Eclampsia

Common Name(s)

Eclampsia

Eclampsia is a very serious condition in pregnant women. Eclampsia follows a condition called preeclampsia, which is caused by high blood pressure and large amounts of protein in the urine. If not treated, preeclampsia may turn into eclampsia, in which symptoms include intense headaches, confusion, vision changes, seizures and unconsciousness that may lead to a coma. Eclampsia is dangerous for both the mother and the baby, but in the majority of cases, preeclampsia is diagnosed and treated by a physician before it develops into eclampsia. Primary treatment for eclampsia involves recognition of preeclampsia and anti-seizure medication to prevent the woman from moving into eclampsia. If this is not done, treatment of eclampsia includes immediately delivering the baby and medication to control high blood pressure and stop seizures. Eclampsia is dangerous, but recognizing symptoms of preeclampsia early is the best way to prevent it.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 23 Oct 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

View Details
Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 23 Oct 2014

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General Resources

The Preeclampsia Registry

The Preeclampsia Registry is a "Living Database" bringing together those affected, their family members, and researchers to advance knowledge and discover preventions and treatments for preeclampsia, HELLP syndrome, and related hypertensive disorders

Updated 23 Oct 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Eclampsia" returned 1035 free, full-text research articles on human participants. First 3 results:

Clinical accuracy of the Omron M3 Comfort and the Omron Evolv for self-blood pressure measurements in pregnancy and pre-eclampsia - validation according to the Universal Standard Protocol.
 

Author(s): Jirar Topouchian, Zoya Hakobyan, Jennifer Asmar, Svetlana Gurgenian, Parounak Zelveian, Roland Asmar

Journal:

 

Electronic devices for blood pressure (BP) measurements need to go through independent clinical validation as recommended by different authorities, both in general and in special populations such as pregnancy.

Last Updated: 31 Dec 1969

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Economic evaluation of sFlt-1/PlGF ratio test in pre-eclampsia prediction and diagnosis in two Brazilian hospitals.
 

Author(s): Sarah Franco Figueira, Cyrill Wolf, Marisa D'Innocenzo, João Paulo Venezian de Carvalho, Mariana Granado Barbosa, Eduardo Zlotnik, Eduardo Cordioli

Journal: Pregnancy Hypertens. 2018 Jul;13():30-36.

 

To assess the economic impact of introducing the soluble FMS-like tyrosine kinase (sFlt-1) to placental growth factor (PlGF) ratio test into clinical practice in two Brazilian hospitals.

Last Updated: 31 Dec 1969

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Maternal and perinatal adverse outcomes in women with pre-eclampsia cared for at facility-level in South Africa: a prospective cohort study.
 

Author(s): Hannah L Nathan, Paul T Seed, Natasha L Hezelgrave, Annemarie De Greeff, Elodie Lawley, Frances Conti-Ramsden, John Anthony, Wilhelm Steyn, David R Hall, Lucy C Chappell, Andrew H Shennan

Journal: J Glob Health. 2018 Dec;8(2):020401.

 

Hypertensive disorders of pregnancy contribute to 14% of all maternal deaths, the majority of which occur in low- and middle-income countries. The aim of the study was to describe the maternal and perinatal clinical outcomes of women with pre-eclampsia living in middle- and low-income countries.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Eclampsia" returned 128 free, full-text review articles on human participants. First 3 results:

How to identify pregnant women at risk of pre-eclampsia? - a review of the current literature.
 

Author(s): Katarzyna Kosińska-Kaczyńska, Mirosław Wielgoś

Journal: Ginekol. Pol.. 2018 ;89(6):335-338.

 

Pre-eclampsia remains a major cause of poor perinatal outcome worldwide. As administering acetylsalicylic acid in a high risk population reduces the risk of PE, it is essential to identify women at risk of PE. Several algorithms for PE risk assessment have been developed. They include ...

Last Updated: 31 Dec 1969

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Prediction of adverse maternal outcomes from pre-eclampsia and other hypertensive disorders of pregnancy: A systematic review.
 

Author(s): U Vivian Ukah, Dane A De Silva, Beth Payne, Laura A Magee, Jennifer A Hutcheon, Helen Brown, J Mark Ansermino, Tang Lee, Peter von Dadelszen

Journal: Pregnancy Hypertens. 2018 Jan;11():115-123.

 

The hypertensive disorders of pregnancy are a leading cause of maternal and perinatal mortality and morbidity. The ability to predict these complications using simple tests could aid in management and improve outcomes. We aimed to systematically review studies that reported on potential ...

Last Updated: 31 Dec 1969

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[Haemorrhagic stroke of the brainstem secondary to postpartum eclampsia: about a case and literature review].
 

Author(s): Khadija Ennaqui, Assia Makayssi, Houssine Boufettal, Naima Samouh

Journal:

 

Strokes are rare but severe accidents during pregnancy and post-partum period. They are responsible for high mortality and morbidity rates. Pre-eclampsia, eclampsia, and strokes are significantly related. Endothelial dysfunction, alteration of brain self-regulation and severe hypertension ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Use of Sildenafil Citrate in Management of Mild Pre-eclampsia
 

Status: Recruiting

Condition Summary: Pre-Eclampsia; Mild

 

Last Updated: 24 Aug 2017

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Saccadic Reaction Time and Preterm Pre-eclampsia
 

Status: Recruiting

Condition Summary: Pre-eclampsia

 

Last Updated: 3 Apr 2017

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Podocyturia as Predictive Factor for Pre-eclampsia
 

Status: Not yet recruiting

Condition Summary: Pre-Eclampsia

 

Last Updated: 17 Oct 2017

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