Hepatitis E

Common Name(s)

Hepatitis E

Hepatitis E is a viral hepatitis that affects the liver and is caused by the hepatitis E virus, or HEV. The liver is an organ found on the right side of our belly (abdomen) under the rib cage. It cleans our blood of toxins, poisons, and bacteria. It produces bile which helps our body breakdown food. It stores vitamins, minerals and sugars. And it helps control cholesterol levels. Hepatitis E occurs when the hepatitis E virus causes the liver to swell, scar, and become inflamed, which stops it from working properly or completely Symptoms may include nausea, diarrhea, fatigue, and jaundice (yellowing of the skin). Hepatitis E symptoms usually go away after 4-6 weeks. It is rare for HEV to become chronic, but it can be very serious for pregnant women. HEV is spread through food or water that is contaminated with the feces (bowel movement) of people infected with HEV. There is some concern that it may also be passed through pigs in areas where HEV is common. There is no evidence that HEV is passed through sexual intercourse. It is very rarely passed from person to person. HEV is rare in developed nations. However, people who travel to the developing countries where HEV is common may be at risk. Outbreaks of hepatitis E have been reported in Central and South-East Asia, North and West Africa, and in Mexico, especially where fecal contamination of drinking water occurs. Physicians can diagnose hepatitis E through blood tests and stool tests that detect the presence of HEV. Physicians and hospitals can provide supportive care for individuals affected by HEV until they recover if needed. If HEV does become chronic, medications are available to help treat the condition. Talk with your doctor if you or a family member has been diagnosed with hepatitis to decide on the best treatment plan. Support groups are also good resources of support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis E" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis E" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis E" returned 933 free, full-text research articles on human participants. First 3 results:

Seroprevalence of hepatitis E virus in chronic hepatitis C in Brazil.
 

Author(s): Guilherme Bricks, Jorge Figueiredo Senise, Henrique Pott Junior, Giuliano Grandi, Amanda Passarini, Débora Bellini Caldeira, Dimas Carnaúba Junior, Hamilton Antonio Bonilha de Moraes, Celso Franscisco Hernandes Granato, Adauto Castelo

Journal: Braz J Infect Dis. ;22(2):85-91.

 

Hepatitis E virus infection in patients with underlying chronic liver disease is associated with liver decompensation and increased lethality. The seroprevalence of hepatitis E virus in patients with chronic hepatitis C in Brazil is unknown. This study aims to estimate the seroprevalence ...

Last Updated: 31 Dec 1969

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Hepatitis B virus genotypes A1, A2 and E in Cape Verde: Unequal distribution through the islands and association with human flows.
 

Author(s): Isabel Inês M de Pina-Araujo, Natalia Spitz, Caroline C Soares, Christian Niel, Barbara V Lago, Selma A Gomes

Journal:

 

Hepatitis B virus (HBV) diversity has not been previously studied in Cape Verde. The archipelago was discovered in 1460 by Portuguese explorers, who brought African slaves to colonise the islands. In this study, we investigated the HBV characteristics from 183 HBsAg-positive Cape ...

Last Updated: 31 Dec 1969

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Comparison of hepatitis E virus seroprevalence between HBsAg-positive population and healthy controls in Shandong province, China.
 

Author(s): Li Zhang, Zechun Jiang, Jingjing Lv, Jiaye Liu, Bingyu Yan, Yi Feng, Li Li, Guomin Zhang, Fuzhen Wang, Aiqiang Xu

Journal:

 

Persons with chronic hepatitis B (CHB) infection were reported to suffer severe disease after hepatitis E virus (HEV) superinfection, but the studies regarding HEV seroprevalence in this population were limited. A recent study in Vietnam found higher HEV seroprevalence among CHB patients ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis E" returned 75 free, full-text review articles on human participants. First 3 results:

Guillain-Barre syndrome caused by hepatitis E infection: case report and literature review.
 

Author(s): Xiaoqin Zheng, Liang Yu, Qiaomai Xu, Silan Gu, Lingling Tang

Journal:

 

Hepatitis E infection is a global disorder that causes substantial morbidity. Numerous neurologic illnesses, including Guillain-Barre syndrome (GBS), have occurred in patients with hepatitis E virus (HEV) infection.

Last Updated: 31 Dec 1969

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Recent knowledge on hepatitis E virus in Suidae reservoirs and transmission routes to human.
 

Author(s): Nicole Pavio, Virginie Doceul, Eugénie Bagdassarian, Reimar Johne

Journal:

 

Hepatitis E virus (HEV) causes self-limiting acute hepatitis in humans that can eventually result in acute liver failures or progress to chronic infections. While in tropical and sub-tropical areas, HEV infections are associated with important waterborne epidemics, in Northern countries, ...

Last Updated: 31 Dec 1969

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Host Innate Immunity against Hepatitis E Virus and Viral Evasion Mechanisms.
 

Author(s): Sangmin Kang, Jinjong Myoung

Journal: J. Microbiol. Biotechnol.. 2017 Oct;27(10):1727-1735.

 

Hepatitis E virus (HEV) infections cause epidemic or sporadic acute hepatitis, which are mostly self-limiting. However, viral infection in immunocompromised patients and pregnant women may result in serious consequences, such as chronic hepatitis and liver damage, mortality of the ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Seroprevalence of Hepatitis E in People With an Organ Transplant
 

Status: Recruiting

Condition Summary: Hepatitis E

 

Last Updated: 13 Feb 2018

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Effectiveness Trial to Evaluate Protection of Pregnant Women by Hepatitis E Vaccine in Bangladesh.
 

Status: Recruiting

Condition Summary: Hepatitis E Infection

 

Last Updated: 23 Apr 2018

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HepNet Pilot Trial: Multicenter Trial for the Treatment of Chronic Hepatitis E With Sofosbuvir (SofE)
 

Status: Recruiting

Condition Summary: Hepatitis E; Hepatitis Chronic Viral

 

Last Updated: 15 Feb 2018

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