Dengue

Common Name(s)

Dengue, Dengue virus, susceptibility to

Dengue is a virus that is carried by mosquitos and affects over 100 million people worldwide each year. The virus is passed to humans through mosquito bites. Those who inhabit or visit tropical or sub-tropical regions, particularly in urban or suburban areas, are most at risk for infection. Symptoms of Dengue include a high fever, intense headache or aching behind the eyes, joint pain, easy bruising, gum or nose bleeds, bone and muscle pain, swollen glands, and a rash. Symptoms usually appear 4-10 days after infection and last for 2-7 days.

There are four types of dengue virus: DEN-1, DEN-2, DEN-3, and DEN-4. Once an individual has recovered from one of these types, that individual will not develop symptoms from that same type again. When an individual is infected by a different type, however, there is a risk for severe dengue. Symptoms of severe dengue include vomiting (sometimes bloody), tiredness, severe stomach pain, fast breathing, restlessness, and bleeding gums. These symptoms occur after the high fever of dengue has dropped. Severe dengue requires immediate treatment, as it can cause the liquid part of the blood (plasma) to leak from small blood vessels (capillaries). This condition leads to severe loss of blood volume (shock) and can be life-threatening. Other complications may include internal bleeding, difficulty breathing, and accumulation of fluid in the body.

Severe dengue is treated by fluid replacement therapy. Dengue prevention methods focus on avoiding mosquitos, such as by getting rid of stagnant water in containers where mosquitos lay eggs and using bed nets during the night and mosquito repellant when outdoors. If you have been diagnosed with dengue, talk to your doctor about current treatment options. In addition, consult a medical professional for advice before traveling to areas where there is a potential to be infected by the dengue virus.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dengue" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dengue" returned 3771 free, full-text research articles on human participants. First 3 results:

Symptoms associated with adverse dengue fever prognoses at the time of reporting in the 2015 dengue outbreak in Taiwan.
 

Author(s): Chun-Yin Yeh, Po-Lin Chen, Kun-Ta Chuang, Yu-Chen Shu, Yu-Wen Chien, Guey Chuen Perng, Wen-Chien Ko, Nai-Ying Ko

Journal:

 

Tainan experienced the most severe dengue epidemic in Taiwan in 2015. This study investigates the association between the signs and symptoms at the time of reporting with the adverse dengue prognoses.

Last Updated: 31 Dec 1969

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Analysing increasing trends of Guillain-Barré Syndrome (GBS) and dengue cases in Hong Kong using meteorological data.
 

Author(s): Xiujuan Tang, Shi Zhao, Alice P Y Chiu, Xin Wang, Lin Yang, Daihai He

Journal:

 

Guillain-Barré Syndrome (GBS) is a severe paralytic neuropathy associated with virus infections such as Zika virus and Chikungunya virus. There were also case reports of dengue fever preceding GBS. With the aim to understand the mechanisms of GBS and dengue outbreaks, this ecological ...

Last Updated: 31 Dec 1969

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RIG-I-like receptor activation by dengue virus drives follicular T helper cell formation and antibody production.
 

Author(s): Joris K Sprokholt, Tanja M Kaptein, John L van Hamme, Ronald J Overmars, Sonja I Gringhuis, Teunis B H Geijtenbeek

Journal:

 

Follicular T helper cells (TFH) are fundamental in orchestrating effective antibody-mediated responses critical for immunity against viral infections and effective vaccines. However, it is unclear how virus infection leads to TFH induction. We here show that dengue virus (DENV) infection ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dengue" returned 293 free, full-text review articles on human participants. First 3 results:

[Role of dendritic cells in infection by dengue virus: targets for replication and immune response].
 

Author(s): Jahnnyer Martínez, Juan C Hernández, Silvio Urcuqui-Inchima

Journal: Rev Chilena Infectol. 2017 Jun;34(3):249-256.

 

Dengue fever, caused by dengue virus (DENV) infection, is one of the most important diseases in the world, not only due to the high morbidity/mortality rates it causes, but also because of its great economic and social impact in tropical/subtropical countries. DENV infection has a ...

Last Updated: 31 Dec 1969

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Community effectiveness of indoor spraying as a dengue vector control method: A systematic review.
 

Author(s): Moody Samuel, Dorit Maoz, Pablo Manrique, Tara Ward, Silvia Runge-Ranzinger, Joao Toledo, Ross Boyce, Olaf Horstick

Journal:

 

The prevention and control of dengue rely mainly on vector control methods, including indoor residual spraying (IRS) and indoor space spraying (ISS). This study aimed to systematically review the available evidence on community effectiveness of indoor spraying.

Last Updated: 31 Dec 1969

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ANTI-VIRAL EFFECTS OF MEDICINAL PLANTS IN THE MANAGEMENT OF DENGUE: A SYSTEMATIC REVIEW.
 

Author(s): Éric Heleno Freira Ferreira Frederico, André Luiz Bandeira Dionísio Cardoso, Eloá Moreira-Marconi, Danúbia da Cunha de Sá-Caputo, Carlos Alberto Sampaio Guimarães, Carla da Fontoura Dionello, Danielle Soares Morel, Laisa Liane Paineiras-Domingos, Patricia Lopes de Souza, Samuel Brandão-Sobrinho-Neto, Rafaelle Pacheco Carvalho-Lima, Eliane de Oliveira Guedes-Aguiar, Rebeca Graça Costa-Cavalcanti, Cristiane Ribeiro Kutter, Mario Bernardo-Filho

Journal:

 

Dengue is considered as an important arboviral disease. Safe, low-cost, and effective drugs that possess inhibitory activity against dengue virus (DENV) are mostly needed to try to combat the dengue infection worldwide. Medicinal plants have been considered as an important alternative ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Use of Biomarkers in Predicting Dengue Outcome
 

Status: Recruiting

Condition Summary: Dengue

 

Last Updated: 24 Oct 2016

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