Dandruff

Common Name(s)

Dandruff

Dandruff is a condition that causes the skin on the top of the head (scalp) to shed dry flakes. Dandruff is typically not a serious condition, but it can be irritating. The main symptom of dandruff is white, oily flakes of dead skin in the hair and on the shoulder. The scalp may also itch. The condition tends to be worse during fall and winter when indoor heating tends to dry out the skin. Babies can get a special type of dandruff, called cradle cap, that can last until 3 years of age.

There are several causes of dandruff, including dry skin, oily skin, not shampooing enough, having a yeast-like fungus called malassezia on the scalp, or sensitivity to hair-care products. Risk factors include age (dandruff is common in young and middle aged people), gender (dandruff is more common in males), and having oily hair. Dandruff can usually be treated easily at home using a shampoo made to treat dandruff. Not all dandruff shampoos are the same, so it is best to test out different types and see which one works best. The different types of dandruff shampoos include zinc pyrithione, tar-based, salicylic acid, selenium sulfide, and ketoconazole shampoo. If you have dandruff, talk with your doctor to discuss which treatment option is best for you.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dandruff" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dandruff" returned 22 free, full-text research articles on human participants. First 3 results:

Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates.
 

Author(s): Alessio Nocentini, Daniela Vullo, Sonia Del Prete, Sameh M Osman, Fatmah A S Alasmary, Zeid AlOthman, Clemente Capasso, Fabrizio Carta, Paola Gratteri, Claudiu T Supuran

Journal: J Enzyme Inhib Med Chem. 2017 Dec;32(1):1064-1070.

 

A series of monothiocarbamates (MTCs) was investigated for the inhibition of the β-class carbonic anhydrase (CAs, EC 4.2.1.1) from the fungal parasite Malassezia globosa, MgCA. These MTCs incorporate various scaffolds, among which aliphatic amine with 1-4 carbons atom in their molecule, ...

Last Updated: 31 Dec 1969

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Evaluation of therapeutic potential of VB-001, a leave-on formulation, for the treatment of moderate adherent dandruff.
 

Author(s): Anamika Bhattacharyya, Nilu Jain, Sudhanand Prasad, Shilpi Jain, Vishal Yadav, Shamik Ghosh, Shiladitya Sengupta

Journal:

 

Dandruff is a common scalp condition characterized by excessive scaling and itch. Aberrant colonization of the scalp by commensal Malassezia spp. is a major contributor in the multifactorial etiology of dandruff. Literature based understanding of Malassezia linked pathophysiology ...

Last Updated: 31 Dec 1969

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[How I treat … dandruff using a shampoo with a sulfate-free tensio-active].
 

Author(s): P Reygagne, G E Piérard, G Loussouarn, N Le Nôtre, S Ziane

Journal: Rev Med Liege. 2016 Sep;71(9):365-370.

 

A new formulation of an anti-dandruff shampoo containing a surfactant devoid of a sulfate-type anionic part has been assessed in vivo in 41 subjects. Introducing a welltried agent, the 0.5 % piroctone olamine confers to this shampoo a high anti-dandruff efficacy, a reduction in the ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dandruff" returned 5 free, full-text review articles on human participants. First 3 results:

Last Updated: 31 Dec 1969

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[How I treat dandruff].
 

Author(s): C Piérard-Franchimont, G E Piérard

Journal: Rev Med Liege. 2013 Sep;68(9):436-9.

 

Dandruff and seborrheic dermatitis form a continuum of desquamative conditions associated with the excessive colonization of the stratum corneum by yeasts of the genus Malassezia spp. Such colonization is heterogeneous in density, ranging from discrete to abundant according to the ...

Last Updated: 31 Dec 1969

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Malassezia fungi are specialized to live on skin and associated with dandruff, eczema, and other skin diseases.
 

Author(s): Charles W Saunders, Annika Scheynius, Joseph Heitman

Journal: PLoS Pathog.. 2012 ;8(6):e1002701.

 

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.