Limbic encephalitis

Common Name(s)

Limbic encephalitis

Limbic encephalitis is a condition marked by the inflammation of the limbic system and other parts of the brain. The cardinal sign of limbic encephalitis is a severe impairment of short-term memory; however, symptoms may also include confusion, psychiatric symptoms, and seizures. The symptoms typically develop over a few weeks or months, but they may evolve over a few days. Delayed diagnosis is common, but improvements are being made to assist in early detection. Early diagnosis may improve the outcome of limbic encephalitis.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Limbic encephalitis" for support, advocacy or research.

Logo
Autoimmune Encephalitis Alliance

The Autoimmune Encephalitis Alliance improves the lives of patients with autoimmune encephalitis by promoting collaboration across clinical and basic research and by creating a community of patients, families and caregivers so that no one faces autoimmune encephalitis alone.

Last Updated: 25 Mar 2013

View Details
Encephalitis Global Inc.

Encephalitis Global (E Global) is a U.S.A. 501(c)(3) public charity formed in 2005 as an alliance connecting encephalitis survivors and caregivers around the world. E Global strives to raise awareness, aiming to promote swift diagnosis, to alleviate unnecessary suffering and to prevent untimely death.

Last Updated: 19 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Limbic encephalitis" for support, advocacy or research.

Logo
Autoimmune Encephalitis Alliance

The Autoimmune Encephalitis Alliance improves the lives of patients with autoimmune encephalitis by promoting collaboration across clinical and basic research and by creating a community of patients, families and caregivers so that no one faces autoimmune encephalitis alone.

http://www.aealliance.org

Last Updated: 25 Mar 2013

View Details
Encephalitis Global Inc.

Encephalitis Global (E Global) is a U.S.A. 501(c)(3) public charity formed in 2005 as an alliance connecting encephalitis survivors and caregivers around the world. E Global strives to raise awareness, aiming to promote swift diagnosis, to alleviate unnecessary suffering and to prevent untimely death.

http://www.encephalitisglobal.org

Last Updated: 19 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Limbic encephalitis" returned 147 free, full-text research articles on human participants. First 3 results:

A case report of limbic encephalitis in a metastatic colon cancer patient during first-line bevacizumab-combined chemotherapy.
 

Author(s): Laura Attademo, Stefano De Falco, Mario Rosanova, Marcello Esposito, Federica Mazio, Francesca Foschini, Antonio Santaniello, Giovanni Fiore, Elide Matano, Fiore Manganelli, Chiara Carlomagno

Journal: Medicine (Baltimore). 2018 Mar;97(9):e0011.

 

Paraneoplastic limbic encephalitis (PLE) is one of the most common causes of neurologic paraneoplastic syndromes, with unclear pathogenesis. While several reports published in the last decades showed the occurrence of PLE in a variety of cancers, only a few cases have been associated ...

Last Updated: 31 Dec 1969

Go To URL
Gamma-aminobutyric acid-B limbic encephalitis and asystolic cardiac arrest: a case report.
 

Author(s): Christopher A Ovens, Angelo Jayamanne, Andrew Duggins

Journal:

 

Gamma-aminobutyric acid-B receptor autoantibodies are becoming an increasingly recognized contributor to the spectrum of autoimmune limbic encephalitis. They are classically associated with seizures and behavioral disturbance, and may coexist with other autoantibodies. Many are paraneoplastic, ...

Last Updated: 31 Dec 1969

Go To URL
Anti-Ma2-associated limbic encephalitis with coexisting chronic inflammatory demyelinating polyneuropathy in a patient with non-Hodgkin lymphoma: A case report.
 

Author(s): Weina Ju, Baochang Qi, Xu Wang, Yu Yang

Journal: Medicine (Baltimore). 2017 Oct;96(40):e8228.

 

We report the rare case of a 74-year-old man with anti-Ma2-associated paraneoplastic neurologic syndrome (PNS), and review and analyze the clinical manifestations, diagnosis, and treatment of the disease.

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Limbic encephalitis" returned 13 free, full-text review articles on human participants. First 3 results:

Paraneoplastic limbic encephalitis associated with mixed olfactory neuroblastoma and craniopharyngioma: A case report and literature review.
 

Author(s): Hiroshi Nagafuji, Hidenori Yokoi, Masachika Fujiwara, Dai Sato, Koichiro Saito

Journal: Medicine (Baltimore). 2018 Jun;97(24):e10932.

 

Paraneoplastic limbic encephalitis (PLE) is a rare disorder of the nervous system associated with malignant disease. It has a subacute onset with the following symptoms: cognitive dysfunction, seizures, irritability, hallucinations, and short-term memory loss. Herein, we report the ...

Last Updated: 31 Dec 1969

Go To URL
Paraneoplastic Limbic Encephalitis in a Human Epidermal Growth Factor Receptor-2-positive Gastric Cancer Patient Treated with Trastuzumab-combined Chemotherapy: A Case Report and Literature Review.
 

Author(s): Yu Uneno, Akira Yokoyama, Yoshitaka Nishikawa, Taro Funakoshi, Yoshinao Ozaki, Ikuo Aoyama, Kiichiro Baba, Daisuke Yamaguchi, Shuko Morita, Yukiko Mori, Masashi Kanai, Hisanori Kinoshita, Takeshi Inoue, Nobukatsu Sawamoto, Riki Matsumoto, Shigemi Matsumoto, Manabu Muto

Journal: Intern. Med.. ;55(18):2605-9.

 

Paraneoplastic neurological syndromes (PNSs) are rare nervous system dysfunctions in cancer patients, which are primarily observed with small-cell lung cancer, gynecological cancer, and thymoma. We herein present an uncommon case of PNS in an anti-Hu antibody-positive patient with ...

Last Updated: 31 Dec 1969

Go To URL
Autoantibody-mediated encephalitis: Not just paraneoplastic, not just limbic, and not untreatable.
 

Author(s): Adham Jammoul, Yuebing Li, Alexander Rae-Grant

Journal: Cleve Clin J Med. 2016 Jan;83(1):43-53.

 

Autoantibody-mediated encephalitis is a heterogeneous group of recently identified disorders, all caused by autoimmunity directed against components of the central nervous system. Despite severe and even prolonged neurologic deficits, dramatic improvements may occur with aggressive treatment.

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Antibodies Causing Epilepsy Syndromes: The ACES Study.
 

Status: Recruiting

Condition Summary: Auto-immune Encephalitis; Epilepsy

 

Last Updated: 5 Sep 2018

Go to URL