Herpes simiae B virus is mostly found in macaque monkeys. The virus may be transmitted to humans through a bite or scratch wound. When humans become infected with the B virus, the infection will cause severe neurological damage or death. In order to prevent death, treatment must be administered extremely quickly in response to the infection. The wound must be cleaned and washed thoroughly for a minimum of fifteen full minutes. After identifying the suspected animal or exposure to materials exposed to infected macaques, the thoroughness of wound cleansing, and the type of wound, antiviral treatment may be available. These criteria must be considered to identify the probability of infection by the herpes simiae B virus.