Juvenile myoclonic epilepsy

Common Name(s)

Juvenile myoclonic epilepsy

Juvenile myoclonic epilepsy is an epilepsy syndrome characterized by myoclonic jerks (quick jerks of the arms or legs), generalized tonic-clonic seizures (GTCSs), and sometimes, absence seizures.  The seizures of juvenile myoclonic epilepsy often occur when people first awaken in the morning, especially if they are sleep-deprived. Drinking alcohol and psychological stress may also make these seizures more likely.  Onset typically occurs around adolesence in otherwise healthy children.  The exact cause of juvenile myoclonic epilepsy remains unknown.  Although patients usually require lifelong treatment with anticonvulsants, their overall prognosis is generally good.


 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Juvenile myoclonic epilepsy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Juvenile myoclonic epilepsy" returned 165 free, full-text research articles on human participants. First 3 results:

Subcortical grey matter changes in juvenile myoclonic epilepsy.
 

Author(s): Ji Hyun Kim, Jung Bin Kim, Sang-Il Suh, Dong Wook Kim

Journal:

 

Recent neuroimaging studies have provided converging evidence of structural and functional abnormalities of the thalamus in patients with juvenile myoclonic epilepsy (JME). There has also been limited evidence indicating involvement of the subcortical grey matter structures other ...

Last Updated: 31 Dec 1969

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Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1.
 

Author(s): Franziska Wielaender, Riika Sarviaho, Fiona James, Marjo K Hytönen, Miguel A Cortez, Gerhard Kluger, Lotta L E Koskinen, Meharji Arumilli, Marion Kornberg, Andrea Bathen-Noethen, Andrea Tipold, Kai Rentmeister, Sofie F M Bhatti, Velia Hülsmeyer, Irene C Boettcher, Carina Tästensen, Thomas Flegel, Elisabeth Dietschi, Tosso Leeb, Kaspar Matiasek, Andrea Fischer, Hannes Lohi

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2017 03;114(10):2669-2674.

 

The clinical and electroencephalographic features of a canine generalized myoclonic epilepsy with photosensitivity and onset in young Rhodesian Ridgeback dogs (6 wk to 18 mo) are described. A fully penetrant recessive 4-bp deletion was identified in the DIRAS family GTPase 1 () gene ...

Last Updated: 31 Dec 1969

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Exploring psychiatric comorbidities and their effects on quality of life in patients with temporal lobe epilepsy and juvenile myoclonic epilepsy.
 

Author(s): Devrimsel H Ertem, Ayten C Dirican, Agah Aydın, Sevim Baybas, Vedat Sözmen, Musa Ozturk, Yavuz Altunkaynak

Journal: Psychiatry Clin. Neurosci.. 2017 Apr;71(4):280-288.

 

The relation of epilepsy with psychiatric disorders is of great interest to researchers due to its behavioral, social, and cognitive outcomes. In this study, we explored psychiatric comorbidity and its effects on quality of life (QOL) in patients with mesial temporal lobe epilepsy ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Juvenile myoclonic epilepsy" returned 12 free, full-text review articles on human participants. First 3 results:

Genetic susceptibility in Juvenile Myoclonic Epilepsy: Systematic review of genetic association studies.
 

Author(s): Bruna Priscila Dos Santos, Chiara Rachel Maciel Marinho, Thalita Ewellyn Batista Sales Marques, Layanne Kelly Gomes Angelo, Maísa Vieira da Silva Malta, Marcelo Duzzioni, Olagide Wagner de Castro, João Pereira Leite, Fabiano Timbó Barbosa, Daniel Leite Góes Gitaí

Journal:

 

Several genetic association investigations have been performed over the last three decades to identify variants underlying Juvenile Myoclonic Epilepsy (JME). Here, we evaluate the accumulating findings and provide an updated perspective of these studies.

Last Updated: 31 Dec 1969

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Juvenile myoclonic epilepsy as a spectrum disorder: A focused review.
 

Author(s): Betül Baykan, Peter Wolf

Journal: Seizure. 2017 Jul;49():36-41.

 

In consequence of newer research juvenile myoclonic epilepsy (JME) is no longer seen as a homogeneous disease. The causes of the existing variance are only partially known yet. We discuss to what extent the phenotypical spectrum of this polygenetically determined disorder expresses ...

Last Updated: 31 Dec 1969

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Juvenile myoclonic epilepsy: Challenges on its 60th anniversary.
 

Author(s): Elza Márcia Yacubian

Journal: Seizure. 2017 Jan;44():48-52.

 

Since its initial 1957 description, juvenile myoclonic epilepsy (JME) has been recognized as a common epileptic syndrome worldwide.

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Biology of Juvenile Myoclonic Epilepsy
 

Status: Recruiting

Condition Summary: Juvenile Myoclonic Epilepsy

 

Last Updated: 12 Jan 2018

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