Malignant fibrous histiocytoma is a rare form of cancer characterized by abnormal cell growth in the fibrous support tissue or the bone. Individuals with this disorder may grow harmful tumors in the muscles and bone that can spread to the rest of the body if not diagnosed and treated early. The abnormal cell growth usually develops in the extremities (toes, fingers etc.), but can also form anywhere in the body. This form of cancer can thus cause individuals to be less capable of performing important movements, like walking and running. Some individuals may loss their ability to move certain parts of their body (paralysis). Common symptoms include weight loss, abdominal pain and breathing problems. Diagnosis may require blood tests and imaging studies such as a CT scan. A physician may also need to take a biopsy, which is where they surgically remove a small portion of the tumor to look at under a microscope. Treatment is developed on a case-by-case basis and may include a combination of chemotherapy, radiation, and surgery.