Harlequin Syndrome

Common Name(s)

Harlequin Syndrome

Harlequin syndrome was first coined by Lance and Drummond in 1988 when they described five cases of unilateral (on one side) flushing and sweating. The asymmetrical facial sweating and flushing described with this condition has been named the 'Harlequin Sign'.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Harlequin Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Harlequin Syndrome" returned 19 free, full-text research articles on human participants. First 3 results:

Do you know this syndrome? Harlequin syndrome.
 

Author(s): Nelise Ritter Hans-Bittner, Guilherme Canho Bittner, G√ľnter Hans Filho

Journal: An Bras Dermatol. ;93(4):585-586.

 

Harlequin syndrome is a rare condition in which one half of the face fails to flush and sweat due to damage of the sympathetic fibers on the ipsilateral side. The majority of cases are idiopathic, but may be iatrogenic or caused by space-occupying lesions or brainstem infarction. ...

Last Updated: 31 Dec 1969

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Harlequin syndrome and Horner syndrome after neck schwannoma excision in a pediatric patient: A case report.
 

Author(s): Dong Hoon Lee, Jong Yuap Seong, Tae Mi Yoon, Joon Kyoo Lee, Sang Chul Lim

Journal: Medicine (Baltimore). 2017 Nov;96(45):e8548.

 

Harlequin syndrome is an extremely rare benign condition characterized by unilateral facial flushing and sweating.

Last Updated: 31 Dec 1969

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Unilateral facial and upper truncal anhidrosis and absence of physiological flushing: A case of idiopathic harlequin syndrome.
 

Author(s): Crystal Zhen Yu Phuan, Hong Liang Tey

Journal: Indian J Dermatol Venereol Leprol. ;83(6):740.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Harlequin Syndrome" returned 1 free, full-text review articles on human participants. First 3 results:

Harlequin syndrome in childhood--case report.
 

Author(s): Juliano de Avelar Breunig, Mariana Hartmann, Cristiano Firpo Freire, Hiram Larangeira de Almeida

Journal: An Bras Dermatol. ;87(6):907-9.

 

Harlequin syndrome happens in only one side of the face. In the affected half, the face does not sweat or flush even with simulation. Arms and trunk could also be affected. This condition is induced by heat, exercise and emotional factors. The article reports a case of a nine-year-old ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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