Juvenile idiopathic arthritis

Common Name(s)

Juvenile idiopathic arthritis, JRA, Pediatric arthritis, JIA, Juvenile rheumatoid arthritis

Juvenile idiopathic arthritis (JIA), also known as juvenile rheumatoid arthritis (JRA), is the most common form of arthritis in children ages 6 months to 17 years. JIA causes inflammation (redness, swelling, heat, pain) in one, or many, joints (areas of the body where two bones fit together). JIA is not the same as the adult type of arthritis. There are seven different types of JIA (see related conditions below).

JIA causes pain, stiffness, swelling, and redness most commonly in the knees and joints of hands and feet. The joint may not move fully (decreased range of motion). Symptoms are usually worse in the morning or after a nap. The symptoms may go away after a few months or be lifelong. Some types of JIA can affect other parts of the body, causing swollen lymph nodes, rashes and fever, eye inflammation and growth problems.

The cause of JIA is unknown (idiopathic). However, it is believed that both environmental and genetic factors play a role. JIA may be an autoimmune or autoinflammatory disease. Usually, our immune system protects us from illness and infection by attacking viruses, bacteria and other foreign bodies. Sometimes our immune system attacks its own healthy cells. Different parts of our immune system can go wrong causing either an autoimmune or an autoinflammatory response.

Girls are more likely to have JIA. Certain viruses may also increase a child’s risk. To diagnose this condition, your child’s doctor or specialist may perform a physical exam, blood tests and special imaging tests of your child’s joints (using X-ray, MRI and video imaging). Although there is no cure for JIA, there are treatments that help reduce pain and swelling. These treatments include medications, therapy, and possibly surgery. If your child has been diagnosed with JIA, talk with their doctor about the most current treatment options. Support groups are also a good source of information and will help connect you with other families.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Juvenile idiopathic arthritis" for support, advocacy or research.

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International Foundation for Autoimmune Arthritis

We are committed to eliminating the adversity caused by autoimmune arthritis by uniting resources that will raise global awareness, providing wellness education and support, and conducting patient-centered research that will improve the quality of life for those affected by these diseases.

Last Updated: 18 Sep 2014

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International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

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Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

Last Updated: 2 Aug 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Juvenile idiopathic arthritis" for support, advocacy or research.

Logo
International Foundation for Autoimmune Arthritis

We are committed to eliminating the adversity caused by autoimmune arthritis by uniting resources that will raise global awareness, providing wellness education and support, and conducting patient-centered research that will improve the quality of life for those affected by these diseases.

http://www.ifautoimmunearthritis.org

Last Updated: 18 Sep 2014

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International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

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Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

http://www.isabellasaviary.com

Last Updated: 2 Aug 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Juvenile idiopathic arthritis" returned 783 free, full-text research articles on human participants. First 3 results:

"I just want to get better": experiences of children and youth with juvenile idiopathic arthritis in a home-based exercise intervention.
 

Author(s): Joanie Sims-Gould, Douglas L Race, Heather Macdonald, Kristin M Houghton, Ciarán M Duffy, Lori B Tucker, Heather A McKay

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Physical activity is essential for ensuring optimal physical function and fitness in children with juvenile idiopathic arthritis (JIA). Although exercise intervention trials informed current clinical practice, few studies addressed why children with JIA do or do not participate in ...

Last Updated: 31 Dec 1969

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Reliability of ultrasonography to detect inflammatory lesions and structural damage in juvenile idiopathic arthritis.
 

Author(s): Lucio Ventura-Ríos, Enrique Faugier, Laura Barzola, L B De la Cruz-Becerra, Guadalupe Sánchez-Bringas, Andrés Rodríguez García, Rocío Maldonado, Johannes Roth, Cristina Hernández-Díaz

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Musculoskeletal Ultrasonography (MSUS) is an important tool for the clinical assessment in Juvenile Idiopathic Arthritis (JIA). The objective of this study was to evaluate the reliability of MSUS to detect elementary lesions: synovitis, tenosynovitis, cartilage damage and bone erosions ...

Last Updated: 31 Dec 1969

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Temporomandibular joint disorders as the only manifestation of juvenile idiopathic arthritis: a case report.
 

Author(s): José Renato Ribeiro Pinto, Irineu Gregnanin Pedron, Estevam Rubens Utumi, Milton Edson Miranda, Elisa Cruz Pereira Pinto, Leopoldo Penteado Nucci

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Juvenile idiopathic arthritis is a term used to include all chronic childhood arthritis of unknown etiology. It is characterized by chronic inflammation persisting for at least 6 weeks, beginning before 16 years of age. The characteristics present are chronic synovitis, arthralgia, ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Juvenile idiopathic arthritis" returned 114 free, full-text review articles on human participants. First 3 results:

Dutch juvenile idiopathic arthritis patients, carers and clinicians create a research agenda together following the James Lind Alliance method: a study protocol.
 

Author(s): Casper G Schoemaker, Wineke Armbrust, Joost F Swart, Sebastiaan J Vastert, Jorg van Loosdregt, Anouk Verwoerd, Caroline Whiting, Katherine Cowan, Wendy Olsder, Els Versluis, Rens van Vliet, Marlous J Fernhout, Sanne L Bookelman, Jeannette Cappon, J Merlijn van den Berg, Ellen Schatorjé, Petra C E Hissink Muller, Sylvia Kamphuis, Joke de Boer, Otto T H M Lelieveld, Janjaap van der Net, Karin R Jongsma, Annemiek van Rensen, Christine Dedding, Nico M Wulffraat

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Research on Juvenile Idiopathic Arthritis (JIA) should support patients, caregivers/parents (carers) and clinicians to make important decisions in the consulting room and eventually to improve the lives of patients with JIA. Thus far these end-users of JIA-research have rarely been ...

Last Updated: 31 Dec 1969

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Methotrexate in juvenile idiopathic arthritis: advice and recommendations from the MARAJIA expert consensus meeting.
 

Author(s): Giovanna Ferrara, Greta Mastrangelo, Patrizia Barone, Francesco La Torre, Silvana Martino, Giovanni Pappagallo, Angelo Ravelli, Andrea Taddio, Francesco Zulian, Rolando Cimaz,

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Conventional pharmacological therapies for the treatment of juvenile idiopathic arthritis (JIA) consist of non-biological, disease-modifying antirheumatic drugs, among which methotrexate (MTX) is the most commonly prescribed. However, there is a lack of consensus-based clinical and ...

Last Updated: 31 Dec 1969

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Vitamin D and juvenile idiopathic arthritis.
 

Author(s): Sarah L Finch, Alan M Rosenberg, Hassan Vatanparast

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Vitamin D has been implicated in the pathogenesis of autoimmune diseases. While the roles of vitamin D in other autoimmune diseases have been investigated, less is known about the role of vitamin D in chronic childhood arthritis.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pharmacovigilance in Juvenile Idiopathic Arthritis Patients Treated With Biologic Agents and/or Methotrexate
 

Status: Recruiting

Condition Summary: Juvenile Idiopathic Arthritis

 

Last Updated: 2 Mar 2018

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Massage Therapy in Juvenile Idiopathic Arthritis
 

Status: Recruiting

Condition Summary: Juvenile Idiopathic Arthritis

 

Last Updated: 28 Mar 2018

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