Germinoma

Common Name(s)

Germinoma

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Germinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Germinoma" returned 79 free, full-text research articles on human participants. First 3 results:

PD-1/PD-L1 expression in a series of intracranial germinoma and its association with Foxp3+ and CD8+ infiltrating lymphocytes.
 

Author(s): Bin Liu, Yoshiki Arakawa, Ryuta Yokogawa, Shinya Tokunaga, Yukinori Terada, Daiki Murata, Yasuzumi Matsui, Ko-Ichi Fujimoto, Nobuyuki Fukui, Masahiro Tanji, Yohei Mineharu, Sachiko Minamiguchi, Susumu Miyamoto

Journal:

 

One histopathological characteristic of intracranial germinoma is abundant tumor-infiltrating lymphocytes (TILs) showing a two-cell pattern with large undifferentiated tumor cells. The programmed cell death 1 (PD-1)/programmed cell death 1 ligand (PD-L) axis has recently been recognized ...

Last Updated: 31 Dec 1969

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Radiographic occult cerebellar germinoma presenting with progressive ataxia and cranial nerve palsy.
 

Author(s): Noriaki Minami, Kazuhiro Tanaka, Hidehito Kimura, Takanori Hirose, Tatsuya Mori, Masahiro Maeyama, Hiroaki Sekiya, Takeshi Uenaka, Satoshi Nakamizo, Hiroaki Nagashima, Katsu Mizukawa, Tomoo Itoh, Takashi Sasayama, Eiji Kohmura

Journal:

 

Although the usefulness of susceptibility-weighted imaging (SWI) for detecting basal ganglia germinoma has been reported, the technique is not widely used. We recently encountered an unusual case of primary cerebellar germinoma, presenting with progressive ataxia and cranial nerve ...

Last Updated: 31 Dec 1969

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Can mixed pure hepatocellular carcinoma and germinoma arise together in the brain?
 

Author(s): Lu-Jen Chen, I-Chun Lai, Tai-Tong Wong, Shih-Chieh Lin, Donald Ming-Tak Ho, Kai-Ping Chang, Wan-Yuo Guo, Sang-Hue Yen, Ming-Teh Chen, Yi-Wei Chen

Journal: J Chin Med Assoc. 2015 Sep;78(9):562-6.

 

Intracranial germ-cell tumors (GCTs) represent 10-15% of all pediatric brain tumors in East Asia. There is a wide histopathological spectrum of intracranial GCTs. Germinomas and nongerminomatous GCTs are the two major classifications. It is difficult to distinguish different subtypes ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Germinoma" returned 12 free, full-text review articles on human participants. First 3 results:

Management of CNS germinoma.
 

Author(s): Diana S Osorio, Jeffrey C Allen

Journal: CNS Oncol. 2015 ;4(4):273-9.

 

The following is a general overview of the management of CNS germinomas. Over the last 35 years, CNS germinomas have become one of the pediatric brain tumors with the best outcomes with a greater than 85% overall survival over 5 years. This is in part due to the fact that germinomas ...

Last Updated: 31 Dec 1969

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Germinoma in two brothers: case report.
 

Author(s): Naoki Nitta, Tadateru Fukami, Kazuhiko Nozaki

Journal: Neurol. Med. Chir. (Tokyo). 2013 ;53(10):703-6.

 

We present a third reported case of intracranial germinomas occurring in two brothers. They underwent chemotherapy and radiotherapy after biopsy and are doing well for 10 years and 20 months, respectively. The pertinent literatures are reviewed, and the possible role of heredity in ...

Last Updated: 31 Dec 1969

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Effective radiotherapy cured cauda equina syndrome caused by remitted intracranial germinoma depositing.
 

Author(s): Ying-Chun Lu, Hueng-Chuen Fan, Hong-Wei Gao, Chang-Ming Chen, Yee-Min Jen, Shin-Nan Cheng, Shyi-Jou Chen

Journal: Pediatr Neonatol. 2012 Oct;53(5):315-9.

 

Cauda equina syndrome (CES) in children is very rare and can permanently disable. A remitted intracranial germinoma depositing on the spinal cord, leading to CES, has never been reported. We discuss the case of a 10-year-old girl who presented with sudden ataxia, low back pain, sensory ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
 

Status: Recruiting

Condition Summary: Diffuse Intrinsic Pontine Glioma; PNET; Ependymoma; Germinoma; Medulloblastoma

 

Last Updated: 8 Aug 2018

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Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors
 

Status: Recruiting

Condition Summary: Germ Cell Tumor; Teratoma; Choriocarcinoma; Germinoma; Mixed Germ Cell Tumor; Yolk Sac Tumor; Childhood Teratoma; Malignant Germ Cell Neoplasm; Extragonadal Seminoma; Non-seminomatous Germ Cell Tumor; Seminoma

 

Last Updated: 6 Aug 2018

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Therapeutic Strategy Guided by PET-TDM for Patients With Seminoma
 

Status: Recruiting

Condition Summary: Seminoma

 

Last Updated: 8 Jun 2016

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