Drug allergy

Common Name(s)

Drug allergy, Drug allergies

A drug allergy is the abnormal reaction of the body’s immune system to a drug or medication. Your immune system helps protect you from viruses and bacteria. In this case, the immune system mistakes the drug for a harmful substance. It makes chemicals, like histamine, to attack and get rid of the medication. Mild to moderate symptoms of a drug allergy may include a skin rash, hives, itchy skin or eyes, congestion, and swelling in the mouth or throat. More severe symptoms may include difficulty breathing, blueness of the skin, dizziness, fainting, anxiety, confusion, rapid pulse, diarrhea, and abdominal or stomach problems such as vomiting or cramps. The more severe symptoms may indicate that a person is in danger of going into anaphylaxis which is a rare but life threatening reaction needing immediate emergency medical care.

Over-the-counter, prescription, and herbal medications are all capable of producing a drug allergy. Certain medications, like antibiotics, aspirin, Echinacea, or bee pollen products, are more likely to cause an allergic reaction. Other risk factors include a family history of drug allergies, a personal history of other allergies, prolonged or frequent use of a medication or high dose of a medication, as well as certain illnesses such as an infection with HIV or the Epstein Barr virus.

Diagnosis of a drug allergy may include a thorough physical exam, skin tests and blood tests. Treatment depends on the severity and type of the reaction, but usually focuses on symptom relief and prevention of a severe reaction. Severe symptoms (which may be signs of anaphylaxis) require emergency medical treatment and may include hospitalization. If you or a family member is experiencing signs of an allergic reaction to a medication, call your doctor's office. If you are having difficulty breathing or have any severe symptoms or a previous history of anaphylaxis, seek medical attention immediately.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Drug allergy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Drug allergy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Drug allergy" returned 49 free, full-text research articles on human participants. First 3 results:

Iodinated Contrast Media and the Alleged "Iodine Allergy": An Inexact Diagnosis Leading to Inferior Radiologic Management and Adverse Drug Reactions.
 

Author(s): Ingrid Böhm, Knud Nairz, John N Morelli, Patricia Silva Hasembank Keller, Johannes T Heverhagen

Journal: Rofo. 2017 Apr;189(4):326-332.

 

Purpose To test the hypothesis that the incomplete diagnosis "iodine allergy" is a possibly dangerous concept for patients under routine radiologic conditions. Materials and Methods 300 patients with a history of an "iodine allergy" were retrospectively screened and compared with ...

Last Updated: 31 Dec 1969

Go To URL
Frequency and Risk Factors of Penicillin and Amoxicillin Allergy in Suspected Patients with Drug Allergy.
 

Author(s): Mohammad Reza Fazlollahi, Katayoon Bidad, Raheleh Shokouhi, Raheleh Dashti, Mohammad Nabavi, Masoud Movahedi, Mohammad Hasan Bemanian, Ali Reza Shafiei, Najmoddin Kalantari, Effat Sadat Farboud, Zahra Pourpak, Mostafa Moin

Journal: Arch Iran Med. 2017 Jan;20(1):34-37.

 

Unconfirmed beta-lactam allergy is a significant public health problem because of the limitations it imposes in drug selection. In this study, we aimed to evaluate patients referred for beta-lactam allergy to determine the frequency of confirmed beta-lactam allergy and identify some risk factors.

Last Updated: 31 Dec 1969

Go To URL
Cross sectional questionnaire-based internet study: Self-perception and clinical course of drug allergy in Greece.
 

Author(s): Michael P Makris, Theodoros N Sergentanis, Xenophon Aggelides, Stamatios Tzanninis, Efthimia Polyzou, Dimitrios Rigopoulos, Theodora Psaltopoulou

Journal: Allergol Int. 2017 Jan;66(1):59-63.

 

Data on self perception of drug allergy in the general population are lacking. Epidemiological studies focus either on specific populations or document adverse drug reactions in general. Our objective was to document self-reported drug allergy in Greece, through a simple, informative ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Drug allergy" returned 18 free, full-text review articles on human participants. First 3 results:

Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy.
 

Author(s): Lisa M Wheatley, Marshall Plaut, Julie M Schwaninger, Aleena Banerji, Mariana Castells, Fred D Finkelman, Gerald J Gleich, Emma Guttman-Yassky, Simon A K Mallal, Dean J Naisbitt, David A Ostrov, Elizabeth J Phillips, Werner J Pichler, Thomas A E Platts-Mills, Jean-Claude Roujeau, Lawrence B Schwartz, Lauren A Trepanier

Journal: J. Allergy Clin. Immunol.. 2015 Aug;136(2):262-71.e2.

 

Allergic reactions to drugs are a serious public health concern. In 2013, the Division of Allergy, Immunology, and Transplantation of the National Institute of Allergy and Infectious Diseases sponsored a workshop on drug allergy. International experts in the field of drug allergy ...

Last Updated: 31 Dec 1969

Go To URL
Evolving models of the immunopathogenesis of T cell-mediated drug allergy: The role of host, pathogens, and drug response.
 

Author(s): Katie D White, Wen-Hung Chung, Shuen-Iu Hung, Simon Mallal, Elizabeth J Phillips

Journal: J. Allergy Clin. Immunol.. 2015 Aug;136(2):219-34; quiz 235.

 

Immune-mediated (IM) adverse drug reactions (ADRs) are an underrecognized source of preventable morbidity, mortality, and cost. Increasingly, genetic variation in the HLA loci is associated with risk of severe reactions, highlighting the importance of T-cell immune responses in the ...

Last Updated: 31 Dec 1969

Go To URL
Antiviral drug allergy.
 

Author(s): Brigitte Milpied-Homsi, Ellen M Moran, Elizabeth J Phillips

Journal: Immunol Allergy Clin North Am. 2014 Aug;34(3):645-62, ix.

 

Antiviral drugs used to treat HIV and hepatitis C are common causes of delayed drug hypersensitivities for which many of the more severe reactions have been recently shown to be immunogenetically mediated such as abacavir hypersensitivity where HLA-B(∗)57:01 is now used routinely ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Medical Device for Drug Allergy Diagnosis
 

Status: Recruiting

Condition Summary: Drug Hypersensitivity

 

Last Updated: 18 Jul 2016

Go to URL
Management of Drug Hypersensitivity in Children
 

Status: Recruiting

Condition Summary: Drug Hypersensitivity

 

Last Updated: 8 Jan 2014

Go to URL
Study of Omalizumab as Adjuvant Therapy in Chemotherapy Desensitization
 

Status: Recruiting

Condition Summary: Drug Allergy

 

Last Updated: 6 Feb 2017

Go to URL