Fibromuscular Dysplasia

Common Name(s)

Fibromuscular Dysplasia

Fibromuscular dysplasia (FMD) is the abnormal development or growth of cells in the walls of arteries that can cause the vessels to narrow or bulge. The carotid arteries, which pass through the neck and supply blood to the brain, are commonly affected. Arteries within the brain and kidneys can also be affected. Narrowing and enlarging of arteries can block or reduce blood flow to the brain, causing a stroke. Some patients experience no symptoms of the disease while others may have high blood pressure, dizziness or vertigo, chronic headache, intracranial aneurysm, ringing in the ears, weakness or numbness in the face, neck pain, or changes in vision. FMD is most often seen in people age 25 to 50 years and affects women more often than men. More than one family member may be affected by the disease. The cause of FMD is unknown. Treatment is based on the arteries affected and the progression and severity of the disease.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fibromuscular Dysplasia" for support, advocacy or research.

Fibromuscular Dysplasia Society of America

The Fibromuscular Dysplasia Society of America is a voluntary health organization dedicated to improving the lives of those afflicted with Fibromuscular Dysplasia by raising awareness and developing funds to promote research towards new medical treatments and diagnostic tools.

Last Updated: 15 Jan 2014

View Details
FMD Chat

FMD Chat is an international nonprofit organization dedicated to supporting those affected by fibromuscular dysplasia including patients, family members, caregivers, and healthcare professionals.

Last Updated: 7 May 2014

View Details
Midwest Women's Vascular Advocates

Our mission is to support and educate women affected by Fibromsucular Dysplasia and non-inflammatory vascular disease.

Last Updated: 20 Jan 2011

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fibromuscular Dysplasia" for support, advocacy or research.

Fibromuscular Dysplasia Society of America

The Fibromuscular Dysplasia Society of America is a voluntary health organization dedicated to improving the lives of those afflicted with Fibromuscular Dysplasia by raising awareness and developing funds to promote research towards new medical treatments and diagnostic tools.

http://www.fmdsa.org

Last Updated: 15 Jan 2014

View Details
FMD Chat

FMD Chat is an international nonprofit organization dedicated to supporting those affected by fibromuscular dysplasia including patients, family members, caregivers, and healthcare professionals.

http://www.fmdchat.org

Last Updated: 7 May 2014

View Details
Midwest Women's Vascular Advocates

Our mission is to support and educate women affected by Fibromsucular Dysplasia and non-inflammatory vascular disease.

www.mwva.org

Last Updated: 20 Jan 2011

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

FMD Chat Readings & Resources

Learn more about fibromuscular dysplasia, systems impacted by the disease, general health, advance planning, caregiving, and international rare disease organizations.

Uploaded By: FMD Chat

Updated 13 Dec 2012

Go To URL
RareConnect's International FMD Community

Connect with patients around the world via RareConnect and the fibromuscular dysplasia community that FMD Chat helped develop. Translation services are available so that users may better share information.

Uploaded By: FMD Chat

Updated 13 Dec 2012

Go To URL
Patient Support Information

A list of resources for patients diagnosed with FMD.

Updated 25 Mar 2013

Go To URL
FMD Clinics

A list of FMD Clinics in the United States

Updated 25 Mar 2013

Go To URL
FMD Patient Stories

A list of patients stories including children , men, multiple family members and pregnancy and FMD.

Updated 25 Mar 2013

Go To URL
Centers participating in the FMD Patient Registry

A List of 12 centers participating in the FMD Patient Registry.

Updated 25 Mar 2013

Go To URL
Educational Video's

Video's on fibromuscular dysplasia

Updated 25 Mar 2013

Go To URL
FMD Web Chat Transcripts

Web chat transcripts. Dr Heather Gornik of the Cleveland Clinic and Pam Mace Executive Director of FMDSA answer patient questions

Updated 15 Jan 2014

Go To URL
FMD Emergency Wallet Card/PT Toolbox

FMD emergency wallet card for patients, medication card and letter for your physician

Updated 15 Jan 2014

Go To URL
FMD Research

A list of research studies for patients who are interested in participating

Updated 15 Jan 2014

Go To URL
Smart Patients

Smart Patients is available to anyone who has access to the internet, and its community has a medically-influenced approach to information sharing. FMD Chat's Smart Patients community is for patients and caregivers.

Uploaded By: FMD Chat

Updated 7 May 2014

Go To URL

Updated 7 May 2014

Open Doc
 
 
Top

Blogs

FMDSA Facebook Page

Where articles and current news is posted daily.

Updated 8 Oct 2012

Go To URL
FMDSA Inspire Support group

On line support group community for patients with Fibromuscular Dysplasia (FMD)

Updated 25 Mar 2013

Go To URL
 
 
Top

Insurance Issues

FMD Chat NeedyMeds Prescription Drug Discount Card

The drug discount card is not an insurance plan, but provides patients with discounted rates on prescriptions. When this card is presented with a valid prescription to a pharmacist, up to an 80 percent discount may be provided.

Uploaded by Advocacy Organization: FMD Chat

Updated 13 Dec 2012

Go To URL
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fibromuscular Dysplasia" returned 126 free, full-text research articles on human participants. First 3 results:

Missense mutations in COL4A5 or COL4A6 genes may cause cerebrovascular fibromuscular dysplasia: Case report and literature review.
 

Author(s): Xiaojuan Wang, Wei Li, Ke Wei, Rui Xiao, Juntao Wang, Haichang Ma, Lingzhi Qin, Wenjun Shao, Chunyang Li

Journal: Medicine (Baltimore). 2018 Jul;97(30):e11538.

 

Fibromuscular dysplasia (FMD) is a rare and controversial disease that is seldom associated with genes. Here, we report the discovery of 2 missense mutations in COL4A5 and COL4A6 that may be risk factors for causing cerebrovascular FMD. We performed high-throughput sequencing on a ...

Last Updated: 31 Dec 1969

Go To URL
Fibromuscular Dysplasia: Another Paradigm Shift in Renovascular Hypertension?
 

Author(s): Katsutoshi Takahashi, Toshiyuki Unno

Journal: Intern. Med.. 2018 09;57(18):2605-2606.

 

Last Updated: 31 Dec 1969

Go To URL
A rare case report of bilateral common and internal iliac arterial fibromuscular dysplasia: Coexisted dissection, aneurysm, and stenosis.
 

Author(s): Luyun Fan, Wenjun Ma, Huimin Zhang, Jun Cai

Journal: Medicine (Baltimore). 2017 Dec;96(50):e8896.

 

Iliac arterial fibromuscular dysplasia (FMD) was rarely reported and its demographic, clinical, and imaging features have not been precisely described resulting in uncertain therapeutic methods.

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fibromuscular Dysplasia" returned 15 free, full-text review articles on human participants. First 3 results:

Genomics of Fibromuscular Dysplasia.
 

Author(s): Silvia Di Monaco, Adrien Georges, Jean-Philippe Lengelé, Miikka Vikkula, Alexandre Persu

Journal:

 

Fibromuscular Dysplasia (FMD) is “an idiopathic, segmental, non-atherosclerotic and non-inflammatory disease of the musculature of arterial walls, leading to stenosis of small and medium-sized arteries” (Persu, et al; 2014). FMD can lead to hypertension, arterial dissections, ...

Last Updated: 31 Dec 1969

Go To URL
Fibromuscular dysplasia: Advances in understanding and management.
 

Author(s): Ellen K Brinza, Heather L Gornik

Journal: Cleve Clin J Med. 2016 Nov;83(11 Suppl 2):S45-S51.

 

Several key findings in recent years have reshaped our understanding of fibromuscular dysplasia (FMD), an uncommon nonatherosclerotic disease of medium-sized arteries that affects mainly women. While the true prevalence of this disease remains unknown, studies suggest that more people ...

Last Updated: 31 Dec 1969

Go To URL
Renal Fibromuscular Dysplasia: A Not So Common Entity of Secondary Hypertension.
 

Author(s): Elias A Sanidas, Maria Seferou, Dimitris P Papadopoulos, Anastasios Makris, Nora A Viniou, Vasiliki Chantziara, Vasiliki Cennimata, Vasilios Papademetriou

Journal: J Clin Hypertens (Greenwich). 2016 Mar;18(3):240-6.

 

Fibromuscular dysplasia is a rare noninflammatory vascular disease characterized by nonatheroslerotic stenosis predominantly seen in young women, whereas the majority of cases involve the renal arteries causing secondary hypertension. Most noninvasive screening tests are not quite ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Assessment of Renal Artery Fibromuscular Dysplasia: From Diagnosis to Treatment
 

Status: Recruiting

Condition Summary: Renal Artery Fibromuscular Dysplasia

 

Last Updated: 6 Jul 2016

Go to URL
Study of Arterial Properties by Ultra-high Frequency Ultrasound in Fibromuscular Dysplasia and Vascular Ehlers-Danlos Syndrome
 

Status: Not yet recruiting

Condition Summary: Ehlers-Danlos Syndrome; Fibromuscular Dysplasia

 

Last Updated: 20 Jul 2018

Go to URL
Defining the Basis of Fibromuscular Dysplasia (FMD)
 

Status: Recruiting

Condition Summary: Fibromuscular Dysplasia; Spontaneous Coronary Artery Dissection; Cervical Artery Dissection

 

Last Updated: 13 Jun 2018

Go to URL