasound, MRI or CT-scan. Having an aneurysm increases the risk of blood clots and stroke (clots are more likely to form in the ballooned aortic wall). Treatment for an aortic aneurysm depends on the size and growth of the aneurysm and the health of the patient. For small, stable cases, the condition is usually managed with medication, healthy eating habits, and frequent observation. For large and/or growing cases, surgery may be required to repair the aneurysm site. A burst aortic aneurysm causes extreme pain and bleeding and causes death within minutes to hours if left untreated.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aortic aneurysm" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aortic aneurysm" returned 3125 free, full-text research articles on human participants. First 3 results:

Comparative effectiveness of open surgery versus endovascular repair for hemodynamically stable and unstable ruptured abdominal aortic aneurysm.
 

Author(s): Tiehao Wang, Jichun Zhao, Ding Yuan, Yukui Ma, Bin Huang, Yi Yang, Guojun Zeng

Journal: Medicine (Baltimore). 2018 Jul;97(27):e11313.

 

Several observational studies and randomized trials have compared open surgery (OS) and endovascular aortic repair (EVAR) for ruptured abdominal aortic aneurysm (rAAA). However, none of these studies addressed optimal management of hemodynamically (hd) unstable patients. Our objective ...

Last Updated: 31 Dec 1969

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Abdominal compartment syndrome and ruptured aortic aneurysm: Validation of a predictive test (SCA-AAR).
 

Author(s): Betty Leclerc, Lucie Salomon Du Mont, Anne-Laure Parmentier, Guillaume Besch, Simon Rinckenbach

Journal: Medicine (Baltimore). 2018 Jun;97(25):e11066.

 

The abdominal compartment syndrome (ACS) has been clearly identified as being one of the main causes of mortality after ruptured abdominal aortic aneurysm (rAAA). The ACS is defined as a sustained intra-abdominal pressure > 20 mm Hg associated with a new organ dysfunction or failure. ...

Last Updated: 31 Dec 1969

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An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm.
 

Author(s): Christian L Lino Cardenas, Chase W Kessinger, Yisha Cheng, Carolyn MacDonald, Thomas MacGillivray, Brian Ghoshhajra, Luai Huleihel, Saifar Nuri, Ashish S Yeri, Farouc A Jaffer, Naftali Kaminski, Patrick Ellinor, Neal L Weintraub, Rajeev Malhotra, Eric M Isselbacher, Mark E Lindsay

Journal:

 

Thoracic aortic aneurysm (TAA) has been associated with mutations affecting members of the TGF-β signaling pathway, or components and regulators of the vascular smooth muscle cell (VSMC) actomyosin cytoskeleton. Although both clinical groups present similar phenotypes, the existence ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aortic aneurysm" returned 238 free, full-text review articles on human participants. First 3 results:

Cardiovascular Disease in Ageing: An Overview on Thoracic Aortic Aneurysm as an Emerging Inflammatory Disease.
 

Author(s): Calogera Pisano, Carmela Rita Balistreri, Alessandro Ricasoli, Giovanni Ruvolo

Journal: Mediators Inflamm.. 2017 ;2017():1274034.

 

Medial degeneration associated with thoracic aortic aneurysm and acute aortic dissection was originally described by Erdheim as a noninflammatory lesion related to the loss of smooth muscle cells and elastic fibre fragmentation in the media. Recent evidences propose the strong role ...

Last Updated: 31 Dec 1969

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Spinal cord injury after thoracic endovascular aortic aneurysm repair.
 

Author(s): Hamdy Awad, Mohamed Ehab Ramadan, Hosam F El Sayed, Daniel A Tolpin, Esmerina Tili, Charles D Collard

Journal: Can J Anaesth. 2017 Dec;64(12):1218-1235.

 

Thoracic endovascular aortic aneurysm repair (TEVAR) has become a mainstay of therapy for aneurysms and other disorders of the thoracic aorta. The purpose of this narrative review article is to summarize the current literature on the risk factors for and pathophysiology of spinal ...

Last Updated: 31 Dec 1969

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Presence of periaortic gas in Clostridium septicum-infected aortic aneurysm aids in early diagnosis: a case report and systematic review of the literature.
 

Author(s): Fumihito Ito, Ryota Inokuchi, Akinori Matsumoto, Yoshibumi Kumada, Hideyuki Yokoyama, Tokiya Ishida, Katsuhiko Hashimoto, Masashi Narita, Kazuaki Shinohara

Journal:

 

Clostridium septicum-infected aortic aneurysm is a fatal and rare disease. We present a fatal case of C. septicum-infected aortic aneurysm and a pertinent literature review with treatment suggestions for reducing mortality rates.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluation of Branch Endografts in the Treatment of Aortic Aneurysms
 

Status: Recruiting

Condition Summary: Thoracoabdominal Aortic Aneurysm

 

Last Updated: 31 Oct 2017

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Last Updated: 25 Nov 2015

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Last Updated: 21 Mar 2018

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