Hypospadias

Common Name(s)

Hypospadias

Hypospadias is a birth defect in which the urethra (the tube that drains urine from the bladder) is abnormally located on the underside of the penis instead of at the tip. It is typically diagnosed at birth, but less severe hypospadius can potentially go overlooked. Hypospadias is caused by an inbalance of hormones required for normal development of the urethra. Treatment involves surgery to reposition the urethra, most commonly resulting in normal appearance and function of the penis.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypospadias" for support, advocacy or research.

AIS-DSD Support Group

The AIS-DSD Support Group is a compassionate community of individuals, families and allies collaborating to promote better lives and informed decision-making through advancement of knowledge so no one will face a diagnosis alone.

Last Updated: 12 Jan 2015

View Details
Logo
Hypospadias Epispadias Association

The Hypospadias and Epispadias Association, Inc. (HEA) is an organization founded in the year 2000 for the support and education of people born with hypospadias or epispadias and their families, loved ones, and medical care givers.

Last Updated: 25 Mar 2013

View Details
Pull-thru Network, Inc.

The Pull-thru Network is a volunteer-based organization dedicated to providing education, information, support and advocacy for those individuals, and the families of those individuals, who are affected by any congenital anorectal, colorectal or urogenital disorder and any of the variety of related diagnoses.

Last Updated: 8 Nov 2012

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypospadias" for support, advocacy or research.

AIS-DSD Support Group

The AIS-DSD Support Group is a compassionate community of individuals, families and allies collaborating to promote better lives and informed decision-making through advancement of knowledge so no one will face a diagnosis alone.

http://www.aisdsd.org

Last Updated: 12 Jan 2015

View Details
Logo
Hypospadias Epispadias Association

The Hypospadias and Epispadias Association, Inc. (HEA) is an organization founded in the year 2000 for the support and education of people born with hypospadias or epispadias and their families, loved ones, and medical care givers.

http://www.HEAinfo.org

Last Updated: 25 Mar 2013

View Details
Pull-thru Network, Inc.

The Pull-thru Network is a volunteer-based organization dedicated to providing education, information, support and advocacy for those individuals, and the families of those individuals, who are affected by any congenital anorectal, colorectal or urogenital disorder and any of the variety of related diagnoses.

http://www.PullthruNetwork.org

Last Updated: 8 Nov 2012

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypospadias" returned 312 free, full-text research articles on human participants. First 3 results:

The hypospadias classification affected the surgical outcomes of staged oral mucosa graft urethroplasty in hypospadias reoperation: An observational study.
 

Author(s): Dachao Zheng, Shi Fu, Wenji Li, Minkai Xie, Jianhua Guo, Haijun Yao, Zhong Wang

Journal: Medicine (Baltimore). 2017 Nov;96(47):e8238.

 

The staged graft urethroplasty is a recommended technique for repairing complex hypospadias. This retrospective study aimed to investigate the outcomes of this technique in hypospadias patients undergoing reoperation and to analyze the underlying contributing factors including age, ...

Last Updated: 31 Dec 1969

Go To URL
Surgery for distal hypospadias: what about the catheter?
 

Author(s): Maria-Grazia Scarpa, Giordano Perin, Massimo Di Grazia, Daniela Codrich, Federica Pederiva, Edoardo Guida, Maria Antonietta Lembo, Antonio Giannotta, J├╝rgen Schleef

Journal:

 

No agreed recommendations exist for timing of urethral stent removal, after distal hypospadias surgery. We compared our preliminary case series with outcomes from literature: 18/44 patients were treated with catheter and 26/44 without it. The surgical outcome was comparable in the ...

Last Updated: 31 Dec 1969

Go To URL
Comment on: Maternal Exposure to Domestic Hair Cosmetics and Occupational Endocrine Disruptors Is Associated with a Higher Risk of Hypospadias in the Offspring. Int. J. Environ. Res. Public Health 2017, 14, 27.
 

Author(s): Mark Elwood, Dillon O'Brien, Katie-Anne Budgen

Journal:

 

There are considerable inconsistencies in the results of Haraux et al. [1].[...].

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypospadias" returned 26 free, full-text review articles on human participants. First 3 results:

Hypospadias, all there is to know.
 

Author(s): H J R van der Horst, L L de Wall

Journal: Eur. J. Pediatr.. 2017 Apr;176(4):435-441.

 

Hypospadias is one of the most common congenital anomalies in men. The condition is typically characterized by proximal displacement of the urethral opening, penile curvature, and a ventrally deficient hooded foreskin. In about 70%, the urethral meatus is located distally on the penile ...

Last Updated: 31 Dec 1969

Go To URL
Impact of preoperative hormonal stimulation on postoperative complication rates after hypospadias repair: a meta-analysis.
 

Author(s): Min Chao, Yin Zhang, Chaozhao Liang

Journal: Minerva Urol Nefrol. 2017 Jun;69(3):253-261.

 

To improve the surgical outcome of hypospadias repair surgery, preoperative hormonal stimulation (PHS) has been proposed. We conducted a meta-analysis to evaluate the impact of preoperative hormonal stimulation (PHS) treatment on complication rates following hypospadias repair surgery.

Last Updated: 31 Dec 1969

Go To URL
Diethylstilbestrol-induced mouse hypospadias: "window of susceptibility".
 

Author(s): Adriane Watkins Sinclair, Mei Cao, Laurence Baskin, Gerald R Cunha

Journal: Differentiation. ;91(1-3):1-18.

 

This review presents published and novel results that define the programming window for diethylstilbestrol (DES)-induced abnormal development of the mouse penis. These data indicate that DES has its greatest effect during the period of most intense penile morphogenesis, namely postnatal ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 8 Nov 2017

Go to URL
Effect of Caudal and Penile Block on Hypospadias Repair Complications
 

Status: Recruiting

Condition Summary: Hypospadias

 

Last Updated: 6 Sep 2017

Go to URL
Caudal vs Local Anesthesia in Hypospadias
 

Status: Recruiting

Condition Summary: Hypospadias

 

Last Updated: 12 Mar 2018

Go to URL