Extragonadal Germ Cell Tumor

Common Name(s)

Extragonadal Germ Cell Tumor

Extragonadal germ cell tumors are rare tumors found in the reproductive organs (testicles in males, ovaries in females), that travel to other parts of the body outside of the ovary or testicle (e.g. brain, chest, abdomen, or tailbone). It is most commonly found in young males, age 20 or older. On risk factor for this condition is having Klinefelter syndrome. Symptoms of extragonadal cell tumors are varied and include chest pain, breathing problems, coughing, fever, headache, or trouble seeing or moving the eyes. Treatment depends on whether the size of the tumor, location of tumor, blood levels, the way the tumor responds to initial treatment, whether the tumor has spread, and whether the cancer has just been diagnosed or has come back. Treatment options include radiation therapy, chemotherapy, surgery, or possible clinical trials.

Source: Advocacy organizations associated with the condition.

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Advocacy and Support Organizations Health Questions Recommended Apps Scientific Literature Symptoms, Diagnosis, and Treatment Clinical Trial Information
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Extragonadal Germ Cell Tumor" for support, advocacy or research.

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Extragonadal Germ Cell Tumor" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
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Recommended Apps

Privately answer questions about your health. Let resources, you select, come to you

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

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Relief is when you and the right researcher find each other

Finding the right clinical trial for Extragonadal Germ Cell Tumor can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Extragonadal Germ Cell Tumor" returned 15 free, full-text research articles on human participants. First 3 results:

[A case of metachronal testicular tumor eight years after medical treatment of extragonadal germ cell tumor].
 

Author(s): Makoto Tanio, Yoshitaka Aoki, Hisato Kobayashi, Satoshi Yokoi, Hideaki Ito, Nobuyuki Oyama, Hironobu Akino, Osamu Yokoyama

Journal: Hinyokika Kiyo. 2015 Apr;61(4):173-6.

 

A 22-year-old man was admitted to our hospital complaining of a left cervical mass. Computed tomography (CT) showed multiple enlarged lymph nodes at the left cervical vein and para-aortic areas. Histological examination of a biopsy indicated an embryonal carcinoma. The levels of human ...

Last Updated: 31 Dec 1969

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Extragonadal germ cell tumor with the "burned-out" phenomenon presented a multiple retroperitoneal masses: a case report.
 

Author(s): Salih Budak, Orcun Celik, Hakan Turk, Tufan Suelozgen, Yusuf Ozlem Ilbey

Journal: Asian J. Androl.. ;17(1):163-4.

 

Last Updated: 31 Dec 1969

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Mixed extragonadal germ cell tumor arising from the prostate: a rare combination.
 

Author(s): Shu-Guang Liu, Bin Lei, Xue-Nong Li, Xiao-Dong Chen, Shuang Wang, Lin Zheng, Hai-Li Zhu, Pei-Xin Lin, Hong Shen

Journal: Asian J. Androl.. ;16(4):645-6.

 

Last Updated: 31 Dec 1969

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To view other free, full-text articles on human participants, please click on the link below.

PubMed Article Results at NCBI: 15 article(s)

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Extragonadal Germ Cell Tumor" returned 4 free, full-text review articles on human participants. First 3 results:

[A case of metachronous testicular tumor developing seven years after complete remission of retroperitoneal extragonadal germ cell tumor].
 

Author(s): Norihiko Kawamura, Keisuke Yamamoto, Iwao Yoshioka, Hiroshi Kiuchi, Sanehiro Momohara, Yasuhiro Matsuoka, Naotsugu Ichimaru, Norio Nonomura, Akihiko Okuyama, Tatsuya Kinoshita

Journal: Hinyokika Kiyo. 2009 Oct;55(10):635-8.

 

A 26-year-old man was admitted to our hospital with a chief complaint of left cervical lymphadenopathy. He was diagnosed as having seminoma by needle biopsy. Computed tomography revealed an aorto-caval retroperitoneal tumor. Levels of lactic deydrogenase, human beta-chorionic gonadotropin, ...

Last Updated: 31 Dec 1969

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Metachronous testicular tumor developing eight years after retroperitoneal extragonadal germ cell tumor.
 

Author(s): Yuta Yamada, Kyouichi Tomita, Tetsuya Fujimura, Hiroaki Nishimatsu, Takumi Takeuchi, Tadaichi Kitamura

Journal: Int. J. Urol.. 2008 Mar;15(3):267-9.

 

A 30 year-old man was admitted to our hospital with a chief complaint of left flank pain. Computed tomography revealed a retroperitoneal tumor. Levels of lactic dehydrogenase, human beta-chorionic gonadotropin, alpha-fetoprotein, DUPAN-2 and carbohydrate antigen 19-9 were elevated. ...

Last Updated: 31 Dec 1969

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[The result of VIP chemotherapy as an induction therapy in 6 patients with non-seminomatous extragonadal germ cell tumor].
 

Author(s): Mizuaki Sakura, Tetsurou Tsukamoto, Junji Yonese, Masayuki Nakaishi, Yuhei Ohkubo, Takuya Maezawa, Keita Takimoto, Iwao Fukui, Ken Nakagawa, Sakae Okumura, Yuichi Ishikawa, Nozomu Aoki

Journal: Nippon Hinyokika Gakkai Zasshi. 2004 Mar;95(3):634-7.

 

We treated 6 patients with non-seminomatous extragonadal germ cell tumor (NSEGCT) by VP-16 + ifosfamide + cisplatin (VIP) chemotherapy as an induction therapy to investigate the effectiveness and safety. Primary lesions were located at the mediastinum in 4 patients and the retroperitoneum ...

Last Updated: 31 Dec 1969

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To view other free, full-text review articles on human participants, please click on the link below.

PubMed Review Results at NCBI: 4 review(s)

 
 
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Symptoms, Diagnosis, and Treatment

This information is provided by Genetics Home Reference.
https://ghr.nlm.nih.gov/condition/desmoid-tumor
https://ghr.nlm.nih.gov/condition/lymphangioleiomyomatosis
https://ghr.nlm.nih.gov/condition/langerhans-cell-histiocytosis
https://ghr.nlm.nih.gov/condition/gastrointestinal-stromal-tumor
https://ghr.nlm.nih.gov/condition/gorlin-syndrome
https://ghr.nlm.nih.gov/condition/bap1-tumor-predisposition-syndrome
https://ghr.nlm.nih.gov/condition/rhabdoid-tumor-predisposition-syndrome
https://ghr.nlm.nih.gov/condition/hyperparathyroidism-jaw-tumor-syndrome
https://ghr.nlm.nih.gov/gene/MCFD2
https://ghr.nlm.nih.gov/condition/hyperphosphatemic-familial-tumoral-calcinosis
https://ghr.nlm.nih.gov/condition/head-and-neck-squamous-cell-carcinoma
https://ghr.nlm.nih.gov/condition/leydig-cell-hypoplasia
https://ghr.nlm.nih.gov/condition/sickle-cell-disease
https://ghr.nlm.nih.gov/primer/cell
https://ghr.nlm.nih.gov/primer/cellsdivide
https://ghr.nlm.nih.gov/gene/CDC73
https://ghr.nlm.nih.gov/gene/SAA1
https://ghr.nlm.nih.gov/condition/hereditary-leiomyomatosis-and-renal-cell-cancer
https://ghr.nlm.nih.gov/condition/nonsyndromic-paraganglioma
https://ghr.nlm.nih.gov/primer/genesanddivision
Full Results at Genetics Home Reference: 3735 matches

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors
 

Status: Recruiting

Condition Summary: Childhood Germ Cell Tumor; Ovarian Cancer; Teratoma

 

Last Updated: 12 Feb 2018

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Collecting and Storing Tissue From Young Patients With Cancer
 

Status: Recruiting

Condition Summary: Cancer

 

Last Updated: 27 Nov 2017

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Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors
 

Status: Recruiting

Condition Summary: Germ Cell Tumor; Teratoma; Choriocarcinoma; Germinoma; Mixed Germ Cell Tumor; Yolk Sac Tumor; Childhood Teratoma; Malignant Germ Cell Neoplasm; Extragonadal Seminoma; Non-seminomatous Germ Cell Tumor; Seminoma

 

Last Updated: 16 Jul 2018

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According to ClinicalTrials.gov there are currently 1 additional "open" studies for "Extragonadal Germ Cell Tumor" (open studies are recruiting volunteers) and 60 "Extragonadal Germ Cell Tumor" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance:
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Relief is when you and the right researcher find each other
Finding the right clinical trial for Extragonadal Germ Cell Tumor can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Learn More