Hepatitis B

Common Name(s)

Hepatitis B

Hepatitis B is a viral hepatitis that affects the liver and is caused by the hepatitis B virus, or HBV. The liver is an organ found on the right side of our belly (abdomen) under the rib cage. It cleans our blood of toxins, poisons, and bacteria. It produces bile which helps our body breakdown food. Hepatitis B occurs when HBV causes a person’s immune system to attack the liver. Symptoms may be mild to severe and may include nausea, diarrhea, fatigue, and jaundice (yellowing of the skin). Usually the body is able to fight the infection within 6 months (acute infection). Chronic HBV infections may lead to liver cancer, permanent scarring of the liver (cirrhosis), or liver failure. It is rare for HBV to become chronic in adults, but 80% of infected newborns and 20% of infected children under 5 develop a chronic infection. HBV is spread from person to person through blood, semen or other body fluids. The most common ways to get infected by HBV are through sexual contact with someone who has HBV, sharing of infected needles (usually during IV drug use), accidental needle sticks to health care workers working with patients who have HBV, and mother to child during childbirth if the mother has HBV.

A vaccine is available to prevent HBV infection. The vaccine may even be given to newborns exposed to HBV during childbirth to successfully prevent infection. It is important to call your physician within 12 hours if you know you have been exposed to HBV and are not vaccinated. There are treatments available to decrease your chance of becoming infected. If the condition becomes chronic, there are medications available to help slow the damage to the liver but there is no cure at this time. HBV infections are diagnosed through blood tests and possibly liver biopsies. Talk with your doctor if you or a family member has been diagnosed with hepatitis B. Support groups are also good resources of support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis B" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

Last Updated: 11 Jul 2016

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis B" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

http://www.thestdproject.com/

Last Updated: 11 Jul 2016

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis B" returned 8978 free, full-text research articles on human participants. First 3 results:

Epidemiological study of hepatitis B and hepatitis C infections in Northeastern China and the beneficial effect of the vaccination strategy for hepatitis B: a cross-sectional study.
 

Author(s): Shishen Wang, Yuhui Tao, Yuchun Tao, Jing Jiang, Li Yan, Chong Wang, Yaxuan Ding, Jianxing Yu, Dinghui Zhao, Xiumei Chi, Xiaomei Wang, Ruihong Wu, Xiuzhu Gao, Ying Shi, Yazhe Guan, Yingchun Li, Yanli Xing, Haiyan Sun, Changhua Ta, Chao Wang, Junqi Niu, Jing Meng, Hongqin Xu

Journal:

 

Viral hepatitis, mainly hepatitis B and C, is a serious public health problem worldwide. In China, the prevalence of hepatitis B virus (HBV) infection remains high, while that of hepatitis C virus (HCV) infection is controversial. This study investigated the epidemiology of HBV and ...

Last Updated: 31 Dec 1969

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The association between PIN1 genetic polymorphisms and the risk of chronic hepatitis B and hepatitis B virus-related liver cirrhosis: A case-control study.
 

Author(s): Li Huang, Zhuning Mo, Shan Li, Xue Qin

Journal: Medicine (Baltimore). 2018 Aug;97(35):e12123.

 

Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 (PIN1) reportedly plays a crucial role in tissue inflammation and tumourigenesis. Our previous studies have demonstrated that PIN1 gene polymorphisms are significantly related to the pathogenesis of hepatitis B virus (HBV)-related ...

Last Updated: 31 Dec 1969

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High level of serum Cripto-1 in hepatocellular carcinoma, especially with hepatitis B virus infection.
 

Author(s): Yingyu Zhang, Hongqin Xu, Xiumei Chi, Yuxiang Fan, Ying Shi, Junqi Niu

Journal: Medicine (Baltimore). 2018 Aug;97(35):e11781.

 

Human Cripto-1 (CR-1), a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic protein family (EGF-CFC), is highly expressed in a variety of human cancers. We aimed to detect serum CR-1 level in liver diseases especially in hepatocellular carcinoma (HCC) patients.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis B" returned 918 free, full-text review articles on human participants. First 3 results:

Statins on hepatocellular carcinoma risk in hepatitis B or C patients protocol for a systematic review and meta-analysis.
 

Author(s): Zhiguo Li, Ying Li, Xiaoke Li, Ludan Zhang, Nanqi Zhao, Hongbo Du, Bo Zhou, Yong'an Ye

Journal: Medicine (Baltimore). 2018 Aug;97(34):e11950.

 

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. Chronic hepatitis B (HBV) and C virus (HCV) infection causes liver cancer. This protocol is to provide the methods used to assess the relationship between statins and HCC risk in hepatitis B or C patients.

Last Updated: 31 Dec 1969

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Dermatomyositis as an extrahepatic manifestation of hepatitis B virus-related hepatocellular carcinoma: A case report and literature review.
 

Author(s): Juqiang Han, Shuai Wang, Thomas Ngai Yeung Kwong, Jian Liu

Journal: Medicine (Baltimore). 2018 Aug;97(33):e11586.

 

Dermatomyositis is an idiopathic inflammatory myopathy with specific cutaneous manifestations, which is closely associated with malignancy. However, the exact mechanism remains elusive. Even less is known about dermatomyositis with hepatocellular carcinoma (HCC).

Last Updated: 31 Dec 1969

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Is Hepatitis B Virus a Player in Pancreatic Cancer?
 

Author(s): Traian Dumitrascu, Pascal Pineau

Journal: Chirurgia (Bucur). ;113(3):344-352.

 

Pancreatic cancer (i.e., pancreatic ductal adenocarcinoma, PDAC) is an important healthcare issue and a highly lethal disease. Thus, almost 80% of patients with PDAC will die within one year after diagnosis. Several factors including smoking, obesity, advanced age, diabetes mellitus ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 8 Aug 2018

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Hepatitis B Vaccine for Non-responders
 

Status: Recruiting

Condition Summary: Hepatitis B

 

Last Updated: 9 Apr 2018

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Hepatitis B Prevalence in the Turkish Population Living in Middle Limburg
 

Status: Recruiting

Condition Summary: Hepatitis B

 

Last Updated: 9 Jan 2018

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