Bifid Nose with or without Anorectal and Renal Anomalies or BNAR, is a very rare genetic disease. It affects fewer than one in one million individuals. The disease is characterized by a bifid nose. A bifid nose is a nose that is split into two half noses. Sometimes, the nose looks normal with just a bump down the center. In more serious cases, the nose will actually split into two distinct half noses. Individuals may also have an anus shifted towards the genitalia, narrowing of the anal opening, or no anal opening at all. Kidney problems can include abnormalities of one or both kidneys as well as missing kidneys. These conditions affect the way a body removes fecal matter and urine.
BNAR is an autosomal recessive genetic disease. This means the condition is inherited (passed through families) through genes. We inherit our genes in pairs, one from each parent typically. Our genes are what control the growth, development and function of our bodies. If a mistake or error occurs in a gene, it can cause problems. Autosomal recessive means that an individual must have two copies of the changed gene or mutation that causes the condition. A person with one changed gene would be a carrier of the condition but usually will not have any symptoms. If both parents are carriers, their children have a one in four chance (25%) of having the disease.
Surgery may be done to fix the nose and other abnormalities. If you have been diagnossed with BNAR, speak with your doctor about the best personal plan of action.
Description Last Updated: May 30, 2018