Huntington disease-like 1 is a genetic condition caused by a change in the IT15 gene. Genes are what control the growth, development, and function of the body. A change (mutation) in the gene causes it to not work properly. Each person has two copies of every gene, one from the mother and one from the father. Huntington disease-like 1 is passed down from parent to child in an autosomal dominant manner, meaning only one mutation from one parent is inherited by a child in order to cause symptoms. A person with this condition has a 50/50 chance of passing the condition on to their children.
Huntington disease-like 1 is similar to Huntington disease. It is a condition that affects brain functions, which can create changes in behavior, personality, or memory. Huntington disease-like 1 can affect someone’s ability to move, especially affecting coordination and involuntary movements. These symptoms often happen during mid-adulthood and can worsen as someone gets older. Other symptoms include inability to walk, speak, or swallow. If you or a family member has been diagnosed with Huntington disease-like 1, talk with your doctor about the most current treatment options as well as signs that you may need immediate medical attention.