Heart Disease

Common Name(s)

Heart Disease

Heart disease, also known as cardiovascular disease, is a term that describes a range of conditions that affect the heart. Diseases that affect the heart’s muscle (cardiomyopathy), rhythm (arrhythmia), structure (congenital heart defect), or blood vessels (coronary artery disease) are all forms of heart disease. Symptoms of heart disease depend on the specific condition. A weak heart muscle may cause fatigue, dizziness, and swelling of the legs, ankles and feet. Symptoms of an abnormal heart rhythm may include chest pain, dizziness, shortness of breath, or a racing or slow heartbeat. Individuals who were born with an abnormality in the structure of the heart may experience swelling in the legs or abdomen, pale or blue skin color, or shortness of breath. Chest pain, shortness of breath, and pain in the legs, arms, neck, jaw, or throat may be a result of heart disease in the blood vessels.

There are many causes of heart disease, depending on the specific form. There are also a few factors that can increase the risk for heart problems. These factors include older age, poor diet, high blood pressure, smoking, a family history of heart disease, stress, obesity, diabetes, high cholesterol levels, and poor hygiene. Doctors use a combination of tests and exams to diagnose heart disease. These tests may include a medical history, a family history, a physical exam, blood tests, an assessment of heart rhythm using electrical signals (electrocardiogram or ECG), and an ultrasound image of your heart (echocardiogram). Lifestyle changes, such as exercising more, eating a healthy diet, or quitting smoking may decrease the risk for heart disease. Some forms of heart disease require treatment with medication, surgery or other medical procedures. Emergency medical attention is recommended for symptoms of chest pain, fatigue or fainting in association with heart disease. Talk with your doctor to decide which treatment option is best for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heart Disease" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Mended Hearts, Inc.

Our mission is dedicated to “Inspiring hope and improving the quality of life for heart patients and their families through ongoing peer-to-peer support”.

Last Updated: 11 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heart Disease" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Mended Hearts, Inc.

Our mission is dedicated to “Inspiring hope and improving the quality of life for heart patients and their families through ongoing peer-to-peer support”.

http://www.mendedhearts.org

Last Updated: 11 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Heart Disease" returned 8824 free, full-text research articles on human participants. First 3 results:

Influence of fixed-dose combination perindopril/amlodipine on target organ damage in patients with arterial hypertension with and without ischemic heart disease (results of EPHES trial).
 

Author(s): Ganna D Radchenko, Liliya O Mushtenko, Yuriy M Sirenko

Journal:

 

The EPHES trial (Evaluation of influence of fixed dose combination Perindo-pril/amlodipine on target organ damage in patients with arterial HypErtension with or without iSchemic heart disease) compared the dynamics of target organ damage (TOD) in hypertensive patients with and without ...

Last Updated: 31 Dec 1969

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Early severe coronary heart disease and ischemic heart failure in homozygous familial hypercholesterolemia: A case report.
 

Author(s): Hongyu Kuang, Xue Zhou, Li Li, Qijian Yi, Weinian Shou, Tiewei Lu

Journal: Medicine (Baltimore). 2018 Oct;97(42):e12869.

 

Familial hypercholesterolemia (FH) is a common inherited cause of coronary heart disease (CHD) and premature death in an early age. Nevertheless, an ischemic heart failure (IHF) associated with FH seems to be rare, and an early diagnosis and therapy could influence the prognosis.

Last Updated: 31 Dec 1969

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Identification of volume parameters monitored with a noninvasive ultrasonic cardiac output monitor for predicting fluid responsiveness in children after congenital heart disease surgery.
 

Author(s): Yu-Wei Cheng, Feng Xu, Jing Li

Journal: Medicine (Baltimore). 2018 Sep;97(39):e12289.

 

No previous study has used an ultrasonic cardiac output monitor (USCOM) to assess volume parameters, such as stroke volume variation (SVV), in order to predict the volume status and fluid responsivenes in children after congenital heart disease (CHD) surgery. The present prospective ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Heart Disease" returned 1339 free, full-text review articles on human participants. First 3 results:

Management of Heart Failure in Adult Congenital Heart Disease.
 

Author(s): Aarthi Sabanayagam, Omer Cavus, Jordan Williams, Elisa Bradley

Journal: Heart Fail Clin. 2018 Oct;14(4):569-577.

 

There are more than 1 million adults with congenital heart disease (ACHD) in the United States. Heart failure (HF) is the most common late cardiovascular complication. These patients are challenging to manage given their diverse presentation, anatomy, and complex hemodynamics. Examination ...

Last Updated: 31 Dec 1969

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ENPP1 K121Q (rs1044498 C > A) genetic polymorphism confers a high risk of susceptibility to coronary heart disease: A PRISMA-compliant article.
 

Author(s): Jia-Yin Di, Meng-Lu Dai, Zong-Xin Zhang

Journal: Medicine (Baltimore). 2018 Jul;97(27):e11236.

 

Previous studies suggested an association between K121Q (rs1044498 C > A) in ecto-nucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) gene and the risk of coronary heart disease (CHD), but the results have been inconsistent. In this study, we performed a meta-analysis of ...

Last Updated: 31 Dec 1969

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Association between the PON1 Q192R polymorphism and coronary heart disease in Chinese: A meta-analysis.
 

Author(s): Zhen Zhang, Junke Ou, Peiling Cai, Bei Niu, Jian Li

Journal: Medicine (Baltimore). 2018 Jun;97(26):e11151.

 

The relation has not been reported consistently between the PON1 Q192R polymorphism and coronary heart disease (CHD). To clarify the discrepancy, we performed the present meta-analysis to evaluate the association between the PON1 gene Q192R polymorphism and CHD risk in Chinese population.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Mar 2018

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Rheumatic Heart Disease School Project
 

Status: Recruiting

Condition Summary: Rheumatic Heart Disease

 

Last Updated: 8 Oct 2018

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The Application Value of STIC in the Diagnosis of Fetal Complex Congenital Heart Disease
 

Status: Recruiting

Condition Summary: Congenital Heart Disease

 

Last Updated: 24 Oct 2018

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