Interstitial cystitis

Common Name(s)

Interstitial cystitis

Interstitial cystitis (IC) is a condition that causes discomfort or pain in the bladder and abdomen. Symptoms may vary, but often include an urgent or frequent need to urinate. Many of the individuals affected by IC are women. Because IC varies so much in symptoms and severity, most researchers believe it is not one, but several diseases. In recent years, scientists have started to use the terms bladder pain syndrome (BPS) or painful bladder syndrome (PBS) to describe cases with painful urinary symptoms that may not meet the strictest definition of IC. While there is no cure for IC/PBS, in many cases, the symptoms can be managed. Treatments include dietary and lifestyle changes; distending, or inflating, the bladder; bathing the inside of the bladder with a medicine solution; oral medicines and in rare cases, surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial cystitis" for support, advocacy or research.

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Interstitial Cystitis Association

The Interstitial Cystitis Association (ICA) advocates for research dedicated to discovery of a cure and better treatments, raises awareness, and serves as a central hub for the healthcare providers, researchers and millions of patients who suffer with constant urinary urgency and frequency and extreme bladder pain called IC, or interstitial cystitis. Vision Conquering IC. Changing lives. Mission Early diagnosis and optimal care with dignity for people affected by IC

Last Updated: 19 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial cystitis" for support, advocacy or research.

Logo
Interstitial Cystitis Association

The Interstitial Cystitis Association (ICA) advocates for research dedicated to discovery of a cure and better treatments, raises awareness, and serves as a central hub for the healthcare providers, researchers and millions of patients who suffer with constant urinary urgency and frequency and extreme bladder pain called IC, or interstitial cystitis. Vision Conquering IC. Changing lives. Mission Early diagnosis and optimal care with dignity for people affected by IC

http://www.ichelp.org

Last Updated: 19 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial cystitis" returned 276 free, full-text research articles on human participants. First 3 results:

Urinary and psychological outcomes in women with interstitial cystitis/bladder pain syndrome following hyaluronic acid treatment.
 

Author(s): Ching-Chung Liang, Yi-Hao Lin, Wu-Chiao Hsieh, Lulu Huang

Journal: Taiwan J Obstet Gynecol. 2018 Jun;57(3):360-363.

 

To investigate urinary and psychological symptoms in patients with interstitial cystitis/bladder pain syndrome (IC/BPS) after intravesical hyaluronic acid (HA) treatment.

Last Updated: 31 Dec 1969

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Urodynamic characteristics might be variable in bladder pain syndrome/interstitial cystitis patients with different non-bladder co-morbid conditions.
 

Author(s): Wei-Ming Cheng, Yu-Hua Fan, Alex T L Lin

Journal: J Chin Med Assoc. 2018 03;81(3):248-254.

 

The aim of the study was to identify the impact of non-bladder co-morbid conditions on the urodynamic characteristics of patients with bladder pain syndrome/interstitial cystitis.

Last Updated: 31 Dec 1969

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Development of an interstitial cystitis risk score for bladder permeability.
 

Author(s): Laura E Lamb, Joseph J Janicki, Sarah N Bartolone, Kenneth M Peters, Michael B Chancellor

Journal:

 

Interstitial cystitis/bladder pain syndrome (IC) is a multifactorial syndrome of severe pelvic and genitalia pain and compromised urinary function; a subset of IC patients present with Hunner's lesions or ulcers on their bladder walls (UIC). UIC is diagnosed by cystoscopy, which may ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial cystitis" returned 33 free, full-text review articles on human participants. First 3 results:

Crosstalk between the immune system and neural pathways in interstitial cystitis/bladder pain syndrome.
 

Author(s): Kevin Duh, Michael G Funaro, William DeGouveia, Sonia Bahlani, Dominic Pappas, Souhel Najjar, Inna Tabansky, Robert Moldwin, Joel N H Stern

Journal: Discov Med. 2018 05;25(139):243-250.

 

Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a condition causing intense pelvic pain and urinary symptoms. While it is thought to affect millions of people and significantly impair quality of life, difficulty with diagnosis and a lack of reliably effective treatment options ...

Last Updated: 31 Dec 1969

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Systematic Review and Meta-Analysis of Intravesical Hyaluronic Acid and Hyaluronic Acid/Chondroitin Sulfate Instillation for Interstitial Cystitis/Painful Bladder Syndrome.
 

Author(s): Jung-Soo Pyo, Won Jin Cho

Journal: Cell. Physiol. Biochem.. 2016 ;39(4):1618-25.

 

To assess the efficacy of intravesical hyaluronic acid (HA) and HA/chondroitin sulfate (CS) instillation in patients with interstitial cystitis/painful bladder syndrome by systematic review and meta-analysis.

Last Updated: 31 Dec 1969

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Intravesical Botulinum Toxin A Injections for Bladder Pain Syndrome/Interstitial Cystitis: A Systematic Review and Meta-Analysis of Controlled Studies.
 

Author(s): Junpeng Wang, Qiang Wang, Qinghui Wu, Yang Chen, Peng Wu

Journal:

 

BACKGROUND The role of intravesical botulinum toxin A (BTX-A) injections in bladder pain syndrome/interstitial cystitis (BPS/IC) has not been clearly defined. The aim of this study was to evaluate high-level evidence regarding the efficacy and safety of BTX-A injections for BPS/IC. ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Efficacy of Urine Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome (Pilot Study)
 

Status: Recruiting

Condition Summary: Chronic Interstitial Cystitis

 

Last Updated: 6 Jul 2017

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Genetic and Histopathologic Characteristics of Interstitial Cystitis
 

Status: Recruiting

Condition Summary: Interstitial Cystitis

 

Last Updated: 1 May 2018

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The Effects of Mindfulness-based Stress Reduction in Interstitial Cystitis Patients
 

Status: Not yet recruiting

Condition Summary: Interstitial Cystitis

 

Last Updated: 25 Oct 2018

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