Essential hypertension

Common Name(s)

Essential hypertension

The Pickering school held that blood pressure has a continuous distribution, that multiple genes and multiple environmental factors determine the level of one's blood pressure just as the determination of stature and intelligence is multifactorial, and that 'essential hypertension' is merely the upper end of the distribution ({66:Pickering, 1978}). In this view the person with essential hypertension is one who happens to inherit an aggregate of genes determining hypertension (and also is exposed to exogenous factors that favor hypertension). The Platt school took the view that essential hypertension is a simple mendelian dominant trait ({69:Platt, 1963}). {57:McDonough et al. (1964)} defended the monogenic idea. See {58:McKusick (1960)} and {52:Kurtz and Spence (1993)} for reviews. {78:Swales (1985)} reviewed the Platt-Pickering controversy as an 'episode in recent medical history.' The Pickering point of view appears to be more consistent with the observations.
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Advocacy and Support Organizations Health Questions Recommended Apps Scientific Literature Symptoms, Diagnosis, and Treatment Clinical Trial Information
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential hypertension" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Recommended Apps

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Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

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Relief is when you and the right researcher find each other

Finding the right clinical trial for Essential hypertension can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Essential hypertension" returned 1015 free, full-text research articles on human participants. First 3 results:

Genetic predisposition for essential hypertension, based on studies of genetic polymorphisms in modern global human populations: The perspective of evolutionary biology.
 

Author(s): Manuel Bicho

Journal: Rev Port Cardiol. 2018 06;37(6):509-510.

 

Last Updated: 31 Dec 1969

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Sonographic evaluation of renal parameters in individuals with essential hypertension and correlation with normotensives.
 

Author(s): N N Nwafor, A A Adeyekun, O A Adenike

Journal: Niger J Clin Pract. 2018 May;21(5):578-584.

 

Hypertension can secondarily involve the kidneys, and renal sonographic parameters can be used to indirectly assess renal function or status. Ultrasound is an inexpensive and safe modality for evaluating the kidneys. The purpose of this study was to sonographically assess renal parameters ...

Last Updated: 31 Dec 1969

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Effects of slow breathing rate on heart rate variability and arterial baroreflex sensitivity in essential hypertension.
 

Author(s): Changjun Li, Qinghua Chang, Jia Zhang, Wenshu Chai

Journal: Medicine (Baltimore). 2018 May;97(18):e0639.

 

This study is to investigate the effects of slow breathing on heart rate variability (HRV) and arterial baroreflex sensitivity in essential hypertension.We studied 60 patients with essential hypertension and 60 healthy controls. All subjects underwent controlled breathing at 8 and ...

Last Updated: 31 Dec 1969

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PubMed Article Results at NCBI: 1015 article(s)

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Essential hypertension" returned 93 free, full-text review articles on human participants. First 3 results:

Tianma Gouteng decoction for essential hypertension: Protocol for a systematic review and meta-analysis.
 

Author(s): Benjian Chen, Yuanping Wang, Zhuogen He, Dawei Wang, Xia Yan, Pingchang Xie

Journal: Medicine (Baltimore). 2018 Feb;97(8):e9972.

 

Essential hypertension is one of the most common chronic diseases, as well as one of the leading risk factors for cardio-cerebrovascular diseases. Tianma Gouteng decoction has been commonly used in clinical practice for patients with essential hypertension. It is important to update ...

Last Updated: 31 Dec 1969

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The Impact of Vitamin D in the Treatment of Essential Hypertension.
 

Author(s): Christian Legarth, Daniela Grimm, Markus Wehland, Johann Bauer, Marcus Krüger

Journal:

 

The aim of this review is to investigate, whether there is a possible link between vitamin D supplementation and the reduction of blood pressure in hypertensive patients. The renin-angiotensin-aldosterone system is known for being deeply involved in cardiovascular tonus and blood ...

Last Updated: 31 Dec 1969

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Inflammation, Autoimmunity, and Hypertension: The Essential Role of Tissue Transglutaminase.
 

Author(s): Chen Liu, Rodney E Kellems, Yang Xia

Journal: Am. J. Hypertens.. 2017 Aug;30(8):756-764.

 

Inflammatory cytokines cause hypertension when introduced into animals. Additional evidence indicates that cytokines induce the production of autoantibodies that activate the AT1 angiotensin receptor (AT1R). Extensive evidence shows that these autoantibodies, termed AT1-AA, contribute ...

Last Updated: 31 Dec 1969

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PubMed Review Results at NCBI: 93 review(s)

 
 
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Symptoms, Diagnosis, and Treatment

This information is provided by Genetics Home Reference.
https://ghr.nlm.nih.gov/condition/essential-pentosuria
https://ghr.nlm.nih.gov/condition/essential-thrombocythemia
https://ghr.nlm.nih.gov/condition/essential-tremor
https://ghr.nlm.nih.gov/condition/pulmonary-arterial-hypertension
https://ghr.nlm.nih.gov/condition/benign-essential-blepharospasm
https://ghr.nlm.nih.gov/gene/GOSR2
https://ghr.nlm.nih.gov/condition/pseudohypoaldosteronism-type-2
https://ghr.nlm.nih.gov/gene/NEDD4L
https://ghr.nlm.nih.gov/gene/AGT
https://ghr.nlm.nih.gov/condition/preeclampsia
https://ghr.nlm.nih.gov/gene/GNB3
https://ghr.nlm.nih.gov/condition/familial-hyperaldosteronism
https://ghr.nlm.nih.gov/condition/liddle-syndrome
https://ghr.nlm.nih.gov/gene/AGTR1
https://ghr.nlm.nih.gov/gene/NCF1
https://ghr.nlm.nih.gov/condition/cerebral-autosomal-recessive-arteriopathy-with-subcortical-infarcts-and-leukoencephalopathy
https://ghr.nlm.nih.gov/condition/congenital-adrenal-hyperplasia-due-to-11-beta-hydroxylase-deficiency
https://ghr.nlm.nih.gov/gene/BMPR2
https://ghr.nlm.nih.gov/gene/NR3C2
https://ghr.nlm.nih.gov/gene/WNK4
Full Results at Genetics Home Reference: 698 matches

There are currently no related results available in GeneReviews.

This information is provided by Genetic Testing Registry.
http://www.ncbi.nlm.nih.gov/gtr/conditions/C0085580
 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Renal Sympathetic Modification in Patients With Essential Hypertension
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 13 Jul 2017

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A Study to Evaluate the Efficacy and Safety of Combination Treatment of Fimasartan/Atorvastatin in Patients With Essential Hypertension and Dyslipidemia
 

Status: Recruiting

Condition Summary: Essential Hypertension, Dyslipidemia

 

Last Updated: 18 Jan 2018

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Efficacy and Safety of Arotinolol Hydrochloride on Morning Blood Pressure and Heart Rate
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 13 Oct 2016

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According to ClinicalTrials.gov there are currently 36 additional "open" studies for "Essential hypertension" (open studies are recruiting volunteers) and 461 "Essential hypertension" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance:
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Relief is when you and the right researcher find each other
Finding the right clinical trial for Essential hypertension can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Learn More