Hypopituitarism

Common Name(s)

Hypopituitarism

Hypopituitarism occurs when the body has low levels of certain hormones made by the pituitary gland.  The pituitary gland normally makes several hormones (including growth hormone, thyroid stimulating hormone, adrenocorticotropic hormone, prolactin, follicle stimulating hormone and luteinizing hormone, vasopressin, and oxytocin).  These hormones are important for directing body growth and development, and for regulating blood pressure and metabolism.  Symptoms of this condition vary and depend on which hormones are affected.  Treatment depends on the cause of this condition; once the cause is corrected, medication (hormone replacement therapy) must be taken to provide the body with the normal amount of hormones.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypopituitarism" for support, advocacy or research.

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Pituitary Network Association

To support, pursue, encourage, promote, and, where possible, fund research on pituitary disorders in a sustained and full-time effort to find a cure for these illnesses. The PNA will disseminate information helpful to the medical community, the public, and to pituitary patients and their families on matters regarding early detection, symptoms, treatments and resources available to patients with pituitary disease.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypopituitarism" for support, advocacy or research.

Logo
Pituitary Network Association

To support, pursue, encourage, promote, and, where possible, fund research on pituitary disorders in a sustained and full-time effort to find a cure for these illnesses. The PNA will disseminate information helpful to the medical community, the public, and to pituitary patients and their families on matters regarding early detection, symptoms, treatments and resources available to patients with pituitary disease.

http://www.pituitary.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypopituitarism" returned 215 free, full-text research articles on human participants. First 3 results:

Bilateral thalamic and mesencephalic infarctions with hypopituitarism as long-term complications postradiotherapy: A case report.
 

Author(s): Liang Hui, Hu Shijun, Liu Tao, Wen Guoqiang, Huang Shixiong

Journal: Medicine (Baltimore). 2018 Aug;97(34):e11917.

 

Radiation is widely used as the first-line treatment for nasopharyngeal carcinoma (NPC) and improves survival. Nevertheless, radiation also places the patients at risk of radiation-induced adverse effects, such as transient ischemic attack, ischemic stroke, hypopituitarism, and cranial ...

Last Updated: 31 Dec 1969

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Cerebrofacial arteriovenous metameric syndrome with hypopituitarism: a rare association.
 

Author(s): Justin Christopher Ng, Chinthaka Appuhamy, Wickly Lee

Journal:

 

Case of cerebrofacial arteriovenous metameric syndrome (CAMS) in a 9-year-old boy is described with arteriovenous malformation simultaneously involving the brain and face, with characteristic CAMS type 1 and 2 involvement. This patient demonstrates the wide spectrum of clinical manifestations ...

Last Updated: 31 Dec 1969

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[Long QT syndrome and polymorphic ventricular tachycardia due to hypopituitarism. Report of one case].
 

Author(s): José Miguel García-Castro, Antonia García-Martín, Emilio Guirao-Arrabal, Pedro Luis Carrillo-Alascio

Journal: Rev Med Chil. 2017 Jul;145(7):941-944.

 

Symptoms of hypopituitarism are usually chronic and nonspecific, but rarely the disease can have acute and life threatening manifestations. We report a 53 years old female with a pituitary adenoma that was admitted to our hospital because of syncope. The electrocardiogram showed sinus ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypopituitarism" returned 19 free, full-text review articles on human participants. First 3 results:

Four-year follow-up of a Wilson disease pedigree complicated with epilepsy and hypopituitarism: Case report with a literature review.
 

Author(s): Qi-Jie Zhang, Liu-Qing Xu, Chong Wang, Wei Hu, Ning Wang, Wan-Jin Chen

Journal: Medicine (Baltimore). 2016 Dec;95(49):e5331.

 

Wilson's disease (WD) is an autosomal recessive inherited disorder of copper metabolism with excellent prognosis if treated timely. However, WD is usually prone to neglect and misdiagnosis at an early stage. We reported a rare WD pedigree, and the clinical features, laboratory tests, ...

Last Updated: 31 Dec 1969

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How should we interrogate the hypothalamic-pituitary-adrenal axis in patients with suspected hypopituitarism?
 

Author(s): Aoife Garrahy, Amar Agha

Journal:

 

Hypopituitarism is deficiency of one or more pituitary hormones, of which adrenocorticotrophic hormone (ACTH) deficiency is the most serious and potentially life-threatening. It may occur in isolation or, more commonly as part of more widespread pituitary failure. Diagnosis requires ...

Last Updated: 31 Dec 1969

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Reversible Hypopituitarism Associated with Intravascular Large B-Cell Lymphoma: Case Report of Successful Immunochemotherapy.
 

Author(s): Yusuke Sawada, Sumiyasu Ishii, Yasuhiko Koga, Taku Tomizawa, Ayako Matsui, Takuya Tomaru, Atsushi Ozawa, Nobuyuki Shibusawa, Tetsurou Satoh, Hiroaki Shimizu, Junko Hirato, Masanobu Yamada

Journal: Tohoku J. Exp. Med.. 2016 03;238(3):197-203.

 

Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of diffuse large B-cell lymphoma. There have been only a limited number of reports regarding pituitary dysfunction associated with IVLBCL. We present a 71-year-old woman with hypopituitarism without any hypothalamic/pituitary ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pubertal Induction in Individuals With Hypogonadism
 

Status: Not yet recruiting

Condition Summary: Primary Amenorrhoea; Hypothalamic Amenorrhoea; Hypogonadotrophic Hypogonadism; Hypopituitarism; Turner's Syndrome; Primary Ovarian Insufficiency

 

Last Updated: 15 Aug 2016

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Lipolytic Effects of GH in Hypopituitary Patients in Vivo
 

Status: Recruiting

Condition Summary: Hypopituitarism; Insulin Resistance; Endocrine System Diseases; Glucose Metabolism Disorders; Metabolic Diseases; Pituitary Diseases; Brain Diseases

 

Last Updated: 20 May 2016

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Validation of a Questionnaire That Identifies the Reasons for Non-adherence to Existing Growth Hormone Therapy
 

Status: Not yet recruiting

Condition Summary: Growth Hormone Deficiency in Children

 

Last Updated: 13 Sep 2018

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