Ebstein's anomaly

Common Name(s)

Ebstein's anomaly

Ebstein’s anomaly is a rare heart defect present at birth (congenital). In people with Ebstein’s anomaly, the tricuspid valve, which separates the two right chambers in the heart, is malformed. Normally, the tricuspid valve lets blood flow from the right atrium (upper chamber) to the right ventricle (lower chamber). In Ebstein’s anomaly, the valve is lower than it should be and allows blood to leak back into the atrium. This forces the heart to work harder, and can lead to heart enlargement or failure. Ebstein’s anomaly may be associated with atrial septal defects, heart arrhythmias and Wolff-Parkinson-White syndrome.

Symptoms may include shortness of breath, fatigue, heart palpitations (arrhythmias), or bluish skin or lips (cyanosis). Some people with Ebstein’s abnormality do not develop any severe symptoms, and many will not develop symptoms until later in adulthood. The causes of the anomaly are not yet known, but is believed to be caused by both genetic and environmental factors. People with a family history of heart defects or have heart defects themselves may be more likely to have a baby with Ebstein’s anomaly. A mother’s exposure to medications containing large amounts of lithium or benzodiazepines may also increase the risk for her baby.

Chest X-rays, ultrasounds, MRIs, or EKGs may be performed to diagnose Ebstein’s anomaly. All of these tests will allow a cardiologist to get a clearer picture of the heart. Treatments vary depending on the severity of the anomaly and the symptoms. Treatments can include regular monitoring, medications, surgery, or, in very severe cases, a heart transplant. If you or a loved one has been diagnosed with Ebstein’s anomaly, talk to a cardiologist (a heart doctor) about the most current treatment options. Support organizations and genetic counselors are also good sources of information and can help connect you with others affected by congenital heart conditions.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ebstein's anomaly" for support, advocacy or research.

Saving Little Hearts

Saving Little Hearts is dedicated to helping children with congenital heart defects and their families by providing emotional assistance and educational information primarily through the distribution of Care Packages.

Last Updated: 15 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ebstein's anomaly" for support, advocacy or research.

Saving Little Hearts

Saving Little Hearts is dedicated to helping children with congenital heart defects and their families by providing emotional assistance and educational information primarily through the distribution of Care Packages.

http://www.savinglittlehearts.com

Last Updated: 15 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ebstein's anomaly" returned 133 free, full-text research articles on human participants. First 3 results:

The modified cone reconstruction in the treatment of Ebstein's anomaly: Case reports.
 

Author(s): Jun-Sheng Li, Gang Chen, Jie Ma, Zi-Xing Yan, Dong-Ming Cheng, Liang Chang, Hai-Chun Zhang, Jiang-Yan Liu

Journal: Medicine (Baltimore). 2017 Dec;96(52):e8727.

 

To investigate the early and mid-term clinical outcomes of the modified cone reconstruction in the treatment of Ebstein's anomaly (EA) which provide appropriate surgical treatment for clinical and reduce the incidence of re-operation and valve replacement.

Last Updated: 31 Dec 1969

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Left ventricular synchrony, torsion, and recoil mechanics in Ebstein's anomaly: insights from cardiovascular magnetic resonance.
 

Author(s): Michael Steinmetz, Simon Usenbenz, Johannes Tammo Kowallick, Olga Hösch, Wieland Staab, Torben Lange, Shelby Kutty, Joachim Lotz, Gerd Hasenfuß, Thomas Paul, Andreas Schuster

Journal:

 

Disease progression and heart failure development in Ebstein's Anomaly (EA) of the tricuspid valve is characterized by both right and left ventricular (LV) deterioration. The mechanisms underlying LV dysfunction and their role in heart failure development are incompletely understood. ...

Last Updated: 31 Dec 1969

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Cardiac Resynchronization Therapy in Patients with Ebstein's Anomaly.
 

Author(s): Genri Numata, Eisuke Amiya, Toshiya Kojima, Katsuhito Fujiu, Masaru Hatano, Masafumi Watanabe, Issei Komuro

Journal: Int Heart J. 2017 Oct;58(5):816-819.

 

Ebstein's anomaly is a rare congenital heart disease characterized by apical displacement of the septal and posterior tricuspid valve leaflets. It is often complicated with left ventricular (LV) dysfunction as well as right-sided abnormalities. On the other hand, in the presence of ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ebstein's anomaly" returned 2 free, full-text review articles on human participants. First 3 results:

Ebstein's Anomaly: Genetics, Clinical Manifestations, and Management.
 

Author(s): Shi-Min Yuan

Journal: Pediatr Neonatol. 2017 06;58(3):211-215.

 

Ebstein's anomaly is uncommon. Genetic bases of this congenital heart defect may be related to the mutations in myosin heavy chain 7 and NKX2.5, among others. Asymptomatic patients with Ebstein's anomaly can be conservatively treated and kept under close follow-up, whereas surgical ...

Last Updated: 31 Dec 1969

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Electrode catheters and the diagnosis of Ebstein's anomaly of the tricuspid valve.
 

Author(s): H Watson

Journal: Br Heart J. 1966 Mar;28(2):161-71.

 

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Autologous Bone Marrow Derived Mononuclear Cells for Treatment of Ebstein Anomaly
 

Status: Recruiting

Condition Summary: Ebstein Anomaly

 

Last Updated: 5 Oct 2016

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