Herpetic keratitis

Common Name(s)

Herpetic keratitis, Herpes zoster ophthalmicus

Herpetic keratitis is a herpes simplex virus infection of the eye. There are two types of herpes viruses, herpes simplex 1 (HS1) and 2 (HS2). HS2 herpetic keratitis is more rare since HS2 is sexually transmitted. HS1, however can spread to the eye by touching an infected mouth sore and then touching the eye. Symptoms of herpetic keratitis include redness, photophobia (light sensitivity), blurred vision, tearing, and pain. Herpetic keratitis is also the most common form of infectious blindness in the world. Most infections, however, are healed on their own within three weeks. Oral and topical antiviral therapies are also effective treatments for herpetic keratitis.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Herpetic keratitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Herpetic keratitis" returned 48 free, full-text research articles on human participants. First 3 results:

Self-Retained Amniotic Membrane Combined With Antiviral Therapy for Herpetic Epithelial Keratitis.
 

Author(s): Anny M S Cheng, Scheffer C G Tseng

Journal: Cornea. 2017 Nov;36(11):1383-1386.

 

To evaluate the therapeutic benefit of self-retained cryopreserved amniotic membrane in conjunction with oral antiviral therapy in herpetic epithelial keratitis.

Last Updated: 31 Dec 1969

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CXCL9 compensates for the absence of CXCL10 during recurrent Herpetic stromal keratitis.
 

Author(s): Deena Tajfirouz, Devin M West, Xiao-Tang Yin, Chloe A Potter, Robyn Klein, Patrick M Stuart

Journal: Virology. 2017 06;506():7-13.

 

Herpetic stromal keratitis (HSK) is a disease that is typically associated with reactivation of a latent HSV-1 infection. This disease is driven, in part, by chemokines that recruit leukocytes to the cornea. Surprisingly, neutralization of CXCL10 significantly reduced disease, while ...

Last Updated: 31 Dec 1969

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Clinical evaluation of deep anterior lamellar keratoplasty using glycerol-cryopreserved corneal tissues for refractory herpetic stromal keratitis: An observational study.
 

Author(s): Xin Liu, Qi Zhou, Xinyu Huang, Zhenxing Liu, Yanlong Bi

Journal: Medicine (Baltimore). 2016 Sep;95(39):e4892.

 

The study aimed to evaluate the therapeutic effects of deep anterior lamellar keratoplasty (DALK) using glycerol-cryopreserved corneal tissues (GCCTs) in patients with refractive herpes simplex keratitis (HSK). This article was a retrospective, noncomparative, and interventional case ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Herpetic keratitis" returned 5 free, full-text review articles on human participants. First 3 results:

A systematic review and meta-analysis to compare the efficacy of acyclovir 3% ophthalmic ointment to idoxuridine in curing herpetic keratitis by Day 7 of treatment.
 

Author(s): Diane E Balderson, Gengqian Cai, Michael A Fries, David M Kleinman, Megan M McLaughlin, Trupti M Trivedi, John I Wurzelmann, Sheila B Young

Journal:

 

This objective of the review and analysis is to demonstrate that acyclovir (ACV) 3% ophthalmic ointment is superior to idoxuridine (IDU) in treating herpetic keratitis (HK) presenting as dendritic and geographic ulcer sub-types.

Last Updated: 31 Dec 1969

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Corneal lymphangiogenesis in herpetic stromal keratitis.
 

Author(s): Paul J Park, Michael Chang, Nitin Garg, Jimmy Zhu, Jin-Hong Chang, Deepak Shukla

Journal: Surv Ophthalmol. ;60(1):60-71.

 

Corneal lymphangiogenesis is the extension of lymphatic vessels into the normally alymphatic cornea, a process that compromises the cornea's immune-privileged state and facilitates herpetic stromal keratitis (HSK). HSK results most commonly from infection by herpes simplex virus-1 ...

Last Updated: 31 Dec 1969

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Potential function of miRNAs in herpetic stromal keratitis.
 

Author(s): Sachin Mulik, Siddheshvar Bhela, Barry T Rouse

Journal:

 

MicroRNAs (miRNAs), the newly discovered regulators of gene expression, act by promoting degradation of mRNA and/or by inhibiting protein expression. Dysregulation of miRNA expression has been noted in an expanding number of diseases; and in some instances, manipulating miRNA expression ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Femtosecond Laser-assisted Corneal Debridement for Herpes Simplex Keratitis
 

Status: Recruiting

Condition Summary: Herpes Simplex Keratitis

 

Last Updated: 21 Feb 2018

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Observation on the Herpes Simplex Keratitis
 

Status: Recruiting

Condition Summary: Keratitis, Herpetic

 

Last Updated: 5 Jan 2017

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