Histoplasmosis

Common Name(s)

Histoplasmosis

Histoplasmosis is an infection caused by breathing in spores of a fungus found in bird and bat droppings. Most people never develop symptoms and aren’t aware they are infected. The exceptions are infants and those with compromised immune systems. Effective treatments are available for even the most severe forms of histoplasmosis. If symptoms appear, they usually do so 3 to 17 days after exposure and may include fever, chills, headache, muscle aches, dry cough, chest discomfort, joint pain and a rash. In more severe cases, treatment plans with one or more antifungal drugs are prescribed.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Histoplasmosis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Histoplasmosis" returned 371 free, full-text research articles on human participants. First 3 results:

Clinical outcomes and risk factors for death from disseminated histoplasmosis in patients with AIDS who visited a high-complexity hospital in Campo Grande, MS, Brazil.
 

Author(s): Barbara Cristina Scarcelli Boigues, Anamaria Mello Miranda Paniago, Gláucia Moreira Espíndola Lima, Maina de Oliveira Nunes, Silvia Naomi de Oliveira Uehara

Journal: Rev. Soc. Bras. Med. Trop.. ;51(2):155-161.

 

Disseminated histoplasmosis (DH) is a systemic mycosis caused by Histoplasma capsulatum (H. capsulatum) and is characterized by progressive and fatal evolution in immunocompromised patients. Moreover, it is considered an AIDS-defining disease.

Last Updated: 31 Dec 1969

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Central nervous system histoplasmosis: Multicenter retrospective study on clinical features, diagnostic approach and outcome of treatment.
 

Author(s): Joseph Wheat, Thein Myint, Ying Guo, Phebe Kemmer, Chadi Hage, Colin Terry, Marwan M Azar, James Riddell, Peter Ender, Sharon Chen, Kareem Shehab, Kerry Cleveland, Eden Esguerra, James Johnson, Patty Wright, Vanja Douglas, Pascalis Vergidis, Winnie Ooi, John Baddley, David Bamberger, Raed Khairy, Holenarasipur R Vikram, Elizabeth Jenny-Avital, Geetha Sivasubramanian, Karen Bowlware, Barbara Pahud, Juan Sarria, Townson Tsai, Maha Assi, Satish Mocherla, Vidhya Prakash, David Allen, Catherine Passaretti, Shirish Huprikar, Albert Anderson

Journal: Medicine (Baltimore). 2018 03;97(13):e0245.

 

Central nervous system (CNS) involvement occurs in 5 to 10% of individuals with disseminated histoplasmosis. Most experience has been derived from small single center case series, or case report literature reviews. Therefore, a larger study of central nervous system (CNS) histoplasmosis ...

Last Updated: 31 Dec 1969

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[Skin lesions of a disseminated histoplasmosis in Peru].
 

Author(s): W Samir Cubas, Gerardo Jiménez, Juan Vega

Journal: Rev Chilena Infectol. 2017 Dec;34(6):613-614.

 

The dermatological manifestations of disseminated histoplasmosis present in about 17% of the cases, is a challenge for its diagnosis. We report the case of a patient from the northern coast of Peru, who presented diffuse dermal lesions, erythema-violaceous nodules, and ulcers histopathologically ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Histoplasmosis" returned 31 free, full-text review articles on human participants. First 3 results:

Laboratory Diagnostics for Histoplasmosis.
 

Author(s): Marwan M Azar, Chadi A Hage

Journal: J. Clin. Microbiol.. 2017 06;55(6):1612-1620.

 

The diagnosis of histoplasmosis is based on a multifaceted approach that includes clinical, radiographic, and laboratory evidence of disease. The gold standards for laboratory diagnosis include demonstration of yeast on pathological examination of tissue and isolation of the mold ...

Last Updated: 31 Dec 1969

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Progressive disseminated histoplasmosis: a systematic review on the performance of non-culture-based diagnostic tests.
 

Author(s): Diego R Falci, Elias R Hoffmann, Diego D Paskulin, Alessandro C Pasqualotto

Journal: Braz J Infect Dis. ;21(1):7-11.

 

The diagnosis of progressive disseminated histoplasmosis is often a challenge to clinicians, especially due to the low sensitivity and long turnaround time of the classic diagnostic methods. In recent years, studies involving a variety of non-culture-based diagnostic tests have been ...

Last Updated: 31 Dec 1969

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[Histoplasmosis of the central nervous system in an immunocompetent patient].
 

Author(s): Natalia Osorio, Yúrika López, Juan Camilo Jaramillo

Journal: Biomedica. ;34(4):506-13.

 

Histoplasmosis is a multifaceted condition caused by the dimorphic fungi Histoplasma capsulatum whose infective spores are inhaled and reach the lungs, the primary organ of infection. The meningeal form, considered one of the most serious manifestations of this mycosis, is usually ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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