Frey's Syndrome

Common Name(s)

Frey's Syndrome

Frey's Syndrome is a rare neurological disorder that results from injury or surgery near the parotid glands (which manufacture saliva), damaging the facial nerve. The parotid glands are the largest salivary glands and are located on the side of the face below and in front of the ear. This syndrome is characterized by flushing or sweating on one side of the face when certain foods are consumed. The symptoms usually are mild and well tolerated by most individuals. Relief from symptoms may require treatment in some cases.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Frey's Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Frey's Syndrome" returned 19 free, full-text research articles on human participants. First 3 results:

Efficacy and safety of botulinum toxin type A for treatment of Frey's syndrome: evidence from 22 published articles.
 

Author(s): Shang Xie, Kan Wang, Tao Xu, Xue-Sheng Guo, Xiao-Feng Shan, Zhi-Gang Cai

Journal: Cancer Med. 2015 Nov;4(11):1639-50.

 

Frey's syndrome (FS) is an unavoidable sequela following the surgery of the parotid gland. Although several treatment methods are available, their efficacy is short term or accompanied by unacceptable complications. In the past two decades, botulinum toxin type A (BTXA) has been widely ...

Last Updated: 31 Dec 1969

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A case of Frey's syndrome.
 

Author(s): Duriye Deniz Demirseren, Gülşen Akoglu, Selma Emre, Ahmet Metin

Journal: Indian J Dermatol Venereol Leprol. ;80(1):88-9.

 

Last Updated: 31 Dec 1969

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Use of irradiate animal pericardium membrane for prevention of Frey's syndrome after parotidectomy.
 

Author(s): P Gennaro, P Di Curzio, V Mitro, A Facchini, G Saponaro, F Cascino, G Amodeo, G Gabriele, C Ungari

Journal: Eur Rev Med Pharmacol Sci. 2013 Feb;17(4):548-51.

 

Frey syndrome is a common complication that appears few months after parotid surgery with flushing and sweating of the parotid-temporal area during mastication. It presumably originates from an aberrant nervous regeneration in which the parasympathetic fibers of the parotid gland ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Frey's Syndrome" returned 2 free, full-text review articles on human participants. First 3 results:

Infantile Frey's syndrome.
 

Author(s): Brittny N Tillman, Marci M Lesperance, Jennifer V Brinkmeier

Journal: Int. J. Pediatr. Otorhinolaryngol.. 2015 Jun;79(6):929-31.

 

Frey's syndrome in children is rare and often erroneously attributed to food allergy. Here we describe a case of Frey's syndrome in an infant and provide a review of the literature. Awareness of this condition is important for the Otolaryngologist in order to avoid unnecessary medical ...

Last Updated: 31 Dec 1969

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Sternocleidomastoid muscle flap in preventing Frey's syndrome after parotidectomy: a systematic review.
 

Author(s): Alvaro Sanabria, Luiz P Kowalski, Patrick J Bradley, Dana M Hartl, Carol R Bradford, Remco de Bree, Alessandra Rinaldo, Alfio Ferlito

Journal: Head Neck. 2012 Apr;34(4):589-98.

 

Parotidectomy is a common procedure and Frey's syndrome (gustatory sweating) is a common side effect. The current literature was assessed concerning the effectiveness of the sternocleidomastoid muscle (SCM) flap to prevent Frey's syndrome after parotidectomy.

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.