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Mast cell disease
Mastocytosis
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Overview
Mastocytosis is a disorder that can occur in both children and adults. It is caused by the presence of too many mast cells in the body. Mast cells contain substances such as histamine that regulate allergic reactions. Signs and symptoms of mastocytosis may include musculoskeletal pain, abdominal discomfort, nausea, vomiting, ulcers, diarrhea, and skin lesions. Treatment may include medications such as antihistamines (to prevent the effect of mast cell histamine) and anticholinergics (to relieve intestinal cramping).
There are two broad categories of mastocytosis, cutaneous and systemic. Cutaneous mastocytosis only affects the skin and is usually diagnosed in children. Systemic mastocytosis affects more than one part of the body and is usually diagnosed in adults. GARD provides additional information on cutaneous mastocytosis and systemic mastocytosis. Source: Genetic and Rare Diseases Information Center (GARD), supported by ORDR-NCATS and NHGRI.
There are two broad categories of mastocytosis, cutaneous and systemic. Cutaneous mastocytosis only affects the skin and is usually diagnosed in children. Systemic mastocytosis affects more than one part of the body and is usually diagnosed in adults. GARD provides additional information on cutaneous mastocytosis and systemic mastocytosis. Source: Genetic and Rare Diseases Information Center (GARD), supported by ORDR-NCATS and NHGRI.
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Genetic & Rare Diseases Information Center (GARD)
GARD provides the public with access to current, reliable, and easy-to-understand information about rare or genetic diseases in English or Spanish.
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Free membership, local support groups and online support
https://tmsforacure.org/membership/
https://tmsforacure.org/resources/support-groups-2/
https://tmsforacure.org/resources/online-support-communities/