FAMMM syndrome

Common Name(s)

FAMMM syndrome, Familial Atypical Multiple Mole Melanoma Syndrome , Dysplastic nevus syndrome, Familial melanoma, B-K mole syndrome

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "FAMMM syndrome" for support, advocacy or research.

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Melanoma International Foundation

The mission of the Melanoma International Foundation is to develop personalized strategies with patients so they may live longer, better lives.

Last Updated: 29 Jun 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "FAMMM syndrome" for support, advocacy or research.

Logo
Melanoma International Foundation

The mission of the Melanoma International Foundation is to develop personalized strategies with patients so they may live longer, better lives.

http://www.melanomainternational.org

Last Updated: 29 Jun 2015

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "FAMMM syndrome" returned 8 free, full-text research articles on human participants. First 3 results:

Undifferentiated carcinoma with osteoclastic giant cells (UCOCGC) of the pancreas associated with the familial atypical multiple mole melanoma syndrome (FAMMM).
 

Author(s): Jan-Bart M Koorstra, Anirban Maitra, Folkert H M Morsink, Paul Drillenburg, Fiebo J W ten Kate, Ralph H Hruban, Johan A Offerhaus

Journal: Am. J. Surg. Pathol.. 2008 Dec;32(12):1905-9.

 

The familial atypical multiple mole melanoma (FAMMM) syndrome is caused by a germline mutation of p16. More than 90% of the sporadic pancreatic carcinomas contain genetic alterations that inactivate p16. Patients with the FAMMM syndrome have an increased risk of developing pancreatic ...

Last Updated: 31 Dec 1969

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A locus linked to p16 modifies melanoma risk in Dutch familial atypical multiple mole melanoma (FAMMM) syndrome families.
 

Author(s): P A van der Velden, L A Sandkuijl, W Bergman, E T Hille, R R Frants, N A Gruis

Journal: Genome Res.. 1999 Jun;9(6):575-80.

 

The CDKN2A gene that encodes the cell cycle inhibitor p16 shows mutations in many but not all 9p21-linked melanoma families. Most Dutch melanoma families segregate for a unique founder mutation (p16-Leiden), encoding a truncated nonfunctional p16 protein. The highly variable risk ...

Last Updated: 31 Dec 1969

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Genetics of familial atypical multiple mole-melanoma (FAMMM) syndrome in The Netherlands: how far have we come?
 

Author(s): N A Gruis, P A Van der Velden, W Bergman, R R Frants

Journal: Bull Cancer. 1998 Jul;85(7):627-30.

 

By the genetic localization of the first melanoma susceptibility gene on chromosome 1p we thought that the puzzle on familial melanoma families would soon be solved. Now, almost fifteen years later we have learned that inherited melanoma is not a simple genetic disorder and that multiple ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "FAMMM syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study of IMMrayâ„¢ PanCan-d Test for Early Detection of Pancreatic Cancer in High-risk Groups
 

Status: Recruiting

Condition Summary: Pancreatic Ductal Adenocarcinoma; Familial Pancreatic Cancer; FAMMM - Familial Atypical Mole Malignant Melanoma Syndrome

 

Last Updated: 14 Nov 2018

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Pancreas Registry and High Risk Registry
 

Status: Recruiting

Condition Summary: Pancreas Cancer; Pancreatitis; Chronic Pancreatitis; Pancreatic Cyst; Family History of Pancreas Cancer; Genetic Mutations

 

Last Updated: 13 Feb 2018

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Pancreatic Cancer Early Detection Program
 

Status: Recruiting

Condition Summary: Pancreatic Cancer; Pancreas Cancer; Pancreatic Adenocarcinoma; Familial Pancreatic Cancer; BRCA 1/2; HNPCC; Lynch Syndrome; Hereditary Pancreatitis; FAMMM; Familial Atypical Multiple Mole Melanoma; Peutz Jeghers Syndrome

 

Last Updated: 12 May 2017

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