Fallopian Tube Cancer

Common Name(s)

Fallopian Tube Cancer

Fallopian tube cancer is a very rare form of cancer with only 1,500 to 2,000 cases reported each year in the United States. However, a number of cancers start in other parts of the body and spread to the fallopian tubes, called secondary fallopian tube cancers. Some symptoms include abnormal vaginal bleeding, abnormal vaginal discharge, abdominal pain, and feeling a mass in the abdomen (belly) or pelvis. A female pelvic exam can assist in the diagnosis of this condition by evaluating the size and shape of the uterus, vagina, ovaries, fallopian tubes, bladder and rectum. A blood test can also be performed to check the levels of a certain protein called CA125, which may be used to diagnose fallopian tube cancer. Treatment usually involves surgery and chemotherapy, depending on age, desire to have children, and the type and stage of the tumor.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fallopian Tube Cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fallopian Tube Cancer" returned 70 free, full-text research articles on human participants. First 3 results:

Progesterone Prevents High-Grade Serous Ovarian Cancer by Inducing Necroptosis of p53-Defective Fallopian Tube Epithelial Cells.
 

Author(s): Na-Yiyuan Wu, Hsuan-Shun Huang, Tung Hui Chao, Hsien Ming Chou, Chao Fang, Chong-Zhen Qin, Chueh-Yu Lin, Tang-Yuan Chu, Hong Hao Zhou

Journal: Cell Rep. 2017 Mar;18(11):2557-2565.

 

High-grade serous ovarian carcinoma (HGSOC) originates mainly from the fallopian tube (FT) epithelium and always carries early TP53 mutations. We previously reported that tumors initiate in the FT fimbria epithelium because of apoptotic failure and the expansion of cells with DNA ...

Last Updated: 31 Dec 1969

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Safety and Activity of Mirvetuximab Soravtansine (IMGN853), a Folate Receptor Alpha-Targeting Antibody-Drug Conjugate, in Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer: A Phase I Expansion Study.
 

Author(s): Kathleen N Moore, Lainie P Martin, David M O'Malley, Ursula A Matulonis, Jason A Konner, Raymond P Perez, Todd M Bauer, Rodrigo Ruiz-Soto, Michael J Birrer

Journal: J. Clin. Oncol.. 2017 Apr;35(10):1112-1118.

 

Purpose This phase I expansion cohort study evaluated the safety and clinical activity of mirvetuximab soravtansine (IMGN853), an antibody-drug conjugate consisting of a humanized anti-folate receptor alpha (FRĪ±) monoclonal antibody linked to the tubulin-disrupting maytansinoid DM4, ...

Last Updated: 31 Dec 1969

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Genomics of Ovarian Cancer Progression Reveals Diverse Metastatic Trajectories Including Intraepithelial Metastasis to the Fallopian Tube.
 

Author(s): Mark A Eckert, Shawn Pan, Kyle M Hernandez, Rachel M Loth, Jorge Andrade, Samuel L Volchenboum, Pieter Faber, Anthony Montag, Ricardo Lastra, Marcus E Peter, S Diane Yamada, Ernst Lengyel

Journal: Cancer Discov. 2016 12;6(12):1342-1351.

 

Accumulating evidence has supported the fallopian tube rather than the ovary as the origin for high-grade serous ovarian cancer (HGSOC). To understand the relationship between putative precursor lesions and metastatic tumors, we performed whole-exome sequencing on specimens from eight ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fallopian Tube Cancer" returned 7 free, full-text review articles on human participants. First 3 results:

Data set for reporting of ovary, fallopian tube and primary peritoneal carcinoma: recommendations from the International Collaboration on Cancer Reporting (ICCR).
 

Author(s): W Glenn McCluggage, Meagan J Judge, Blaise A Clarke, Ben Davidson, C Blake Gilks, Harry Hollema, Jonathan A Ledermann, Xavier Matias-Guiu, Yoshiki Mikami, Colin J R Stewart, Russell Vang, Lynn Hirschowitz,

Journal: Mod. Pathol.. 2015 Aug;28(8):1101-22.

 

A comprehensive pathological report is essential for optimal patient management, cancer staging and prognostication. In many countries, proforma reports are used but these vary in their content. The International Collaboration on Cancer Reporting (ICCR) is an alliance formed by the ...

Last Updated: 31 Dec 1969

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FIGO's staging classification for cancer of the ovary, fallopian tube, and peritoneum: abridged republication.
 

Author(s): Jaime Prat,

Journal: J Gynecol Oncol. 2015 Apr;26(2):87-9.

 

Last Updated: 31 Dec 1969

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Precursors of ovarian cancer in the fallopian tube: serous tubal intraepithelial carcinoma--an update.
 

Author(s): Felix Zeppernick, Ivo Meinhold-Heerlein, Ie-Ming Shih

Journal: J. Obstet. Gynaecol. Res.. 2015 Jan;41(1):6-11.

 

Ovarian tumors comprise a wide variety of entities. The largest group, epithelial ovarian carcinoma, can be classified into two main groups, type I and type II tumors. Recent advances in the understanding of ovarian cancer development have resulted in the finding of 'serous tubal ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

p53 Gene in Treatment of Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer
 

Status: Not yet recruiting

Condition Summary: Ovarian Epithelial Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer

 

Last Updated: 30 Apr 2015

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Veliparib and Floxuridine in Treating Patients With Metastatic Epithelial Ovarian, Primary Peritoneal Cavity, or Fallopian Tube Cancer
 

Status: Recruiting

Condition Summary: Stage IV Fallopian Tube Cancer; Stage IV Ovarian Cancer; Stage IV Primary Peritoneal Cancer

 

Last Updated: 30 Jun 2017

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