Hepatitis

Common Name(s)

Hepatitis

Hepatitis is a medical condition that affects the liver. The liver is an organ found in the right side of our belly (abdomen) under the rib cage. The liver cleans our blood of toxins, poisons, and bacteria; produces bile that helps our body breakdown food; stores vitamins, minerals and sugars; and helps control cholesterol levels. Hepatitis occurs when the liver swells, scars, and becomes inflamed, which stops it from working properly or completely.

Symptoms of hepatitis may include jaundice (yellowing of the skin), poor appetite, abdominal pain, enlargement of the abdomen, and a general feeling of being unwell, or malaise. Sometimes hepatitis can heal on its own, but other times it will progress to fibrosis and cirrhosis (types of scarring).

The most common causes of hepatitis are viral infections, but other medical conditions, including autoimmune disorders, certain medications and toxic substances, including alcohol and drugs, can also cause hepatitis. Viral hepatitis includes Hepatitis A, B, C, D and E. There are vaccines available to help prevent types A and B. Hepatitis A and E usually resolve on their own, whereas hepatitis B, C, and D can be chronic and serious. Transmission is dependent on the virus type. Physicians diagnose hepatitis by assessing symptoms during a physical exam, blood tests, and, if needed, using a liver biopsy.

Treatment for hepatitis is usually supportive, preventing further damage by avoiding toxic medications (including acetaminophen or Tylenol), drugs or alcohol, and, if possible, reversing the underlying cause. There are medications available to treat chronic hepatitis and, due to medical research, treatments are improving rapidly. Talk with your doctor if you or a family member has been diagnosed with hepatitis to decide on the best treatment plan.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

Last Updated: 11 Jul 2016

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

http://www.thestdproject.com/

Last Updated: 11 Jul 2016

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis" returned 24156 free, full-text research articles on human participants. First 3 results:

Macrocytic anemia is associated with the severity of liver impairment in patients with hepatitis B virus-related decompensated cirrhosis: a retrospective cross-sectional study.
 

Author(s): Jian Yang, Bin Yan, Lihong Yang, Huimin Li, Yajuan Fan, Feng Zhu, Jie Zheng, Xiancang Ma

Journal:

 

Macrocytic anemia is common in liver disease. However, its role in hepatitis B virus (HBV)-related decompensated cirrhosis remains unknown. The aim of the present study was to determine the association between macrocytic anemia and the severity of liver impairment in patients with ...

Last Updated: 31 Dec 1969

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Update: Recommendations of the Advisory Committee on Immunization Practices for Use of Hepatitis A Vaccine for Postexposure Prophylaxis and for Preexposure Prophylaxis for International Travel.
 

Author(s): Noele P Nelson, Ruth Link-Gelles, Megan G Hofmeister, José R Romero, Kelly L Moore, John W Ward, Sarah F Schillie

Journal:

 

Postexposure prophylaxis (PEP) with hepatitis A (HepA) vaccine or immune globulin (IG) effectively prevents infection with hepatitis A virus (HAV) when administered within 2 weeks of exposure. Preexposure prophylaxis against HAV infection through the administration of HepA vaccine ...

Last Updated: 31 Dec 1969

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Hepatitis A Virus Outbreaks Associated with Drug Use and Homelessness - California, Kentucky, Michigan, and Utah, 2017.
 

Author(s): Monique Foster, Sumathi Ramachandran, Katie Myatt, Danielle Donovan, Susan Bohm, Jay Fiedler, Bree Barbeau, Jim Collins, Douglas Thoroughman, Eric McDonald, Jonathan Ballard, Jeffrey Eason, Cynthia Jorgensen

Journal:

 

During 2017, CDC received 1,521 reports of acute hepatitis A virus (HAV) infections from California, Kentucky, Michigan, and Utah; the majority of infections were among persons reporting injection or noninjection drug use or homelessness. Investigations conducted by local and state ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis" returned 2787 free, full-text review articles on human participants. First 3 results:

Statins on hepatocellular carcinoma risk in hepatitis B or C patients protocol for a systematic review and meta-analysis.
 

Author(s): Zhiguo Li, Ying Li, Xiaoke Li, Ludan Zhang, Nanqi Zhao, Hongbo Du, Bo Zhou, Yong'an Ye

Journal: Medicine (Baltimore). 2018 Aug;97(34):e11950.

 

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. Chronic hepatitis B (HBV) and C virus (HCV) infection causes liver cancer. This protocol is to provide the methods used to assess the relationship between statins and HCC risk in hepatitis B or C patients.

Last Updated: 31 Dec 1969

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Hepatitis B virus infection: Defective surface antigen expression and pathogenesis.
 

Author(s): Chun-Chen Wu, Ying-Shan Chen, Liang Cao, Xin-Wen Chen, Meng-Ji Lu

Journal: World J. Gastroenterol.. 2018 Aug;24(31):3488-3499.

 

Hepatitis B virus (HBV) infection is a global public health concern. HBV causes chronic infection in patients and can lead to liver cirrhosis, hepatocellular carcinoma, and other severe liver diseases. Thus, understanding HBV-related pathogenesis is of particular importance for prevention ...

Last Updated: 31 Dec 1969

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Form confers function: Case of the 3'X region of the hepatitis C virus genome.
 

Author(s): Mariola Dutkiewicz, Jerzy Ciesiołka

Journal: World J. Gastroenterol.. 2018 Aug;24(30):3374-3383.

 

At the 3' end of genomic hepatitis C virus (HCV) RNA there is a highly conserved untranslated region, the 3'X-tail, which forms part of the 3'UTR. This region plays key functions in regulation of critical processes of the viral life cycle. The 3'X region is essential for viral replication ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Hepatitis Delta International Network
 

Status: Recruiting

Condition Summary: Hepatitis D

 

Last Updated: 25 Aug 2017

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Hepatitis C Positive Donor Into Hepatitis C Negative Recipients
 

Status: Not yet recruiting

Condition Summary: Hepatitis C

 

Last Updated: 31 Oct 2018

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Immune Cell Dysfunction in Severe Alcoholic Hepatitis
 

Status: Recruiting

Condition Summary: Hepatitis

 

Last Updated: 30 Jan 2018

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