Frontal fibrosing alopecia

Common Name(s)

Frontal fibrosing alopecia

Frontal fibrosing alopecia (FFA) is a form of lichen planus follicularis that is characterized primarily by slowly progressive hair loss (alopecia) and scarring on the scalp near the forehead. In some cases, the eyebrows, eye lashes and/or other parts of the body may be involved, as well. Although it has been suggested that FFA may be due to hormonal changes or an autoimmune response, the exact cause of this condition is not yet known. There is currently no cure for FFA; however, treatment with certain types of medications may stop or slow hair loss in some cases.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Frontal fibrosing alopecia" for support, advocacy or research.

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Cicatricial Alopecia Research Foundation

Cicatricial Alopecia Research Foundation (CARF) is a nonprofit public charities organization and the world's only voice for patients with cicatricial alopecia. MISSON: • Fund research to find effective treatments, and ultimately a cure • Support patient education and advocacy • Raise public awareness about the disease

Last Updated: 12 Sep 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Frontal fibrosing alopecia" for support, advocacy or research.

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Cicatricial Alopecia Research Foundation

Cicatricial Alopecia Research Foundation (CARF) is a nonprofit public charities organization and the world's only voice for patients with cicatricial alopecia. MISSON: • Fund research to find effective treatments, and ultimately a cure • Support patient education and advocacy • Raise public awareness about the disease

http://www.carfintl.org

Last Updated: 12 Sep 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Frontal fibrosing alopecia" returned 13 free, full-text research articles on human participants. First 3 results:

Coexistence of chronic cutaneous lupus erythematosus and frontal fibrosing alopecia.
 

Author(s): Luciana Lima do Nascimento, Milvia Maria Simões E Silva Enokihara, Mônica Ribeiro de Azevedo Vasconcellos

Journal: An Bras Dermatol. 2018 Mar;93(2):274-276.

 

Lupus erythemathosus is a chronic, relapsing disease with acute, subacute, and chronic lesions. Effluvium telogen occurs in the setting of systemic activity of the disease, and cicatricial alopecia results from discoid lesionsin on the scalp. Other types of alopecia, like alopecia ...

Last Updated: 31 Dec 1969

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Piccardi-Lassueur-Graham-Little syndrome associated with frontal fibrosing alopecia.
 

Author(s): Andrea Alejandra Catalán Griffiths, Maribel Iglesias Sancho, Ana Iglesias Plaza

Journal: An Bras Dermatol. ;92(6):867-869.

 

Piccardi-Lassueur-Graham-Little syndrome is a rare entity characterized by progressive scarring alopecia of the scalp and keratotic papules on hairless skin, associated with non-scarring alopecia in the axilla and pubic area or lichen planus lesions. We describe the case of a 70-year-old ...

Last Updated: 31 Dec 1969

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Frontal fibrosing alopecia and lichen planus pigmentosus: diagnosis and therapeutic challenge.
 

Author(s): Fabiane Andrade Mulinari-Brenner, Marina Riedi Guilherme, Murilo Calvo Peretti, Betina Werner

Journal: An Bras Dermatol. 2017 ;92(5 Suppl 1):79-81.

 

Frontal fibrosing alopecia is a variant of lichen planopilaris with marginal progressive hair loss on the scalp, eyebrows and axillae. We report a case of frontal fibrosing alopecia and lichen planus pigmentosus in a postmenopausal woman, that started with alopecia on the eyebrows ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Frontal fibrosing alopecia" returned 3 free, full-text review articles on human participants. First 3 results:

DHEA and frontal fibrosing alopecia: molecular and physiopathological mechanisms.
 

Author(s): Neide Kalil Gaspar

Journal: An Bras Dermatol. ;91(6):776-780.

 

The transforming growth factor-beta 1 (TGFβ1) promotes fibrosis, differentiating epithelial cells and quiescent fibroblasts into myofibroblasts and increasing expression of extracellular matrix. Recent investigations have shown that PPAR (peroxisome proliferator-activated receptor*) ...

Last Updated: 31 Dec 1969

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[Frontal fibrosing alopecia (FFA): Report on four cases and review of the literature].
 

Author(s): Miguel Ángel Cardona-Hernández, Fermín Jurado-Santa Cruz, Gisela Navarrete-Franco, Edna Azucena Gaxiola-Álvarez, Mónica Elizabeth de la Torre-García, Ana Luisa Cabrera-Pérez

Journal: Gac Med Mex. ;152(1):103-10.

 

Frontal fibrosing alopecia was recently described by Kossard, et al. as a progressive symmetrical recession of the frontal-temporal-parietal hairline affecting particularly postmenopausal women. Besides affecting the scalp, there are some cases in the literature with partial or total ...

Last Updated: 31 Dec 1969

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Frontal fibrosing alopecia: case report.
 

Author(s): Débora Nathália Smidarle, Mauren Seidl, Roberta Castilhos da Silva

Journal: An Bras Dermatol. ;85(6):879-82.

 

Frontal fibrosing alopecia is a kind of progressive and frequently irreversible cicatricial alopecia marked by a lichenoid infiltrate in histology. Since its first description, in 1994, in Australia, some cases have been documented all over the world. The article reports, for the ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Platelet Rich Plasma for Frontal Fibrosing Alopecia
 

Status: Not yet recruiting

Condition Summary: Frontal Fibrosing Alopecia

 

Last Updated: 8 Mar 2018

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Trial Evaluating the Efficacy of Apremilast for the Treatment of Frontal Fibrosing Alopecia
 

Status: Recruiting

Condition Summary: Frontal Fibrosing Alopecia

 

Last Updated: 12 Jul 2018

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Design and Validation of a New Assessment Tool for Lichen Planopilaris
 

Status: Recruiting

Condition Summary: Lichen Planopilaris of Scalp; Lichen Plano-Pilaris; Lichen Planopilaris; Frontal Fibrosing Alopecia

 

Last Updated: 30 Mar 2018

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