Esthesioneuroblastoma

Common Name(s)

Esthesioneuroblastoma

Esthesioneuroblastoma is a rare cancer of the upper part of the nasal cavity called the cribiform plate, which is a bone deep in the skull between the eyes, and above the ethmoid sinuses. It develops in nerve tissue associated with the sense of smell and can occur in people of any age. This cancer is very uncommon, accounting for 7 percent of all cancers of the nasal cavity and paranasal sinuses. Although it generally grows slowly, an esthesioneuroblastoma can sometimes grow very quickly. Fast-growing tumors can metastasize (spread) even many years after treatment of the initial tumor.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esthesioneuroblastoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esthesioneuroblastoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Esthesioneuroblastoma" returned 39 free, full-text research articles on human participants. First 3 results:

Prognostic significance of Kadish staging in esthesioneuroblastoma: An analysis of the National Cancer Database.
 

Author(s): Neeraja Konuthula, Alfred M Iloreta, Brett Miles, Ryan Rhome, Umut Ozbek, Eric M Genden, Marshall Posner, Krzysztof Misiukiewicz, Satish Govindaraj, Raj Shrivastava, Vishal Gupta, Richard L Bakst

Journal: Head Neck. 2017 10;39(10):1962-1968.

 

Given the rarity of esthesioneuroblastoma, it is difficult to validate a staging system. The purpose of this study was to investigate the utility of the Kadish staging system in esthesioneuroblastoma using the National Cancer Database (NCDB).

Last Updated: 31 Dec 1969

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Comprehensive Genomic Profiling of Esthesioneuroblastoma Reveals Additional Treatment Options.
 

Author(s): Laurie M Gay, Sungeun Kim, Kyle Fedorchak, Madappa Kundranda, Yazmin Odia, Chaitali Nangia, James Battiste, Gerardo Colon-Otero, Steven Powell, Jeffery Russell, Julia A Elvin, Jo-Anne Vergilio, James Suh, Siraj M Ali, Philip J Stephens, Vincent A Miller, Jeffrey S Ross

Journal: Oncologist. 2017 07;22(7):834-842.

 

Esthesioneuroblastoma (ENB), also known as olfactory neuroblastoma, is a rare malignant neoplasm of the olfactory mucosa. Despite surgical resection combined with radiotherapy and adjuvant chemotherapy, ENB often relapses with rapid progression. Current multimodality, nontargeted ...

Last Updated: 31 Dec 1969

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Optimal treatment and prognostic factors for esthesioneuroblastoma: retrospective analysis of 187 Chinese patients.
 

Author(s): Le Xiong, Xiao-Li Zeng, Chang-Kuo Guo, An-Wen Liu, Long Huang

Journal:

 

The standard treatment for esthesioneuroblastoma, a rare malignant nasal vault neoplasm, is not established.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Esthesioneuroblastoma" returned 11 free, full-text review articles on human participants. First 3 results:

Sphenoidal esthesioneuroblastoma treated with sequential chemo radiotherapy: a case report and review of the literature.
 

Author(s): Omar Abdel-Rahman, Khaled Kamal

Journal: J Cancer Res Ther. ;10(4):1101-3.

 

Esthesioneuroblastoma (ENB)-also known as olfactory neuroblastoma-originates primarily from the olfactory epithelium in the roof of the nasal cavity. We present here the 7th reported case of ENB arising from the sphenoidal sinus. We undertook a review of the case notes from the time ...

Last Updated: 31 Dec 1969

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Intraoperative hypertensive crisis due to a catecholamine-secreting esthesioneuroblastoma.
 

Author(s): Vafi Salmasi, Adam Schiavi, Zev A Binder, Jacob Ruzevick, Brent A Orr, Peter C Burger, Douglas W Ball, Ari M Blitz, Wayne M Koch, Masaru Ishii, Gary L Gallia

Journal: Head Neck. 2015 Jun;37(6):E74-80.

 

Although uncommon, esthesioneuroblastomas may produce clinically significant amounts of catecholamines.

Last Updated: 31 Dec 1969

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Atypical esthesioneuroblastoma invading oral cavity: a case report and review of the literature.
 

Author(s): Sandra Ventorin von Zeidler, Rafaela Guidi, Rita de Cássia Gonçalves Alencar, Renato Aguiar, Elismauro Francisco Mendonça, Aline Carvalho Batista, Rejane Faria Ribeiro-Rotta

Journal:

 

Esthesioneuroblastoma is an uncommon tumour of neuroectodermal origin. The authors describe a rare presentation of an atypical esthesioneuroblastoma invading oral cavity. The clinical presentation, aetiology, diagnosis, and management of this condition are discussed. The patient developed ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Esthesioneuroblastoma: Outcomes After Treatment
 

Status: Recruiting

Condition Summary: Esthesioneuroblastoma, Olfactory

 

Last Updated: 31 Mar 2017

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Intensity-Modulated or Proton Radiation Therapy for Sinonasal Malignancy
 

Status: Recruiting

Condition Summary: Adenoid Cystic Carcinoma; Squamous Cell Carcinoma; Sinonasal Carcinoma; Sinonasal Undifferentiated Carcinoma; Mucoepidermoid Carcinoma; Schneiderian Carcinoma; Myoepithelial Carcinoma; Esthesioneuroblastoma; Melanoma

 

Last Updated: 19 Sep 2018

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Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants
 

Status: Recruiting

Condition Summary: Head and Neck Cancer

 

Last Updated: 23 Jan 2018

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