Ependymoma

Common Name(s)

Ependymoma

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ependymoma" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

Last Updated: 7 Jan 2013

View Details
National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

Last Updated: 21 Nov 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ependymoma" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

http://www.abc2.org

Last Updated: 7 Jan 2013

View Details
National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

http://braintumor.org/

Last Updated: 21 Nov 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ependymoma" returned 218 free, full-text research articles on human participants. First 3 results:

Outcome predictors in the management of intramedullary classic ependymoma: An integrative survival analysis.
 

Author(s): Yinqing Wang, Ranze Cai, Rui Wang, Chunhua Wang, Chunmei Chen

Journal: Medicine (Baltimore). 2018 Jun;97(23):e10870.

 

This is a retrospective study.The aim of this study was to illustrate the survival outcomes of patients with classic ependymoma (CE) and identify potential prognostic factors.CE is the most common category of spinal ependymomas, but few published studies have discussed predictors ...

Last Updated: 31 Dec 1969

Go To URL
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.
 

Author(s): Stephen C Mack, Kristian W Pajtler, Lukas Chavez, Konstantin Okonechnikov, Kelsey C Bertrand, Xiuxing Wang, Serap Erkek, Alexander Federation, Anne Song, Christine Lee, Xin Wang, Laura McDonald, James J Morrow, Alina Saiakhova, Patrick Sin-Chan, Qiulian Wu, Kulandaimanuvel Antony Michaelraj, Tyler E Miller, Christopher G Hubert, Marina Ryzhova, Livia Garzia, Laura Donovan, Stephen Dombrowski, Daniel C Factor, Betty Luu, Claudia L L Valentim, Ryan C Gimple, Andrew Morton, Leo Kim, Briana C Prager, John J Y Lee, Xiaochong Wu, Jennifer Zuccaro, Yuan Thompson, Borja L Holgado, Jüri Reimand, Susan Q Ke, Adam Tropper, Sisi Lai, Senthuran Vijayarajah, Sylvia Doan, Vaidehi Mahadev, Ana Fernandez Miñan, Susanne N Gröbner, Matthias Lienhard, Marc Zapatka, Zhiqin Huang, Kenneth D Aldape, Angel M Carcaboso, Peter J Houghton, Stephen T Keir, Till Milde, Hendrik Witt, Yan Li, Chao-Jun Li, Xiu-Wu Bian, David T W Jones, Ian Scott, Sheila K Singh, Annie Huang, Peter B Dirks, Eric Bouffet, James E Bradner, Vijay Ramaswamy, Nada Jabado, James T Rutka, Paul A Northcott, Mathieu Lupien, Peter Lichter, Andrey Korshunov, Peter C Scacheri, Stefan M Pfister, Marcel Kool, Michael D Taylor, Jeremy N Rich

Journal: Nature. 2018 01;553(7686):101-105.

 

Genomic sequencing has driven precision-based oncology therapy; however, the genetic drivers of many malignancies remain unknown or non-targetable, so alternative approaches to the identification of therapeutic leads are necessary. Ependymomas are chemotherapy-resistant brain tumours, ...

Last Updated: 31 Dec 1969

Go To URL
Characterization of 2 Novel Ependymoma Cell Lines With Chromosome 1q Gain Derived From Posterior Fossa Tumors of Childhood.
 

Author(s): Vladimir Amani, Andrew M Donson, Seth C Lummus, Eric W Prince, Andrea M Griesinger, Davis A Witt, Todd C Hankinson, Michael H Handler, Kathleen Dorris, Rajeev Vibhakar, Nicholas K Foreman, Lindsey M Hoffman

Journal: J. Neuropathol. Exp. Neurol.. 2017 Jul;76(7):595-604.

 

Ependymoma (EPN) is a common brain tumor of childhood that, despite standard surgery and radiation therapy, has a relapse rate of 50%. Clinical trials have been unsuccessful in improving outcome by addition of chemotherapy, and identification of novel therapeutics has been hampered ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ependymoma" returned 25 free, full-text review articles on human participants. First 3 results:

Systemic metastases from central nervous system ependymoma: case report and review of the literature.
 

Author(s): Claudia Marsecano, Federico Bruno, Giulia Michelini, Marco Perri, Giuseppe Calvisi, Ernesto Di Cesare, Alessandra Splendiani

Journal: Neuroradiol J. 2017 Jun;30(3):274-280.

 

Ependymal tumours in adults are rare, accounting for less than 4% of primary tumours of the central nervous system, and exceptionally metastasise outside the nervous system. In this study, we present a case of anaplastic ependymoma, which developed metastases outside the nervous system ...

Last Updated: 31 Dec 1969

Go To URL
Cerebellar ependymoma with overlapping features of clear-cell and tanycytic variants mimicking hemangioblastoma: a case report and literature review.
 

Author(s): Xiu-Peng Zhang, Yang Liu, Di Zhang, Qin Zheng, Chen Wang, Liang Wang, Qing-Chang Li, Xue-Shan Qiu, En-Hua Wang

Journal:

 

Imaging and histology of clear-cell ependymoma and cerebellum-based hemangioblastoma are similar; distinguishing between them is a diagnostic challenge.

Last Updated: 31 Dec 1969

Go To URL
The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants.
 

Author(s): Kristian W Pajtler, Stephen C Mack, Vijay Ramaswamy, Christian A Smith, Hendrik Witt, Amy Smith, Jordan R Hansford, Katja von Hoff, Karen D Wright, Eugene Hwang, Didier Frappaz, Yonehiro Kanemura, Maura Massimino, Cécile Faure-Conter, Piergiorgio Modena, Uri Tabori, Katherine E Warren, Eric C Holland, Koichi Ichimura, Felice Giangaspero, David Castel, Andreas von Deimling, Marcel Kool, Peter B Dirks, Richard G Grundy, Nicholas K Foreman, Amar Gajjar, Andrey Korshunov, Jonathan Finlay, Richard J Gilbertson, David W Ellison, Kenneth D Aldape, Thomas E Merchant, Eric Bouffet, Stefan M Pfister, Michael D Taylor

Journal: Acta Neuropathol.. 2017 Jan;133(1):5-12.

 

Multiple independent genomic profiling efforts have recently identified clinically and molecularly distinct subgroups of ependymoma arising from all three anatomic compartments of the central nervous system (supratentorial brain, posterior fossa, and spinal cord). These advances motivated ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Everolimus for Children With Recurrent or Progressive Ependymoma
 

Status: Recruiting

Condition Summary: Recurrent Childhood Ependymoma

 

Last Updated: 30 Apr 2018

Go to URL
A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma
 

Status: Recruiting

Condition Summary: Ependymoma

 

Last Updated: 12 Sep 2017

Go to URL

Last Updated: 19 Jun 2018

Go to URL