HIV

Common Name(s)

HIV

Human immunodeficiency virus or HIV is a viral infection of the immune system. Acquired immune deficiency disease (AIDS) is the umbrella term used to describe the final stage of an HIV infection. HIV is a sexually transmitted infection, but HIV can also be transmitted by contaminated hypodermic needles and blood transfusions, as well as from mother to child during pregnancy, delivery, and breastfeeding. Early symptoms of an HIV infection include fever, rash, night sweats, headaches, sore throat, fatigue, and a general feeling of having the flu, but many individuals who are HIV positive do not have any symptoms. This is because the virus has a latency stage, also known as the chronic phase. The virus can lay dormant inside your cells for years. HIV is a human retrovirus. The term retrovirus means that the virus can replicate inside a human cell. The retrovirus is an RNA virus; it converts itself into DNA and inserts itself into the cell’s genome. Once it is part of the cell’s genetic code, the virus is then produced by the cell’s replication machinery. Once enough of the virus has been produced within the cell, the cell dies and releases the virus into the body. HIV attacks the cells of your immune system, specifically the CD4 cells. CD4 cells include T helper cells, monocytes, macrophages, and dendritic cells. The virus decreases the number CD4 cells in the body, therefore diminishing the body’s ability to fight infection. Once your number of CD4 cells has fallen below 200 per cubic millimeter of blood, you will be diagnosed with AIDS. There is no cure for an HIV infection or AIDS. There are treatments that can suppress the HIV virus and help to slow the progression of the disease.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HIV" for support, advocacy or research.

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

Last Updated: 11 Jul 2016

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The Well Project

The Well Project is a non-profit organization whose mission is to change the course of the HIV/AIDS pandemic through a unique and comprehensive focus on women and girls. The Well Project advocates that every woman and girl should have access to quality, up-to-date information about HIV/AIDS.

Last Updated: 20 May 2014

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General Support Organizations

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How do you compare to others with this condition?

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Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HIV" for support, advocacy or research.

Logo
The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

http://www.thestdproject.com/

Last Updated: 11 Jul 2016

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The Well Project

The Well Project is a non-profit organization whose mission is to change the course of the HIV/AIDS pandemic through a unique and comprehensive focus on women and girls. The Well Project advocates that every woman and girl should have access to quality, up-to-date information about HIV/AIDS.

http://www.thewellproject.org/

Last Updated: 20 May 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "HIV" returned 43622 free, full-text research articles on human participants. First 3 results:

Frail and pre-frail phenotype is associated with pain in older HIV-infected patients.
 

Author(s): Nathalie Petit, Patricia Enel, Isabelle Ravaux, Albert Darque, Karine Baumstarck, Sylvie Bregigeon, Frédérique Retornaz,

Journal: Medicine (Baltimore). 2018 Feb;97(6):e9852.

 

As HIV-infected patients grow older, some accumulate multiple health problems earlier than the noninfected ones in particular frailty phenotypes. Patients with frailty phenotype are at higher risk of adverse outcomes (worsening mobility, disability, hospitalization, and death within ...

Last Updated: 31 Dec 1969

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24-month HIV-free survival among infants born to HIV-positive women enrolled in Option B+ program in Kigali, Rwanda: The Kabeho Study.
 

Author(s): Michelle M Gill, Heather J Hoffman, Dieudonne Ndatimana, Placidie Mugwaneza, Laura Guay, Gilles F Ndayisaba, Emily A Bobrow, Anita Asiimwe, Lynne M Mofenson

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9445.

 

Lifelong antiretroviral therapy (ART) provision to all pregnant HIV-positive women ("Option B+") has been recommended by the World Health Organization since 2013, but there remain limited data on the effects of Option B+ on long-term HIV-free survival in breastfeeding HIV-exposed ...

Last Updated: 31 Dec 1969

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Efficacy of eculizumab in an adult patient with HIV-associated hemolytic uremic syndrome: A case report.
 

Author(s): Marine Freist, Cyril Garrouste, Nora Szlavik, Paul Coppo, Alexandre Lautrette, Anne Elisabeth Heng

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9358.

 

Hemolytic uremic syndrome (HUS) in Human Immunodeficiency Virus (HIV)-positive patients has become a rare cause of kidney injury since the era of highly active antiretroviral therapy (HAART). Plasma exchange and antiretroviral therapy were previously recommended but often failed to ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "HIV" returned 4189 free, full-text review articles on human participants. First 3 results:

Concomitant systemic lupus erythematosus and HIV infection: A rare case report and literature review.
 

Author(s): Hong-Yan Liao, Chuan-Min Tao, Jun Su

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9337.

 

Coexisting systemic lupus erythematosus (SLE) and human immunodeficiency virus (HIV) infection cases are rare worldwide. Great challenges are posed on the diagnosis and treatment of such concurrent cases.

Last Updated: 31 Dec 1969

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Review of toxoplasmosis in Morocco: seroprevalence and risk factors for toxoplasma infection among pregnant women and HIV- infected patients.
 

Author(s): Majda Laboudi

Journal:

 

Toxoplasmosis is a disease caused by a protozoal parasite:. This infection can cause severe illness when the organism is contracted congenitally or when it is reactivated in immunosuppressed people. In this paper we review for the first time prevalence and risk factors ofamong pregnant ...

Last Updated: 31 Dec 1969

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Closing the gaps in the HIV care continuum.
 

Author(s): Ruanne V Barnabas, Connie Celum

Journal:

 

In a Perspective, Ruanne Barnabas and Connie Celum discuss the implications of the accompanying Link4Health and Engage4Health studies for HIV care in sub-Saharan Africa.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Immunogenicity of Clade C ALVAC and gp120 HIV Vaccine
 

Status: Recruiting

Condition Summary: HIV Infections

 

Last Updated: 13 Sep 2017

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Safety and Immune Response to a Clade C DNA HIV Vaccine
 

Status: Recruiting

Condition Summary: HIV Infections

 

Last Updated: 28 Dec 2016

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