Mental retardation - myopathy - short stature - endocrine defect refers to a form of intellectual disability that is characterized mainly by below-average mental ability, problems with muscle function, an abnormally short body frame, and hormone problems. Thus, individuals with this form of intellectual disability often have problems with tasks involving physical activity. Hormones are chemicals used by the body to send different signals to various organs or the brain. Imbalances in these hormones, such as those created by this condition, can cause patients to have abnormal patterns of development. Like other individuals with intellectual disability, an individual with this condition often has problems with reasoning and solving problems, as well as performing day-to-day tasks. The condition is often diagnosed during childhood. Doctors diagnose this form of intellectual disability if muscle problems and a short body frame are observed. Signs like walking and talking late, slow mastering of basic tasks, and having difficulty remembering things may also suggest this condition in children. Treatment depends on the specific needs of the patient. Physical therapists often help patients develop an exercise program to increase muscle strength. Endocrinologists may suggest patients to undergo hormone replacement or to take hormone supplements to treat the hormone imbalance symptoms. Doctors seek help from various therapists and community services to provide support and care for families affected by intellectual disability.