Factor VII Deficiency

Common Name(s)

Factor VII Deficiency

Factor VII deficiency is an autosomal recessive bleeding disorder showing variable severity (summary by {22:Millar et al., 2000}). {23:Perry (2002)} provided a comprehensive review of factor VII deficiency with a description of F7 polymorphisms, gene structure, and a summary of 120 mutations.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Factor VII Deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Factor VII Deficiency" returned 63 free, full-text research articles on human participants. First 3 results:

Two-incision laparoscopic appendectomy for a severe hemophilia A child patient with coagulation factor VII deficiency: Case report and review of literature.
 

Author(s): Jin Peng He, Jie Xiong Feng

Journal: Medicine (Baltimore). 2017 Oct;96(41):e8197.

 

The main complication of patients with severe hemophilia is recurrent bleeding events that usually affected musculoskeletal contractures. And replacement therapy methods were continuously improved to minimize adverse impacts brought by those complications. However, only several cases ...

Last Updated: 31 Dec 1969

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Differential functional readthrough over homozygous nonsense mutations contributes to the bleeding phenotype in coagulation factor VII deficiency.
 

Author(s): A Branchini, M Ferrarese, S Lombardi, R Mari, F Bernardi, M Pinotti

Journal: J. Thromb. Haemost.. 2016 10;14(10):1994-2000.

 

Essentials Potentially null homozygous Factor(F)7 nonsense mutations are associated to variable bleeding symptoms. Readthrough of p.Ser112X (life-threatening) and p.Cys132X (moderate) stop codons was investigated. Readthrough-mediated insertion of wild-type or tolerated residues produce ...

Last Updated: 31 Dec 1969

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Lower extremity compartment syndrome in the setting of iliofemoral deep vein thrombosis, phlegmasia cerulea dolens and factor VII deficiency.
 

Author(s): Wahid Abdul, Ben Hickey, Chris Wilson

Journal:

 

Acute compartment syndrome requires urgent fasciotomies to prevent irreversible muscle damage. We present a case of massive iliofemoral deep vein thrombosis (DVT) presenting as acute compartment syndrome. A healthy 21-year-old man presented with a 2-day history of worsening left leg ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Factor VII Deficiency" returned 3 free, full-text review articles on human participants. First 3 results:

Is prophylaxis required for delivery in women with factor VII deficiency?
 

Author(s): L M Baumann Kreuziger, Colleen T Morton, Mark T Reding

Journal: Haemophilia. 2013 Nov;19(6):827-32.

 

Factor VII (fVII) deficiency is a rare congenital bleeding disorder in which fVII activity level and bleeding tendency do not completely correlate. Pregnancy and delivery present a significant haemostatic challenge to women with fVII deficiency. Treatment with recombinant factor VIIa ...

Last Updated: 31 Dec 1969

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Factor VII deficiency and pregnancy: a case report and review of literature.
 

Author(s): Syed Mohammad Asad Zaidi, Rahat Najam Qureshi, Salman Naseem Adil

Journal: J Pak Med Assoc. 2010 Feb;60(2):136-8.

 

Factor VII deficiency is one of the 'rare inherited disorders of coagulation.' Few cases of Factor VII deficiency have been reported during pregnancy, a state which could potentially cause fatal haemorrhage. Here we report a case of a pregnant lady with a history of heavy menorrhagia ...

Last Updated: 31 Dec 1969

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Factor VII deficiency and developmental abnormalities in a patient with partial monosomy of 13q and trisomy of 16p: case report and review of the literature.
 

Author(s): Brian P Brooks, Jeanne M Meck, Bassem R Haddad, Claude Bendavid, Delphine Blain, Jeffrey A Toretsky

Journal:

 

Unbalanced chromosomal translocations may present with a variety of clinical and laboratory findings and provide insight into the functions of genes on the involved chromosomal segments.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 25 Jun 2018

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