Dengue

Common Name(s)

Dengue, Dengue virus, susceptibility to

Dengue is a virus that is carried by mosquitos and affects over 100 million people worldwide each year. The virus is passed to humans through mosquito bites. Those who inhabit or visit tropical or sub-tropical regions, particularly in urban or suburban areas, are most at risk for infection. Symptoms of Dengue include a high fever, intense headache or aching behind the eyes, joint pain, easy bruising, gum or nose bleeds, bone and muscle pain, swollen glands, and a rash. Symptoms usually appear 4-10 days after infection and last for 2-7 days.

There are four types of dengue virus: DEN-1, DEN-2, DEN-3, and DEN-4. Once an individual has recovered from one of these types, that individual will not develop symptoms from that same type again. When an individual is infected by a different type, however, there is a risk for severe dengue. Symptoms of severe dengue include vomiting (sometimes bloody), tiredness, severe stomach pain, fast breathing, restlessness, and bleeding gums. These symptoms occur after the high fever of dengue has dropped. Severe dengue requires immediate treatment, as it can cause the liquid part of the blood (plasma) to leak from small blood vessels (capillaries). This condition leads to severe loss of blood volume (shock) and can be life-threatening. Other complications may include internal bleeding, difficulty breathing, and accumulation of fluid in the body.

Severe dengue is treated by fluid replacement therapy. Dengue prevention methods focus on avoiding mosquitos, such as by getting rid of stagnant water in containers where mosquitos lay eggs and using bed nets during the night and mosquito repellant when outdoors. If you have been diagnosed with dengue, talk to your doctor about current treatment options. In addition, consult a medical professional for advice before traveling to areas where there is a potential to be infected by the dengue virus.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dengue" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dengue" returned 3981 free, full-text research articles on human participants. First 3 results:

Regulation of midgut cell proliferation impacts Aedes aegypti susceptibility to dengue virus.
 

Author(s): Mabel L Taracena, Vanessa Bottino-Rojas, Octavio A C Talyuli, Ana Beatriz Walter-Nuno, José Henrique M Oliveira, Yesseinia I Angleró-Rodriguez, Michael B Wells, George Dimopoulos, Pedro L Oliveira, Gabriela O Paiva-Silva

Journal:

 

Aedes aegypti is the vector of some of the most important vector-borne diseases like dengue, chikungunya, zika and yellow fever, affecting millions of people worldwide. The cellular processes that follow a blood meal in the mosquito midgut are directly associated with pathogen transmission. ...

Last Updated: 31 Dec 1969

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Evaluating the use of fluorescence-based flow cytometry assay for dengue diagnosis using peripheral blood mononuclear cells.
 

Author(s): Luzia Aparecida Costa Barreira, Priscila Santos Scheucher, Marilia Farignoli Romeiro, Leonardo La Serra, Soraya Jabur Badra, William Marciel de Souza, Luiz Tadeu Moraes Figueiredo

Journal: Rev. Soc. Bras. Med. Trop.. ;51(2):168-173.

 

Dengue virus (DENV) is the most important arthropod-borne viral disease worldwide with an estimated 50 million infections occurring each year.

Last Updated: 31 Dec 1969

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Contributions from the silent majority dominate dengue virus transmission.
 

Author(s): Quirine A Ten Bosch, Hannah E Clapham, Louis Lambrechts, Veasna Duong, Philippe Buchy, Benjamin M Althouse, Alun L Lloyd, Lance A Waller, Amy C Morrison, Uriel Kitron, Gonzalo M Vazquez-Prokopec, Thomas W Scott, T Alex Perkins

Journal:

 

Despite estimates that, each year, as many as 300 million dengue virus (DENV) infections result in either no perceptible symptoms (asymptomatic) or symptoms that are sufficiently mild to go undetected by surveillance systems (inapparent), it has been assumed that these infections ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dengue" returned 311 free, full-text review articles on human participants. First 3 results:

Dengue Virus and Its Inhibitors: A Brief Review.
 

Author(s): Yu-Shi Tian, Yi Zhou, Tatsuya Takagi, Masanori Kameoka, Norihito Kawashita

Journal: Chem. Pharm. Bull.. 2018 ;66(3):191-206.

 

The global occurrence of viral infectious diseases poses a significant threat to human health. Dengue virus (DENV) infection is one of the most noteworthy of these infections. According to a WHO survey, approximately 400 million people are infected annually; symptoms deteriorate in ...

Last Updated: 31 Dec 1969

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The association between obesity and dengue severity among pediatric patients: A systematic review and meta-analysis.
 

Author(s): Mohd Syis Zulkipli, Maznah Dahlui, Nor'ashikin Jamil, Devi Peramalah, Hoe Victor Chee Wai, Awang Bulgiba, Sanjay Rampal

Journal:

 

Severe dengue infection often has unpredictable clinical progressions and outcomes. Obesity may play a role in the deterioration of dengue infection due to stronger body immune responses. Several studies found that obese dengue patients have a more severe presentation with a poorer ...

Last Updated: 31 Dec 1969

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Transmission of dengue virus from deceased donors to solid organ transplant recipients: case report and literature review.
 

Author(s): Fernando Rosso, Juan C Pineda, Ana M Sanz, Jorge A Cedano, Luis A Caicedo

Journal: Braz J Infect Dis. ;22(1):63-69.

 

Dengue fever is a vector-transmitted viral infection. Non-vectorial forms of transmission can occur through organ transplantation. We reviewed medical records of donors and recipients with suspected dengue in the first post-transplant week. We used serologic and molecular analysis ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 19 Jan 2018

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The Use of Biomarkers in Predicting Dengue Outcome
 

Status: Recruiting

Condition Summary: Dengue

 

Last Updated: 24 Oct 2016

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