Heart Disease

Common Name(s)

Heart Disease

Heart disease, also known as cardiovascular disease, is a term that describes a range of conditions that affect the heart. Diseases that affect the heart’s muscle (cardiomyopathy), rhythm (arrhythmia), structure (congenital heart defect), or blood vessels (coronary artery disease) are all forms of heart disease. Symptoms of heart disease depend on the specific condition. A weak heart muscle may cause fatigue, dizziness, and swelling of the legs, ankles and feet. Symptoms of an abnormal heart rhythm may include chest pain, dizziness, shortness of breath, or a racing or slow heartbeat. Individuals who were born with an abnormality in the structure of the heart may experience swelling in the legs or abdomen, pale or blue skin color, or shortness of breath. Chest pain, shortness of breath, and pain in the legs, arms, neck, jaw, or throat may be a result of heart disease in the blood vessels.

There are many causes of heart disease, depending on the specific form. There are also a few factors that can increase the risk for heart problems. These factors include older age, poor diet, high blood pressure, smoking, a family history of heart disease, stress, obesity, diabetes, high cholesterol levels, and poor hygiene. Doctors use a combination of tests and exams to diagnose heart disease. These tests may include a medical history, a family history, a physical exam, blood tests, an assessment of heart rhythm using electrical signals (electrocardiogram or ECG), and an ultrasound image of your heart (echocardiogram). Lifestyle changes, such as exercising more, eating a healthy diet, or quitting smoking may decrease the risk for heart disease. Some forms of heart disease require treatment with medication, surgery or other medical procedures. Emergency medical attention is recommended for symptoms of chest pain, fatigue or fainting in association with heart disease. Talk with your doctor to decide which treatment option is best for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heart Disease" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Mended Hearts, Inc.

Our mission is dedicated to “Inspiring hope and improving the quality of life for heart patients and their families through ongoing peer-to-peer support”.

Last Updated: 11 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heart Disease" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Mended Hearts, Inc.

Our mission is dedicated to “Inspiring hope and improving the quality of life for heart patients and their families through ongoing peer-to-peer support”.

http://www.mendedhearts.org

Last Updated: 11 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Heart Disease" returned 9715 free, full-text research articles on human participants. First 3 results:

Intravenous anesthesia with nitroglycerin inhalation for surgical abortion in a patient with severe congenital heart disease and low oxygen saturation: A case report.
 

Author(s): Zhengfeng Gu, Lian Xin, Zhiping Wang, Jun Wang

Journal: Medicine (Baltimore). 2018 Jun;97(25):e11108.

 

Congenital heart disease and pulmonary arterial hypertension are perilous to a gravida for the high morbidity and mortality.

Last Updated: 31 Dec 1969

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PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance.
 

Author(s): Jake Jianjun Wen, Yuhui Whitney Yin, Nisha Jain Garg

Journal:

 

Chagasic cardiomyopathy is caused by Trypanosoma cruzi infection. Poly(ADP-ribose) polymerase 1 (PARP1) is known for its function in nuclear DNA repair. In this study, we have employed genetic deletion and chemical inhibition approaches to determine the role of PARP1 in maintaining ...

Last Updated: 31 Dec 1969

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Rheumatic heart disease in pregnancy: a report of 2 cases.
 

Author(s): Asaph Ziruma, Munyaradzi Innocent Nyakanda, Annie Fungai Muyotcha, Fungisai Nyarai Hove, Mugove Gerald Madziyire

Journal:

 

Pregnant women with severe mitral stenosis tend to experience clinical decompensation with approximately 50% mortality and they may experience adverse effects of the medication they are taking, notably congenital malformations from warfarin exposure. Corrective heart surgery may increase ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Heart Disease" returned 1460 free, full-text review articles on human participants. First 3 results:

Association between the PON1 Q192R polymorphism and coronary heart disease in Chinese: A meta-analysis.
 

Author(s): Zhen Zhang, Junke Ou, Peiling Cai, Bei Niu, Jian Li

Journal: Medicine (Baltimore). 2018 Jun;97(26):e11151.

 

The relation has not been reported consistently between the PON1 Q192R polymorphism and coronary heart disease (CHD). To clarify the discrepancy, we performed the present meta-analysis to evaluate the association between the PON1 gene Q192R polymorphism and CHD risk in Chinese population.

Last Updated: 31 Dec 1969

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Effect of various Danshen injections on patients with coronary heart disease after percutaneous coronary intervention: A protocol for a systematic review and network meta-analysis.
 

Author(s): Zehao Zhu, Yuanping Wang, Weilin Liao, Huimin Li, Dawei Wang

Journal: Medicine (Baltimore). 2018 Jun;97(24):e11062.

 

Patients with coronary heart disease (CHD) who undergo percutaneous coronary intervention (PCI) have a certain risk of vascular complications, including coronary restenosis and thrombosis. Many recent randomized controlled trials have reported that Danshen injection (DSI) combined ...

Last Updated: 31 Dec 1969

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The efficiency of endothelin receptor antagonist bosentan for pulmonary arterial hypertension associated with congenital heart disease: A systematic review and meta-analysis.
 

Author(s): Hong-Yu Kuang, Yu-Hao Wu, Qi-Jian Yi, Jie Tian, Chun Wu, We Nian Shou, Tie-Wei Lu

Journal: Medicine (Baltimore). 2018 Mar;97(10):e0075.

 

Oral bosentan has been widely applied in pulmonary arterial hypertension associated with congenital heart disease (PAH-CHD). A systemic review and meta-analysis was conducted for a therapeutic evaluation of oral bosentan in both adult and pediatric patients with PAH-CHD. The acute ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Mar 2018

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Rheumatic Heart Disease School Project
 

Status: Recruiting

Condition Summary: Rheumatic Heart Disease

 

Last Updated: 20 Sep 2017

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Patient NAVIgation to Reduce Readmissions Among Black Men With Heart Disease
 

Status: Recruiting

Condition Summary: Heart Diseases

 

Last Updated: 31 Aug 2017

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