Dubin-Johnson Syndrome

Common Name(s)

Dubin-Johnson Syndrome, Hyperbilirubinemia type 2

Dubin-Johnson syndrome is a type of hereditary hyperbilirubinemia with a relatively benign course.  Symptoms may include a yellowish color to the skin (jaundice), and a liver that is sometimes enlarged and tender.   The symptoms often do not present until puberty or adulthood. The syndrome interferes with the body's ability to move bilirubin from the liver. In most cases, treatment is not required.  
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dubin-Johnson Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dubin-Johnson Syndrome" returned 28 free, full-text research articles on human participants. First 3 results:

Conjugated hyperbilirubinemia after surgery. A diagnosis of Dubin-Johnson syndrome confirmed by genetic testing.
 

Author(s): Maria Luisa Baranguán Castro, Ruth García Romero, María Dolores Miramar Gallart

Journal: Rev Esp Enferm Dig. 2017 Nov;109(11):801-802.

 

Dubin-Johnson syndrome is a rare benign inherited disorder, caused by mutations in ABCC2 gen, and it is characterized by predominantly conjugated hyperbilirubinemia that can be increased by intercurrent infectious illnesses or surgical procedures. We report the case of a 10 year-old ...

Last Updated: 31 Dec 1969

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Dubin-Johnson syndrome and intrahepatic cholestasis of pregnancy in a Sri Lankan family: a case report.
 

Author(s): Grace Angeline Malarnangai Kularatnam, Dilanthi Warawitage, Dinesha Maduri Vidanapathirana, Subashini Jayasena, Eresha Jasinge, Nalika de Silva, Kirinda Liyana Arachchige Manoj Sanjeeva Liyanarachchi, Pujitha Wickramasinghe, Manjit Singh Devgun, Veronique Barbu, Olivier Lascols

Journal:

 

Dubin-Johnson syndrome and intrahepatic cholestasis of pregnancy are rare chronic liver disorders. Dubin-Johnson syndrome may manifest as conjugated hyperbilirubinemia, darkly pigmented liver, presence of abnormal pigment in the parenchyma of hepatocytes and abnormal distribution ...

Last Updated: 31 Dec 1969

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IMAGES IN CLINICAL MEDICINE. Dubin-Johnson Syndrome.
 

Author(s): Kazuhiko Morii, Takeharu Yamamoto

Journal: N. Engl. J. Med.. 2016 Jul;375(1):e1.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dubin-Johnson Syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.