Dermatomyositis

Common Name(s)

Dermatomyositis

Dermatomyositis is one of a group of acquired muscle diseases called inflammatory myopathies (disorder of muscle tissue or muscles), which are characterized by chronic muscle inflammation accompanied by muscle weakness. The cardinal symptom is a skin rash that precedes or accompanies progressive muscle weakness.  Dermatomyositis may occur at any age, but is most common in adults in their late 40s to early 60s, or children between 5 and 15 years of age. There is no cure for dermatomyositis, but the symptoms can be treated. Options include medication, physical therapy, exercise, heat therapy (including microwave and ultrasound), orthotics and assistive devices, and rest. The cause of dermatomyositis is unknown.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dermatomyositis" for support, advocacy or research.

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Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

Last Updated: 15 Jul 2015

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

Last Updated: 14 Jan 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dermatomyositis" for support, advocacy or research.

Logo
Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 15 Jul 2015

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

http://www.myositis.org

Last Updated: 14 Jan 2013

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General Resources

Dermatomyositis

Learn more about Dermatomyositis, rare, autoimmune muscle and skin disease.

Updated 3 Mar 2018

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dermatomyositis" returned 771 free, full-text research articles on human participants. First 3 results:

STROBE: The correlation of Cyr61, CTGF, and VEGF with polymyositis/dermatomyositis.
 

Author(s): Ke-Xia Chai, Yu-Qi Chen, Pei-Lin Fan, Jie Yang, Xia Yuan

Journal: Medicine (Baltimore). 2018 Aug;97(34):e11775.

 

This study aims to explore the roles of cysteine-rich protein 61 (Cyr61/CCN1), connective tissue growth factor (CTGF/CCN2) and vascular endothelial growth factor (VEGF) in the vascular process of polymyositis (PM)/dermatomyositis (DM).Real-time quantitative polymerase chain reaction ...

Last Updated: 31 Dec 1969

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Thrombotic Microangiopathy with Polymyositis/Dermatomyositis: Three Case Reports and a Literature Review.
 

Author(s): Saeko Yamada, Hiroyuki Yamashita, Masahiro Nakano, Hiroaki Hatano, Toshiharu Sasaki, Yuko Takahashi, Hiroshi Kaneko

Journal: Intern. Med.. 2018 ;57(15):2259-2265.

 

Thrombotic microangiopathies (TMAs) rarely accompany polymyositis/dermatomyositis. We treated three patients with dermatomyositis combined with TMA. A literature review identified 13 previously reported cases. Exacerbation of myositis at the time of the TMA onset was observed in 62.5% ...

Last Updated: 31 Dec 1969

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Prevalence and reactivity of anti-melanoma differentiation-associated gene 5 (anti-MDA-5) autoantibody in Brazilian patients with dermatomyositis.
 

Author(s): Isabela Bruna Pires Borges, Marilda GuimarĂ£es Silva, Samuel Katsuyuki Shinjo

Journal: An Bras Dermatol. ;93(4):517-523.

 

There have been no studies to date on the frequency and reactivity of aanti-melanoma differentiation-associated gene 5 (anti-MDA-5) in samples from the Brazilian population with dermatomyositis.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dermatomyositis" returned 72 free, full-text review articles on human participants. First 3 results:

Dermatomyositis as an extrahepatic manifestation of hepatitis B virus-related hepatocellular carcinoma: A case report and literature review.
 

Author(s): Juqiang Han, Shuai Wang, Thomas Ngai Yeung Kwong, Jian Liu

Journal: Medicine (Baltimore). 2018 Aug;97(33):e11586.

 

Dermatomyositis is an idiopathic inflammatory myopathy with specific cutaneous manifestations, which is closely associated with malignancy. However, the exact mechanism remains elusive. Even less is known about dermatomyositis with hepatocellular carcinoma (HCC).

Last Updated: 31 Dec 1969

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Dermatomyositis: clinicopathological correlations.
 

Author(s): Paolo Sena, Andrea Gianatti, Daniele Gambini

Journal: G Ital Dermatol Venereol. 2018 Apr;153(2):256-264.

 

Dermatomyositis (DM) is a chronic autoimmune disease affecting primarily the skeletal muscle and the skin. Although the diagnosis is usually based upon clinical and laboratory findings, histopathology is helpful for confirmation purposes and is mandatory in amiopathic DM where there ...

Last Updated: 31 Dec 1969

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Pleurisy Caused by Mycobacterium abscessus in a Young Patient with Dermatomyositis: A Case Report and Brief Review of the Literature.
 

Author(s): Shingo Noguchi, Kentaro Hanami, Hiroko Miyata, Ryo Torii, Ikuko Shimabukuro, Satoshi Kubo, Hideto Obata, Chiharu Yoshii, Kazuhiro Yatera

Journal: Intern. Med.. 2018 Apr;57(7):997-1002.

 

M. abscessus is a rapidly growing mycobacteria (RGM) and is the most common cause of pulmonary RGM infection. M. abscessus pleurisy is extremely rare. We herein report the case of a young patient with M. abscessus pleurisy without any lung lesions. A laboratory analysis of the pleural ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Tofacitinib in Refractory Dermatomyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis

 

Last Updated: 15 Feb 2018

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Juvenile Dermatomyositis
 

Status: Recruiting

Condition Summary: Juvenile Dermatomyositis

 

Last Updated: 23 Feb 2018

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Abatacept in Juvenile Dermatomyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis

 

Last Updated: 5 Sep 2018

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