Hepatitis D

Common Name(s)

Hepatitis D

Hepatitis D is a viral hepatitis that affects the liver and is caused by the hepatitis D virus, or HDV. HDV can only infect people who have hepatitis B, but it is important to remember that not all people with hepatitis B will know they have the condition because they may not have symptoms. An infection with HDV makes the symptoms of hepatitis B worse and increases liver damage. Symptoms may include sudden fever, extreme tiredness, nausea, lack of appetite, stomach pain, and jaundice (yellowing of the skin). HDV does not always cause symptoms. Most people infected with HDV recover within a month. About 10% of people infected with HDV develop a chronic infection. Chronic HDV infection may cause chronic active hepatitis leading to permanent liver scarring (cirrhosis) and liver failure. HDV is spread through contact with infected blood. Common ways of to become infected with HDV include sharing of infected needles, having sexual contact with a person infected by HDV, and from mother to child during childbirth if the mother is infected with HDV. Hepatitis D is diagnosed through blood tests and possibly a liver biopsy.

A vaccine is available to prevent HBV infection which there also will prevent HDV infection. If the condition becomes chronic, there are treatments available to help slow the damage to the liver but there is no cure at this time. HDV infections are diagnosed through blood tests and possibly liver biopsies. Talk with your doctor if you or a family member has been diagnosed with hepatitis D. Support groups are also good resources of support and information. See also Hepatitis B.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis D" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis D" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis D" returned 196 free, full-text research articles on human participants. First 3 results:

Atypical crusted scabies in a patient with chronic liver disease caused by hepatitis B and D viruses.
 

Author(s): Mônica Santos, Gustavo Ávila Maquiné, Carolina Talhari, Antonio Pedro Mendes Schettini

Journal: An Bras Dermatol. 2018 Mar;93(2):277-278.

 

Crusted scabies is a less common variant of scabies that is highly contagious, difficult to treat and involves infestation by Sarcoptes scabiei var. hominis. The classical clinical presentation includes crusted, scaly and generally non-pruritic lesions usually located on the head, ...

Last Updated: 31 Dec 1969

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Hepatitis B and hepatitis D virus infections in the Central African Republic, twenty-five years after a fulminant hepatitis outbreak, indicate continuing spread in asymptomatic young adults.
 

Author(s): Narcisse Patrice Komas, Sumantra Ghosh, Mariama Abdou-Chekaraou, Pierre Pradat, Nasser Al Hawajri, Alexandre Manirakiza, Gina Laure Laghoe, Claudine Bekondi, Ségolène Brichler, Jean-Omer Ouavéné, Abdoulaye Sépou, Brice Martial Yambiyo, Jean Chrysostome Gody, Valentin Fikouma, Athénais Gerber, Natali Abeywickrama Samarakoon, Dulce Alfaiate, Caroline Scholtès, Nora Martel, Frédéric Le Gal, Hugo Lo Pinto, Ikram Amri, Olivier Hantz, David Durantel, Jean-Louis Lesbordes, Emmanuel Gordien, Philippe Merle, Tudor Drugan, Christian Trépo, Fabien Zoulim, Jean-Claude Cortay, Alan Campbell Kay, Paul Dény

Journal:

 

Hepatitis delta virus (HDV) increases morbidity in Hepatitis B virus (HBV)-infected patients. In the mid-eighties, an outbreak of HDV fulminant hepatitis (FH) in the Central African Republic (CAR) killed 88% of patients hospitalized in Bangui. We evaluated infections with HBV and ...

Last Updated: 31 Dec 1969

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Autophagy, apoptosis, vitamin D, and vitamin D receptor in hepatocellular carcinoma associated with hepatitis C virus.
 

Author(s): Mohamed Ahmed Abdel-Mohsen, Ahlam Abd-Allah El-Braky, Abeer Abd El-Rahim Ghazal, Mohammed Mohammed Shamseya

Journal: Medicine (Baltimore). 2018 Mar;97(12):e0172.

 

The aims of this study were to investigate the interplay between autophagy and apoptosis and to investigate the association between both of autophagy and apoptosis and vitamin D and its receptor in hepatitis C virus (HCV) viral infection and its implication in the progression into ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis D" returned 23 free, full-text review articles on human participants. First 3 results:

Vitamin D deficiency and hepatitis viruses-associated liver diseases: A literature review.
 

Author(s): Nghiem Xuan Hoan, Hoang Van Tong, Le Huu Song, Christian G Meyer, Thirumalaisamy P Velavan

Journal: World J. Gastroenterol.. 2018 Jan;24(4):445-460.

 

The secosteroid hormone vitamin D has, in addition to its effects in bone metabolism also functions in the modulation of immune responses against infectious agents and in inhibiting tumorigenesis. Thus, deficiency of vitamin D is associated with several malignancies, but also with ...

Last Updated: 31 Dec 1969

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Prevalence of hepatitis D virus infection in sub-Saharan Africa: a systematic review and meta-analysis.
 

Author(s): Alexander J Stockdale, Mas Chaponda, Apostolos Beloukas, Richard Odame Phillips, Philippa C Matthews, Athanasios Papadimitropoulos, Simon King, Laura Bonnett, Anna Maria Geretti

Journal: Lancet Glob Health. 2017 10;5(10):e992-e1003.

 

Hepatitis D virus (also known as hepatitis delta virus) can establish a persistent infection in people with chronic hepatitis B, leading to accelerated progression of liver disease. In sub-Saharan Africa, where HBsAg prevalence is higher than 8%, hepatitis D virus might represent ...

Last Updated: 31 Dec 1969

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Hepatitis D virus infection in Slovenian patients with chronic hepatitis B virus infection: a national prevalence study and literature review.
 

Author(s): Mateja M Jelen, Lea Hošnjak, Špela Štunf, Anja Zagožen, Kristina Fujs Komloš, Petra Markočič, Mario Poljak, Katja Seme

Journal: Acta Dermatovenerol Alp Pannonica Adriat. 2016 Sep;25(3):49-53.

 

Of the 350 million individuals chronically infected with hepatitis B virus (HBV) worldwide, approximately 15 to 20 million have been exposed to hepatitis D virus (HDV). This study determined for the first time the HDV prevalence in Slovenian patients with chronic HBV infection. In ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Ezetimibe for Patients With Chronic Hepatitis D
 

Status: Recruiting

Condition Summary: Chronic Hepatitis D

 

Last Updated: 28 Mar 2017

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The Hepatitis Delta International Network
 

Status: Recruiting

Condition Summary: Hepatitis D

 

Last Updated: 25 Aug 2017

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Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda Interferon
 

Status: Recruiting

Condition Summary: Liver Disease; Hepatitis D

 

Last Updated: 18 Sep 2018

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